Tag:

neuroinflammatory response

Traumatic brain injury
Development of a modified weight-drop apparatus for closed-skull, repetitive mild traumatic brain injuries in a mouse model

by myneuronews December 4, 2025

by myneuronews December 4, 2025

Study Overview This research focuses on creating a refined apparatus designed to induce mild traumatic …

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Traumatic brain injury
The kynurenine pathway in pediatric “mild-to-moderate” traumatic brain injury: translational insights from a prospective human study and a large-animal model

by myneuronews November 21, 2025

by myneuronews November 21, 2025

Kynurenine Pathway Mechanisms The kynurenine pathway is a critical metabolic route for the amino acid …

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Traumatic brain injury
Targeted complement inhibition ameliorates the pathological and cognitive outcomes in repetitive mild closed head injury

by myneuronews November 19, 2025

by myneuronews November 19, 2025

Study Overview The investigation into the effects of targeted complement inhibition on outcomes following repetitive …

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Dementia
Loss of C9orf72 impacts the peripheral neuromuscular system via immune dysregulation and accelerates the progression of amyotrophic lateral sclerosis in SOD-1 mutant mice

by myneuronews November 15, 2025

by myneuronews November 15, 2025

Impact of C9orf72 Loss on Neuromuscular Systems The loss of the C9orf72 gene has been …

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Traumatic brain injury
Therapeutic VEGFC treatment provides protection against traumatic-brain-injury-driven tauopathy pathogenesis

by myneuronews November 8, 2025

by myneuronews November 8, 2025

Therapeutic Efficacy of VEGFC The treatment of traumatic brain injury (TBI) has been a significant …

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Traumatic brain injury
Evolution of Axonal Injury in the Closed Head Impact Model of Engineered Rotational Acceleration in Adult Ferrets

by myneuronews October 30, 2025

by myneuronews October 30, 2025

Study Overview This research examines the impact of engineered rotational acceleration on axonal injury in …

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Traumatic brain injury
Changes in peripheral blood and cognitive performance after nonconcussive head impacts in elite female soccer players

by myneuronews October 7, 2025

by myneuronews October 7, 2025

Study Overview The research investigates the effects of nonconcussive head impacts on both the peripheral …

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Traumatic brain injury
Spautin-1 alleviates depression-like behaviors in mice after traumatic brain injury by inhibiting MMP3 expression in microglia in the Hippocampal CA1 region

by myneuronews September 12, 2025

by myneuronews September 12, 2025

Study Overview The research in question investigates the effects of Spautin-1, a compound known for …

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Functional neurological disorders
Somatic Symptom and Related Disorders and Mild Traumatic Brain Injury: A Systematic Review

by myneuronews September 2, 2025

by myneuronews September 2, 2025

Somatic Symptom Overview Somatic symptom disorders encompass a range of conditions characterized by the presence …

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Traumatic brain injury
Vibrational spectroscopy methods reveal biochemical changes associated with the glial scar formation after traumatic brain injury

by myneuronews August 9, 2025

by myneuronews August 9, 2025

Biochemical Changes in Glial Scarring After a traumatic brain injury (TBI), the central nervous system …

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Efficacy and safety of relugolix therapy for symptomatic uterine fibroids: a systematic review and meta-analysis
Efficacy of Relugolix Relugolix, an oral gonadotropin-releasing hormone (GnRH) antagonist, has demonstrated notable efficacy in…
Disclosure of onset-predictive biomarker results to research participants at risk of genetic frontotemporal dementia: a European perspective
Background on Genetic Frontotemporal Dementia Genetic frontotemporal dementia (FTD) is a group of neurodegenerative disorders…
DCPat-XFE: an explainable EEG model for psychogenic nonepileptic seizure detection
Study Summary The study presents the DCPat-XFE model, designed to enhance the detection of psychogenic…
Prevalence of Vestibular Disorders in Moderate-Severe Traumatic Brain Injury (TBI): A Scoping Review
Study Overview The focus of this scoping review is to explore the prevalence of vestibular…
Association of sports and physical activity with mild traumatic brain injury and behavioral and neurocognitive function
Study Overview The article investigates the relationship between engagement in sports and physical activities and…

Prevalence of Vestibular Disorders in Moderate-Severe Traumatic Brain Injury (TBI): A Scoping Review
CONCLUSION: Vestibular dysfunction is prevalent among individuals with moderate-to-severe TBI, although the methods of assessment vary. Future studies should aim to be more consistent in documenting the severity of TBI, the evaluation of vestibular dysfunction, and determining interventions that are most beneficial for this population.
Association of sports and physical activity with mild traumatic brain injury and behavioral and neurocognitive function
CONCLUSION: Participation in soccer and/or climbing showed positive associations with mTBI, while participation in yoga showed a negative association. Sports/PA participation was related to better behavioral/emotional and neurocognitive functioning, regardless of children's injury history.
Educational Perspectives on Compassionate Concussion Care: A Scoping Review
CONCLUSION: This review highlights the implicit paradigms shaping concussion-care education and their limitations for cultivating compassion. Constructivism offers the most promise for advancing compassionate practice by fostering collaboration, reflection, and learner agency. Given the interpersonal, cognitive and contextual demands of concussion care, adopting a constructivist orientation may better prepare physicians to meet patient and caregiver […]
A challenge to improve the Quality of Care.Rehabilitation outcome measures in the Emergency Department: a scoping review
CONCLUSIONS: The use of validated outcome measures by physiotherapists in EDs is feasible and clinically valuable; however, a lack of standardization and limited high-quality evidence particularly within the Italian healthcare context highlight the need for further research to establish shared outcome sets and transferable models of care.
Gaps in Access to Cognitive Rehabilitation Referrals Among Veterans with Mild Traumatic Brain Injury
CONCLUSIONS: These results suggest that while cognitive rehabilitation services tend to be allocated to those in need, significant gaps in access exist. Findings lay the foundation for developing strategies that expand access to beneficial cognitive rehabilitation among Veterans with mTBI, reducing their cognitive symptoms and enhancing their daily function.