Study Overview The research focuses on investigating the effects of a novel NLRP3 inhibitor, AMS-17, …
Tag:
neuroinflammatory response
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Traumatic brain injury
Study of ubiquitin C-terminal hydrolase-L1, glial fibrillary acidic protein, and interleukin-6 levels in an experimental head trauma model in rabbits
by myneuronewsby myneuronewsStudy Overview This research investigates the roles of specific biomarkers—ubiquitin C-terminal hydrolase-L1 (UCH-L1), glial fibrillary …
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Traumatic brain injury
Study of ubiquitin C-terminal hydrolase-L1, glial fibrillary acidic protein, and interleukin-6 levels in an experimental head trauma model in rabbits
by myneuronewsby myneuronewsStudy Overview The investigation focused on analyzing the levels of ubiquitin C-terminal hydrolase-L1 (UCH-L1), glial …
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Traumatic brain injury
Repetitive mild traumatic brain injury with the closed-head impact model of engineered rotational acceleration (CHIMERA) promotes tau pathology in tau transgenic mice and its propagation in brains injected with tau fibrils
by myneuronewsby myneuronewsStudy Overview This study investigates the effects of repetitive mild traumatic brain injury (rmTBI) on …
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Traumatic brain injury
Relevance of cerebral microbleeds with leaky blood brain barrier in traumatic brain injury and protective role of interferon-gamma: A cohort study
by myneuronewsby myneuronewsStudy Overview This research focuses on the relationship between cerebral microbleeds, the integrity of the …
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Traumatic brain injury
Plasma biomarkers in chronic mild traumatic brain injury: A review
by myneuronewsby myneuronewsBiomarkers in Chronic Mild Traumatic Brain Injury Chronic mild traumatic brain injury (mTBI) is a …
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Dementia
Consideration of sex as a biological variable over the history of the 5xFAD Alzheimer’s Disease mouse model
by myneuronewsby myneuronewsBiological Considerations When investigating Alzheimer’s disease through animal models, particularly the 5xFAD mouse model, it …
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Traumatic brain injury
Development of a modified weight-drop apparatus for closed-skull, repetitive mild traumatic brain injuries in a mouse model
by myneuronewsby myneuronewsStudy Overview This research focuses on creating a refined apparatus designed to induce mild traumatic …
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Traumatic brain injury
The kynurenine pathway in pediatric “mild-to-moderate” traumatic brain injury: translational insights from a prospective human study and a large-animal model
by myneuronewsby myneuronewsKynurenine Pathway Mechanisms The kynurenine pathway is a critical metabolic route for the amino acid …
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Traumatic brain injury
Targeted complement inhibition ameliorates the pathological and cognitive outcomes in repetitive mild closed head injury
by myneuronewsby myneuronewsStudy Overview The investigation into the effects of targeted complement inhibition on outcomes following repetitive …