CD44 as a Conserved Biomarker and Functional Modulator of Neuroinflammation in Multiple Sclerosis and Beyond
CD44 Role in Neuroinflammation CD44 is a multifaceted cell surface glycoprotein that plays a crucial role in a variety of […]
A Mouse Model of Single and Repetitive Rotational Closed Head Concussive Brain Injury
Study Overview This study investigates the effects of both single and repetitive rotational closed head concussive injuries using a mouse
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Circulating microRNAs: A Potential Biomarker in TBI and PTSD War Veterans
Biological Basis of Circulating Micrornas Circulating microRNAs (miRNAs) are small, non-coding RNA molecules that play a crucial role in regulating
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Proteomic comparison of hippocampal neurofibrillary tangles in PART, intermediate Alzheimer’s disease and advanced Alzheimer’s disease
Study Overview This study focuses on a detailed comparative analysis of proteomic differences present in hippocampal neurofibrillary tangles associated with
Predictors of Multiple Sclerosis After Clinically Isolated Syndrome: A Systematic Review and Meta-Analysis
Research Context Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system, characterized by demyelination and neurodegeneration.
Traumatic brain injury and neurological stealth syndromes
Understanding Traumatic Brain Injury Traumatic brain injury (TBI) represents a significant health concern, resulting from an external force that impacts
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Pediatric traumatic brain injury elicits acute neuroinflammation and long-term changes in social, cognitive, and decision-making behaviors in male and female rats
Pediatric traumatic brain injury models Animal models are a critical aspect of understanding pediatric traumatic brain injury (TBI). These models
Therapeutic Effects of Combined 6-Shogaol and Ibudilast on Neuroinflammation and Behavioral Deficits in a Cuprizone Mouse Model of Multiple Sclerosis
Study Overview The research aimed to explore the combined effects of 6-Shogaol, a natural compound found in ginger, and Ibudilast,
Phenotype-guided Management of Post-traumatic Headache: An Update on Pathophysiology and Treatment
Pathophysiological Insights The mechanisms underlying post-traumatic headache (PTH) are complex and multifaceted, reflecting the intricacies of brain physiology and the
Therapeutic Effect of Alpha-Pinene on In Vitro and In Vivo Models of Mild Traumatic Brain Injury
Therapeutic Potential of Alpha-Pinene Alpha-pinene, a natural compound abundant in pine trees and various other plants, has garnered significant attention