Stereotypies misdiagnosed as functional neurological disorder in late-onset Niemann-Pick C
Clinical Presentation of Niemann-Pick C Niemann-Pick disease type C (NPC) is a rare genetic disorder that primarily affects lipid metabolism […]
Diagnostic and therapeutic challenges in anti-NMDA receptor encephalitis associated with an ovarian immature teratoma
Pathophysiology of Anti-NMDA Receptor Encephalitis The condition known as anti-NMDA receptor encephalitis is regarded as a novel autoimmune encephalopathy, where
MicroRNA-mRNA Regulatory Network Associated with Cognitive Impairment in Multiple Sclerosis
MicroRNA-mRNA Interactions MicroRNAs (miRNAs) play a crucial role in the post-transcriptional regulation of gene expression, particularly in the context of
Beyond serology: clinical and prognostic determinants in patients with dual AQP4-IgG and MOG-IgG seropositivity
Study Overview The research investigates the clinical characteristics and outcomes associated with patients who have co-existing antibodies to aquaporin-4 (AQP4)
MicroRNA-mRNA Regulatory Network Associated with Cognitive Impairment in Multiple Sclerosis
MicroRNA-MRNA Interaction Dynamics MicroRNAs (miRNAs) are short, non-coding RNA molecules that play a crucial role in gene regulation by interacting
Raloxifene Beyond Osteoporosis: Unlocking Neurorestoration Through Remyelination, Inflammatory Regulation, and Neuroimmune Modulation in CNS Pathologies
Raloxifene Mechanisms in Neurorestoration Raloxifene, a selective estrogen receptor modulator (SERM), is primarily known for its role in the treatment
Dynamic metabolic programming of monocyte-derived cells defines immunity in CNS disease
Metabolic Programming in Monocyte-Derived Cells Monocyte-derived cells, particularly macrophages and dendritic cells, undergo a process termed metabolic programming, which significantly
Dynamic metabolic programming of monocyte-derived cells defines immunity in CNS disease Read Post »
Peripheral Neuropathy: A Phenotype-Driven Review for Diagnosis and Management
Phenotypic Classification of Peripheral Neuropathy Peripheral neuropathy encompasses a diverse range of conditions characterized by damage or dysfunction of the
Peripheral Neuropathy: A Phenotype-Driven Review for Diagnosis and Management Read Post »
Roles of Metformin and Pioglitazone in Regulating A1-like Astrocyte Activation in EAE Mice
Study Overview This investigation centers on the roles of two pharmacological agents, Metformin and Pioglitazone, in modulating the activation state
Purkinje cell-specific loss of Neurofascin and Ankyrin G causes disruption of axon initial segments, neurodegeneration, and cerebellar ataxia
Pathophysiological Mechanisms The pathophysiology underlying Purkinje cell-specific disruptions in neurofascin and ankyrin G reveals critical insights into the mechanisms that