Tag:

neuroinflammatory response

Traumatic brain injury
Spautin-1 alleviates depression-like behaviors in mice after traumatic brain injury by inhibiting MMP3 expression in microglia in the Hippocampal CA1 region

by myneuronews September 12, 2025

by myneuronews September 12, 2025

Study Overview The research in question investigates the effects of Spautin-1, a compound known for …

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Functional neurological disorders
Somatic Symptom and Related Disorders and Mild Traumatic Brain Injury: A Systematic Review

by myneuronews September 2, 2025

by myneuronews September 2, 2025

Somatic Symptom Overview Somatic symptom disorders encompass a range of conditions characterized by the presence …

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Traumatic brain injury
Vibrational spectroscopy methods reveal biochemical changes associated with the glial scar formation after traumatic brain injury

by myneuronews August 9, 2025

by myneuronews August 9, 2025

Biochemical Changes in Glial Scarring After a traumatic brain injury (TBI), the central nervous system …

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Functional neurological disorders
Wogonin Inhibits Oxidative Stress in Hypoxia-Induced hCMEC/D3 Cells Through Suppressing CXCL8-Mediated TLR4/NF-κB Pathway

by myneuronews July 4, 2025

by myneuronews July 4, 2025

Mechanisms of Wogonin Action Wogonin, a naturally occurring flavonoid derived from the plant Scutellaria baicalensis, …

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Traumatic brain injury
Advances in Circulating Biomarkers for Neurodegenerative Diseases, Traumatic Brain Injuries, and Central Nervous System Tumors

by myneuronews June 18, 2025

by myneuronews June 18, 2025

Advancements in Biomarker Discovery Significant progress has been made in the realm of biomarker discovery, …

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Functional neurological disorders
Insights into insulin signalling and oxidative stress in the Tg2576 mouse model of familial Alzheimer’s disease: effects of chronic oral galactose administration

by myneuronews June 16, 2025

by myneuronews June 16, 2025

Insulin Signalling Pathways in Alzheimer’s Disease Insulin signalling pathways play a crucial role in numerous …

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Traumatic brain injury
Annual level changes of serum neuronal and glial biomarkers in a German professional football club

by myneuronews June 13, 2025

by myneuronews June 13, 2025

Study Overview The research centered on examining the variations in serum levels of neuronal and …

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Traumatic brain injury
Persistent Post-concussion syndrome: pathophysiology, diagnosis, current and evolving treatment strategies

by myneuronews June 7, 2025

by myneuronews June 7, 2025

Pathophysiology of Post-concussion Syndrome Post-concussion syndrome (PCS) is a complex disorder that can arise following …

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Traumatic brain injury
Single-nucleus and spatial signatures of the brainstem in normal brain and mild traumatic brain injury in male mice

by myneuronews May 31, 2025

by myneuronews May 31, 2025

Study Overview The research investigates the brainstem’s cellular and molecular properties in male mice, specifically …

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Functional neurological disorders
Association of APOC1 with cortical atrophy during conversion to Alzheimer’s disease

by myneuronews May 14, 2025

by myneuronews May 14, 2025

Association of Apolipoprotein C1 and Cognitive Decline The relationship between apolipoprotein C1 (APOC1) and cognitive …

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Severe Headache in a Child With Rickettsial Infection: A Case Report
Case Presentation A previously healthy 10-year-old boy was brought to the pediatric emergency department due…
Polygenic risk score of Alzheimer’s disease is associated with cognitive trajectories and phenotypes of cerebral organoids
Study Overview This study investigates the relationship between polygenic risk scores (PRS) for Alzheimer’s disease…
How Neurologists Combine Clinical Signs and Subjective Factors to Diagnose Epileptic and Functional Seizures: Insights From Seizure Video Analysis
Diagnostic Approaches in Epilepsy and Seizures The diagnosis of epilepsy and seizures is a complex…
Active Rehabilitation Following Acute Mild Traumatic Brain Injury: A Systematic Review
Active Rehabilitation Approaches Active rehabilitation is a crucial component in the recovery process following an…
Connecting the Dots: The Role of Pediatric Concussion on Pubertal Hormones and Psychological Health
Pediatric Concussions: Overview and Impact Pediatric concussions are a significant public health concern, with increasing…

The cumulative effects of a collegiate athletic career on general health measures: findings from the CARE Consortium
CONCLUSIONS: Lifetime concussion history is associated with self-reported health outcomes at institutional-exit, though small effect sizes suggest limited clinical consequence. Higher contact-exposure sports and increased YoP were associated with improved scores on some clinical measures. Further longitudinal monitoring is encouraged to evaluate health-related changes over time, to support student-athletes as they transition out of collegiate […]
Symptoms of Allodynia and Pain Thresholds Amongst Those with Acute Post-Traumatic Headache Attributed to Mild Traumatic Brain Injury: A Prospective, Longitudinal Study
Background Post-traumatic headache (PTH) is a common acute and persistent symptom following mild traumatic brain injury (mTBI). Symptoms of cutaneous allodynia and presence of nociceptive sensitization might be associated with acute PTH and its persistence. The objectives of this study were to compare allodynia symptoms and cutaneous heat pain thresholds amongst males and females with […]
Efficacy of Methylphenidate in Patients With Brain Disease: A Systematic Review and Meta-Analysis
This systematic review and meta-analysis evaluated the efficacy and safety of methylphenidate in patients with brain disease. A comprehensive search up to November 4, 2024 identified 33 randomized controlled trials involving 1,369 participants with traumatic brain injury (TBI), stroke, Parkinson's disease (PD), Alzheimer's disease (AD), other dementias, and multiple sclerosis. Methylphenidate was administered at 10-80 […]
Blast-Related Mild Traumatic Brain Injury: Case Report Highlighting the Long-Term Neurocognitive Sequelae Following Blast Exposure in Veterans
Traumatic brain injury (TBI) remains a significant public health concern, particularly among military service members exposed to blast-related trauma. While mild TBIs often resolve within weeks, a subset of patients may experience lifelong, persistent, debilitating symptoms. We report a case of a previously healthy male combat medic who sustained a blast-related traumatic brain injury during […]
Smooth Pursuit Velocity After a Season of Repetitive Head Impacts in American Football Players
CONCLUSIONS AND RELEVANCE: In this study, smooth pursuit eye movement velocity was not affected during a single season of contact sports. Group differences suggest existing deficits before the season begins, possibly due to prior contact sport history. Interpretations should be tempered by the small sample size, single institution used for data collection, and the exploratory […]