Tag:

neurological disorders

Functional neurological disorders
Development of a novel liquid chromatography-tandem mass spectrometry based enzymatic assay of 5,10-methylenetetrahydrofolate reductase

by myneuronews July 2, 2025

by myneuronews July 2, 2025

Enzymatic Assay Development The development of a novel enzymatic assay for 5,10-methylenetetrahydrofolate reductase (MTHFR) taps …

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Traumatic brain injury
Brain health concerns in former rugby players: clinical and cognitive phenotypes

by myneuronews July 2, 2025

by myneuronews July 2, 2025

Context of Brain Health in Rugby The discussion around brain health in former rugby players …

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Traumatic brain injury
Long-Term Health-Related Quality of Life and Perceptions of Recovery in Adults Who Received Clinical Profiles Informed Care for Concussion

by myneuronews July 2, 2025

by myneuronews July 2, 2025

Long-Term Quality of Life Outcomes Long-term health-related quality of life (HRQoL) outcomes for adults who …

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Functional neurological disorders
Association of Striatal Dopaminergic Depletion and Cerebral Perfusion With Cognition in Brain-First and Body-First Parkinson’s Disease

by myneuronews June 30, 2025

by myneuronews June 30, 2025

Dopaminergic Depletion and Cognition Dopaminergic depletion in the striatum is a critical factor in understanding …

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Traumatic brain injury
Differential DNA Methylation of the Brain-Derived Neurotrophic Factor Gene is Observed after Pediatric Traumatic Brain Injury Compared to Orthopedic Injury

by myneuronews June 30, 2025

by myneuronews June 30, 2025

Study Overview The study investigates the differential methylation patterns of the brain-derived neurotrophic factor (BDNF) …

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Traumatic brain injury
Adaptive trial for the treatment of depressive symptoms associated with concussion using accelerated intermittent theta burst stimulation (ADEPT): rationale, design and methods

by myneuronews June 30, 2025

by myneuronews June 30, 2025

Study Overview The ADEPT trial is designed to investigate the effectiveness of accelerated intermittent theta …

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Traumatic brain injury
Microstructural Damage Progression in the Pia-Arachnoid Complex

by myneuronews June 29, 2025

by myneuronews June 29, 2025

Microstructural Changes Observed The study of microstructural changes within the pia-arachnoid complex reveals a complex …

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Functional neurological disorders
Mental disorders in military personnel at the stage of medical care in a multidisciplinary military medical organization

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Mental Health Challenges in Military Personnel Mental health challenges among military personnel are significant and …

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Functional neurological disorders
Myeloproliferative syndrome as a cause of chorea

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Myeloproliferative Syndrome Overview Myeloproliferative syndromes (MPS) are a group of blood disorders characterized by the …

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Functional neurological disorders
Modulation of conformational features and oligomerization of MMACHC by cobalamin variants: impact of the R161Q mutation in cblC disease

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Modulation of MMACHC Conformational Features Recent investigations into the MMACHC protein have revealed that its …

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Acute effects of sport-related concussion among adolescents with a self-reported history of treatment for anxiety or depression
Objective: This study compared symptom reporting and cognitive test performance within 72 h of a suspected concussion between high school student-athletes with and without pre-injury self-reported mental health treatment. Methods: Eight hundred seventy-nine high school athletes with (n = 75) and without (n = 804) a self-reported history of treatment for anxiety or depression underwent […]
Boston University Alzheimer's Disease Research Center Clinical Core: Infrastructure to facilitate research on post-traumatic Alzheimer's disease and related dementias
We describe the rationale, methodology, and design of the Boston University Alzheimer's Disease Research Center (BU ADRC) Clinical Core (CC). The CC characterizes a longitudinal cohort of participants with/without brain trauma to characterize the clinical presentation, biomarker profiles, and risk factors of post-traumatic Alzheimer's disease (AD) and AD-related dementias (ADRD), including chronic traumatic encephalopathy (CTE). […]
Examining for race-associated differences on Sway Medical System balance and cognitive tests used for sport-related concussion
CONCLUSION: The race-associated differences between Black and White student-athletes on Sway Medical System balance and cognitive module scores are generally negligible. The reasons for modest race-associated differences on Memory scores are unknown and future research to examine the possible role or influence of social risk factors and psychosocial factors on module scores is recommended.
Effects of Lifetime Exposure to Sports-Related Head Impacts on Brain Injury and Inflammatory Blood Biomarkers Among Former Middle-Aged Athletes
Repetitive head impacts from contact sports are associated with an increased risk of neurodegenerative conditions. While studies have examined acute and chronic outcomes in young and deceased athletes, research on middle-aged former athletes remains limited. We employed multiplex biomarker approaches to examine whether brain injury and systemic inflammatory blood biomarkers are reflective of ≥10 years […]
Pain Management Strategies and Adverse Effects of Opioids in Patients with Neurotrauma with Acute and Chronic Pain
Pain is prevalent and a major source of disability after a traumatic brain injury (TBI) and a spinal cord injury (SCI). With a view of reducing the pain burden in neurotrauma, this study aimed to describe the use of pain management strategies and the adverse effects of opioids in patients with TBI and SCI. We […]