Tag:

neuroinflammatory response

Traumatic brain injury
Therapeutic VEGFC treatment provides protection against traumatic-brain-injury-driven tauopathy pathogenesis

by myneuronews November 8, 2025

by myneuronews November 8, 2025

Therapeutic Efficacy of VEGFC The treatment of traumatic brain injury (TBI) has been a significant …

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Traumatic brain injury
Evolution of Axonal Injury in the Closed Head Impact Model of Engineered Rotational Acceleration in Adult Ferrets

by myneuronews October 30, 2025

by myneuronews October 30, 2025

Study Overview This research examines the impact of engineered rotational acceleration on axonal injury in …

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Traumatic brain injury
Changes in peripheral blood and cognitive performance after nonconcussive head impacts in elite female soccer players

by myneuronews October 7, 2025

by myneuronews October 7, 2025

Study Overview The research investigates the effects of nonconcussive head impacts on both the peripheral …

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Traumatic brain injury
Spautin-1 alleviates depression-like behaviors in mice after traumatic brain injury by inhibiting MMP3 expression in microglia in the Hippocampal CA1 region

by myneuronews September 12, 2025

by myneuronews September 12, 2025

Study Overview The research in question investigates the effects of Spautin-1, a compound known for …

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Functional neurological disorders
Somatic Symptom and Related Disorders and Mild Traumatic Brain Injury: A Systematic Review

by myneuronews September 2, 2025

by myneuronews September 2, 2025

Somatic Symptom Overview Somatic symptom disorders encompass a range of conditions characterized by the presence …

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Traumatic brain injury
Vibrational spectroscopy methods reveal biochemical changes associated with the glial scar formation after traumatic brain injury

by myneuronews August 9, 2025

by myneuronews August 9, 2025

Biochemical Changes in Glial Scarring After a traumatic brain injury (TBI), the central nervous system …

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Functional neurological disorders
Wogonin Inhibits Oxidative Stress in Hypoxia-Induced hCMEC/D3 Cells Through Suppressing CXCL8-Mediated TLR4/NF-κB Pathway

by myneuronews July 4, 2025

by myneuronews July 4, 2025

Mechanisms of Wogonin Action Wogonin, a naturally occurring flavonoid derived from the plant Scutellaria baicalensis, …

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Traumatic brain injury
Advances in Circulating Biomarkers for Neurodegenerative Diseases, Traumatic Brain Injuries, and Central Nervous System Tumors

by myneuronews June 18, 2025

by myneuronews June 18, 2025

Advancements in Biomarker Discovery Significant progress has been made in the realm of biomarker discovery, …

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Functional neurological disorders
Insights into insulin signalling and oxidative stress in the Tg2576 mouse model of familial Alzheimer’s disease: effects of chronic oral galactose administration

by myneuronews June 16, 2025

by myneuronews June 16, 2025

Insulin Signalling Pathways in Alzheimer’s Disease Insulin signalling pathways play a crucial role in numerous …

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Traumatic brain injury
Annual level changes of serum neuronal and glial biomarkers in a German professional football club

by myneuronews June 13, 2025

by myneuronews June 13, 2025

Study Overview The research centered on examining the variations in serum levels of neuronal and …

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Prevalence of depression, anxiety, fatigue, and headache before and after long COVID onset: a case-control study in the total population of Region Stockholm
Study Overview The investigation centered on the prevalence rates of common mental and physical health…
Dynamic functional connectivity and transcriptomic signatures reveal stage-dependent brain network dysfunction in Alzheimer’s disease spectrum
Study Overview The research focused on understanding the intricate relationship between brain network connectivity and…
Multisite, Multiancestry Genome-Wide Association Study Meta-Analysis of Functional Seizure Disorder in a Hospital Sample of 675,680 Patients
Study Summary The recent study presents an extensive analysis of functional seizure disorder, conducted through…
Phenotyping Functional Gait Disorder: An Exploratory Analysis of Existing Frameworks
Phenotyping Functional Gait Disorder Functional Gait Disorder (FGD) represents a unique challenge in the field…
Diagnosis and treatment of functional visual disorder
Understanding Functional Visual Disorder Functional Visual Disorder (FVD) is a condition that presents a unique…

Profiles of cold executive function performance among pediatric acquired brain injury
CONCLUSIONS: Distinct executive function profiles were observed across ABI subtypes, with PAS associated with the most pervasive impairments, TBI with selective deficits, and BT with targeted planning difficulties. These findings highlight the importance of tailored cognitive rehabilitation strategies based on ABI subtype.
Longitudinal neurocognitive outcomes in children with mild traumatic brain injury: An ABCD cohort analysis
CONCLUSIONS: The findings highlight the importance of accounting for pre-injury differences when evaluating neurocognitive outcomes following pediatric mTBI. Neurocognitive differences within a year post-injury may be more related to pre-existing individual factors rather than the injury itself, underscoring the need for a comprehensive approach in studying pediatric mTBI.
Fear Avoidance after Concussion Tool (FACT): patient-reported outcome measure development and content validation
CONCLUSION: The FACT has been developed to evaluate fear avoidance behaviour following concussion and has content validity. Future research should evaluate other measurement properties before implementation.
Spare the brain: female football players' perspectives of heading the ball, concussion knowledge and attitudes. A qualitative study
The aim of this study was to explore female football (soccer) players' perspectives of heading the ball, and perceived header injury risk. A qualitative approach was undertaken using reflexive thematic analysis. Focus groups and individual interviews were conducted using a semi-structured interview guide. Participants also completed a survey containing a validated concussion knowledge and attitudes […]
Metabolomics of cerebrospinal fluid following traumatic brain injury: Exploration of biomarkers for secondary injuries and severity
Traumatic brain injury (TBI) constitutes a major global public health concern associated with substantial mortality and long-term disability, while its diagnostic approaches and underlying pathophysiological mechanisms remain to be fully elucidated. In this study, we conducted longitudinal metabolomic profiling of cerebrospinal fluid (CSF) from 23 TBI patients (9 mild, 14 severe) and 5 uninjured controls […]