Role of sirtuin 2 in the brain is cell-type and context-dependent: Implications for therapeutic targeting
Role of Sirtuin 2 in Neuronal Function Sirtuin 2 (SIRT2) is a member of the sirtuin family of proteins, which […]
ALDH2 deficiency exacerbates acrolein-mediated neuropathology in multiple sclerosis
Study Overview This research explores the role of ALDH2 deficiency in the context of multiple sclerosis (MS) and its interaction
ALDH2 deficiency exacerbates acrolein-mediated neuropathology in multiple sclerosis Read Post »
Apolipoprotein E Deficiency Attenuates Neuroinflammatory Responses and Demyelination in Experimental Autoimmune Encephalomyelitis
Study Overview Recent research has illuminated the pivotal role of Apolipoprotein E (ApoE) in modulating immune responses within the central
Signaling pathways driving multiple sclerosis: From mechanisms to natural‑product interventions
Signaling Pathways in Multiple Sclerosis Multiple sclerosis (MS) is a complex autoimmune disease characterized by the immune system’s attack on
Radiofrequency and pulsed magnetic fields attenuate LPS-induced neuroinflammation and demyelination via PI3K/AKT/HIF-1alpha-mediated neurovascular protection
Therapeutic Mechanisms of Radiofrequency and Pulsed Fields The therapeutic mechanisms underlying the effects of radiofrequency (RF) and pulsed magnetic fields
Retinal macrophage-like cell activation and ganglion cell layer thinning are associated with disability and MRI lesion burden in multiple sclerosis
Retinal Macrophage Activation and Its Role Retinal macrophages, a specialized form of immune cells found in the eye, play a
Retinal macrophage-like cell activation and ganglion cell layer thinning are associated with disability and MRI lesion burden in multiple sclerosis
Study Overview The research examined the link between retinal macrophage-like cell activation and the thinning of the ganglion cell layer
CD11c+ CD8 T cells cause IFN-γ-dependent autoimmune neuroinflammation that is restrained by PD-1 signaling
Study Overview This study explores the role of CD11c+ CD8 T cells in the development of autoimmune neuroinflammation, particularly focusing
Viral associations in multiple sclerosis: pathogenetic mechanisms and therapeutic implications
Viral Pathogens and Multiple Sclerosis Multiple sclerosis (MS) is often regarded as an autoimmune disorder where the immune system mistakenly
Age-related behavioral and molecular landmarks in new mouse models for studying Alzheimer’s disease in Down syndrome
Study Overview Research into the intricate relationship between Alzheimer’s disease (AD) and Down syndrome (DS) has gained momentum, particularly with