Tag:

neuroinflammatory response

Dementia
Consideration of sex as a biological variable over the history of the 5xFAD Alzheimer’s Disease mouse model

by myneuronews December 17, 2025

by myneuronews December 17, 2025

Biological Considerations When investigating Alzheimer’s disease through animal models, particularly the 5xFAD mouse model, it …

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Traumatic brain injury
Development of a modified weight-drop apparatus for closed-skull, repetitive mild traumatic brain injuries in a mouse model

by myneuronews December 4, 2025

by myneuronews December 4, 2025

Study Overview This research focuses on creating a refined apparatus designed to induce mild traumatic …

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Traumatic brain injury
The kynurenine pathway in pediatric “mild-to-moderate” traumatic brain injury: translational insights from a prospective human study and a large-animal model

by myneuronews November 21, 2025

by myneuronews November 21, 2025

Kynurenine Pathway Mechanisms The kynurenine pathway is a critical metabolic route for the amino acid …

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Traumatic brain injury
Targeted complement inhibition ameliorates the pathological and cognitive outcomes in repetitive mild closed head injury

by myneuronews November 19, 2025

by myneuronews November 19, 2025

Study Overview The investigation into the effects of targeted complement inhibition on outcomes following repetitive …

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Dementia
Loss of C9orf72 impacts the peripheral neuromuscular system via immune dysregulation and accelerates the progression of amyotrophic lateral sclerosis in SOD-1 mutant mice

by myneuronews November 15, 2025

by myneuronews November 15, 2025

Impact of C9orf72 Loss on Neuromuscular Systems The loss of the C9orf72 gene has been …

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Traumatic brain injury
Therapeutic VEGFC treatment provides protection against traumatic-brain-injury-driven tauopathy pathogenesis

by myneuronews November 8, 2025

by myneuronews November 8, 2025

Therapeutic Efficacy of VEGFC The treatment of traumatic brain injury (TBI) has been a significant …

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Traumatic brain injury
Evolution of Axonal Injury in the Closed Head Impact Model of Engineered Rotational Acceleration in Adult Ferrets

by myneuronews October 30, 2025

by myneuronews October 30, 2025

Study Overview This research examines the impact of engineered rotational acceleration on axonal injury in …

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Traumatic brain injury
Changes in peripheral blood and cognitive performance after nonconcussive head impacts in elite female soccer players

by myneuronews October 7, 2025

by myneuronews October 7, 2025

Study Overview The research investigates the effects of nonconcussive head impacts on both the peripheral …

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Traumatic brain injury
Spautin-1 alleviates depression-like behaviors in mice after traumatic brain injury by inhibiting MMP3 expression in microglia in the Hippocampal CA1 region

by myneuronews September 12, 2025

by myneuronews September 12, 2025

Study Overview The research in question investigates the effects of Spautin-1, a compound known for …

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Functional neurological disorders
Somatic Symptom and Related Disorders and Mild Traumatic Brain Injury: A Systematic Review

by myneuronews September 2, 2025

by myneuronews September 2, 2025

Somatic Symptom Overview Somatic symptom disorders encompass a range of conditions characterized by the presence …

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Morning sleep inertia and its associated factors: Findings from a nationwide study
Understanding Sleep Inertia Sleep inertia refers to the temporary state of cognitive and physical impairment…
Association between late-life air pollution exposure and medial temporal lobe atrophy in older women
Study Overview The research focuses on the potential relationship between exposure to air pollution in…
From Code Stroke to Cultural Formulation: A Case of Postpartum Functional Neurologic Disorder
Understanding Postpartum Functional Neurologic Disorder Postpartum Functional Neurologic Disorder (FND) represents a complex intersection between…
Video Assessment of the Frequency and Evaluations of Head Collision Events During the 2022 World Cup
Frequency of Head Collisions In the context of the 2022 World Cup, the frequency of…
Platforms to Evaluate Flavivirus-Induced Immunoinflammatory Responses and Their Pathogenesis
Overview of Flavivirus Pathogenesis Flaviviruses, a diverse group of RNA viruses, are known to cause…

Language biomarker screening using AI: a transdiagnostic approach to brain
Individuals with left-hemisphere damage (LHD), right-hemisphere damage (RHD), dementia, mild cognitive impairment (MCI), traumatic brain injury (TBI), and healthy controls are characterized by overlapping clinical profiles affecting communication and social interaction. Language provides a rich, non-invasive window into neurological health, yet objective and scalable methods to automatically differentiate between conditions with are lacking. This method […]
Video Assessment of the Frequency and Evaluations of Head Collision Events During the 2022 World Cup
CONCLUSIONS: The results of this study suggest that progress has been made to properly evaluate and recognize concussions; however, further attention is clearly still required to ensure the health and safety of international soccer players.
Enhancing Outpatient Clinic Recruitment: A Quality Improvement Strategy for a Prospective Research Study
CONCLUSIONS: This project demonstrates the successful application of quality improvement methodology toward optimizing clinical recruitment. Approaches used in this study can potentially be generalized to other outpatient clinical populations and research studies.
Driving After Concussion: Clinical Measures Associated With Postconcussion Driving
CONCLUSIONS: Dual-task and Complex Figure tests might be useful when assessing postconcussion driving ability. Higher VOMS symptom provocation was associated with better driving performance, possibly indicating that individuals experiencing vestibular-oculomotor symptoms may adopt more cautious strategies.
Health Literacy Among Adolescent Athletes Across Rural and Urban Communities and Evaluating Scores Aside State-Mandated Concussion Education
CONCLUSIONS: Urban adolescent athletes had better health literacy compared with their rural peers; however, irrespective of rurality, more than half of participants had low health literacy for their appropriate age/grade in high school (≤seventh grade). Ensuring that health information is provided at an appropriate reading level for the target audience is essential to increasing health […]