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neurological diseases

Functional neurological disorders
Changes in brain functional connectivity and clinical correlations in neuromyelitis optica spectrum disorder: a longitudinal resting-state fMRI study

by myneuronews May 20, 2025

by myneuronews May 20, 2025

Overview of Neuromyelitis Optica Spectrum Disorder Neuromyelitis Optica Spectrum Disorder (NMOSD) is a rare, autoimmune …

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Functional neurological disorders
Multiple system biology approaches reveals the role of the hsa-miR-21 in increasing risk of neurological disorders in patients suffering from hypertension

by myneuronews May 19, 2025

by myneuronews May 19, 2025

Role of hsa-miR-21 in Neurological Disorders The study investigates the important role of hsa-miR-21, a …

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Functional neurological disorders
Electrophysiological characterisation of intranigral-grafted hiPSC-derived dopaminergic neurons in a mouse model of Parkinson’s disease

by myneuronews May 9, 2025

by myneuronews May 9, 2025

Electrophysiological Properties of hiPSC-Derived Neurons The study begins by examining the electrophysiological properties of human-induced …

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Functional neurological disorders
GWAS by Subtraction to Disentangle RBD Genetic Background from α-Synucleinopathies

by myneuronews May 7, 2025

by myneuronews May 7, 2025

Background and Rationale The study of genetic factors influencing neurological conditions has gained momentum in …

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Functional neurological disorders
Cholinergic degeneration in prodromal and early Parkinson’s: a link to present and future disease states

by myneuronews May 6, 2025

by myneuronews May 6, 2025

Cholinergic System Dysfunction in Parkinson’s The cholinergic system plays a critical role in various brain …

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Stroke
Exosome-powered neuropharmaceutics: unlocking the blood-brain barrier for next-gen therapies

by myneuronews May 3, 2025

by myneuronews May 3, 2025

Exosome Technology in Neuropharmaceutics Exosomes represent a groundbreaking advancement in the field of neuropharmaceutics, offering …

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Functional neurological disorders
Brain-wide microglia replacement using a nonconditioning strategy ameliorates pathology in mouse models of neurological disorders

by myneuronews April 30, 2025

by myneuronews April 30, 2025

Microglia Replacement Strategy The study introduces an innovative approach to addressing neurological disorders through the …

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Functional neurological disorders
Regulation of chronic neuroinflammation through dietary herbal products

by myneuronews April 29, 2025

by myneuronews April 29, 2025

Role of Dietary Herbal Products in Neuroinflammation Dietary herbal products have garnered significant interest in …

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Medical professionals Traumatic brain injury
Unlocking the Molecular Secrets of Traumatic Brain Injury: A Path Toward Innovative Diagnostics and Therapies

by Ioannis Mavroudis March 22, 2024

by Ioannis Mavroudis March 22, 2024

Unlocking the Molecular Secrets of Traumatic Brain Injury: A Path Toward Innovative Diagnostics and Therapies

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Altered autonomic cardiovascular function in adults with persisting post-concussive symptoms and exercise intolerance
Alterations in autonomic cardiovascular function may result following mild traumatic brain injury (mTBI), but there is a lack of data evaluating autonomic function in adults with persisting post-concussive symptoms (PPCS). We collected resting measures of heart rate (HR), heart rate variability (HRV), blood pressure (BP) and cardiac baroreceptor sensitivity in 50 adults with PPCS (42.8 […]
Influence of Social Determinants of Health on Treatment Completion for Pediatric Mild Traumatic Brain Injury in a Safety Net Hospital
The negative impact of the Social Determinants of Health (SDOH) on health care outcomes in vulnerable populations, particularly pediatric patients, is a well-established phenomenon. The treatment of traumatic brain injury is not an exception. It is not clear, however, which specific social determinants of health factor is more influential on the current management of traumatic […]
Inhibition of p38 MAPK after repetitive mild TBI ameliorates immune signaling and behavioral deficits
BACKGROUND: Mild traumatic brain injury (mTBI) can cause long-term functional impairments, and repetitive mTBIs within a window of vulnerability can exacerbate these consequences compared to a single mTBI. However, current interventions for mTBI focus on alleviating symptoms, rather than targeting underlying mechanisms. Following the initial mechanical impact, increasing evidence suggests that the brain undergoes an […]
Comparison of Machine Learning Models in Predicting Mental Health Sequelae Following Concussion in Youth
Youth who experience concussions may be at greater risk for subsequent mental health challenges, making early detection crucial for timely intervention. This study utilized Bidirectional Long Short-Term Memory (BiLSTM) networks to predict mental health outcomes following concussion in youth and compared its performance to traditional models. We also examined whether incorporating social determinants of health […]
Comparing Single-Site Fractures with Multisite Injuries in Pediatric Skiers and Snowboarders
Introduction-The purpose of this study was to evaluate pediatric skiing and snowboarding fracture injuries at a large ski resort, comparing injury patterns in those who sustained fracture injuries at a single site against those with injuries in multiple sites. Given the more serious nature of multisite injuries, this information may give healthcare providers insight into […]