A Bioinformatic Study of Genetics Involved in Determining Mild Traumatic Brain Injury Severity and Recovery
Genetic Factors in Traumatic Brain Injury Traumatic brain injury (TBI) can vary significantly in severity and impact from one individual […]
Neuron-derived extracellular vesicles reflect adaptive neuronal responses to cortical spreading depolarization: a biomarker study for migraine
Study Overview This study investigates the role of neuron-derived extracellular vesicles (EVs) in the context of cortical spreading depolarization (CSD),
Single-nucleus and spatial transcriptomic profiling of human temporal cortex and white matter reveals key associations with AD pathology
Study Overview This study centers on the intricate relationships between cellular profiles in the human brain’s temporal cortex and white
The kynurenine pathway in pediatric “mild-to-moderate” traumatic brain injury: translational insights from a prospective human study and a large-animal model
Kynurenine Pathway Mechanisms The kynurenine pathway is a critical metabolic route for the amino acid tryptophan, which leads to the
Targeted complement inhibition ameliorates the pathological and cognitive outcomes in repetitive mild closed head injury
Study Overview The investigation into the effects of targeted complement inhibition on outcomes following repetitive mild closed head injury is
Clinical Outcomes in the Patient With Traumatic Brain Injury and Comorbid Obesity: A Scoping Review
Clinical Outcomes in Traumatic Brain Injury Traumatic brain injury (TBI) represents a significant challenge in both acute medical care and
Long intervals between repetitive concussions reduce risk of cognitive impairment and limit microglial activation, astrogliosis, and tauopathy in adolescent rats
Impact of Concussion Intervals on Cognitive Outcomes Research indicates that the timing between concussive events significantly influences cognitive outcomes in
2Innate immune signaling mediates differential acute and long-term outcomes of repeated vs. single TBI in Drosophila
Study Overview The investigation centers around understanding how innate immune signaling influences the outcomes of traumatic brain injury (TBI) in
Biomarkers for prediction of chronic traumatic encephalopathy-like pathology following repeated mild traumatic brain injury in rats are partially sex- and age-dependent
Study Overview The research embarked on an investigation into the long-term effects of repeated mild traumatic brain injuries (mTBIs) and
Loss of C9orf72 impacts the peripheral neuromuscular system via immune dysregulation and accelerates the progression of amyotrophic lateral sclerosis in SOD-1 mutant mice
Impact of C9orf72 Loss on Neuromuscular Systems The loss of the C9orf72 gene has been identified as a significant factor