Tag:

neurology

Functional neurological disorders
Clinically Accurate Diagnosis of Alzheimer’s Disease via Single-Molecule Bioelectronic Label-Free Profiling of Multiple Blood Extracellular Vesicle Biomarkers

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Overview of Bioelectronic Profiling Techniques Bioelectronic profiling has emerged as a revolutionary approach for the …

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Functional neurological disorders
Lesion distribution and network mapping in dyskinetic cerebral palsy

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Lesion Characteristics in Dyskinetic Cerebral Palsy In dyskinetic cerebral palsy, the distribution of lesions is …

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Traumatic brain injury
Distinct clinical phenotypes and their neuroanatomic correlates in chronic traumatic brain injury

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Clinical Phenotypes In chronic traumatic brain injury (TBI), individuals often manifest a variety of clinical …

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Traumatic brain injury
Association between concomitant traumatic brain injury and unfavorable 1-year outcomes in patients with traumatic spinal cord injury

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Study Overview The investigation centered around the relationship between traumatic brain injury (TBI) and the …

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Functional neurological disorders
Comparative effects of sensory motor and virtual reality interventions to improve gait, balance and quality of life MS patients

by myneuronews June 26, 2025

by myneuronews June 26, 2025

Comparative Analysis of Interventions The study provides a thorough comparative analysis of two prominent therapeutic …

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Functional neurological disorders
Correlation of Positive Signs of Functional Neurological Disorder With Headache Severity: A Prospective Cross-Sectional Study

by myneuronews June 26, 2025

by myneuronews June 26, 2025

Background on Functional Neurological Disorder Functional Neurological Disorder (FND) is a complex and often misunderstood …

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Functional neurological disorders
Comparing Injection Methods of Botulinum Toxin A for Cervical Dystonia: A Systematic Review

by myneuronews June 26, 2025

by myneuronews June 26, 2025

Overview of Botulinum Toxin A Botulinum Toxin A (BoNT-A) has emerged as a groundbreaking therapeutic …

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Functional neurological disorders
The Incidence of Misdiagnosis in Patients with Ehlers-Danlos Syndrome

by myneuronews June 26, 2025

by myneuronews June 26, 2025

Prevalence of Misdiagnosis in Ehlers-Danlos Syndrome Recent studies have illuminated a concerning trend regarding the …

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Functional neurological disorders
Circulating inflammatory proteins as pathogenic mediators and potential therapeutic targets in myasthenia gravis

by myneuronews June 26, 2025

by myneuronews June 26, 2025

Pathogenesis of Myasthenia Gravis Myasthenia Gravis (MG) is an autoimmune disorder characterized by weakness and …

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Functional neurological disorders
Correlation of Positive Signs of Functional Neurological Disorder With Headache Severity: A Prospective Cross-Sectional Study

by myneuronews June 26, 2025

by myneuronews June 26, 2025

Overview of Functional Neurological Disorder Functional Neurological Disorder (FND) is recognized as a complex condition …

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Decreased IL-33 in the brain following repetitive mild traumatic brain injury contributes to cognitive impairment by inhibiting microglial phagocytosis
CONCLUSIONS: Dysfunction of the IL-33/ST2 axis following rmTBI leads to cognitive dysfunction via impairing microglial phagocytosis capacity and promoting neuronal damage. IL-33 would be a promising therapeutic target for alleviating neurodegeneration following rmTBI.
Multidisciplinary rehabilitation and follow-up for children hospitalized with traumatic brain injury
PurposeMost children hospitalized with traumatic brain injury (TBI) acquire new impairments that impact function and health-related quality of life. However, there is a lack of standardized, multidisciplinary, longitudinal rehabilitative services for children with TBI.MethodsThis single center, retrospective study evaluated rehabilitative services during acute hospitalization and identified the frequency of unmet needs, defined as new or […]
Tackle characteristics associated with concussion in elite men's rugby union: unpicking the differences between tacklers and ball-carriers
CONCLUSIONS: Lower tackles reduce the chances of concussion to ball-carriers. The influence of tackle height on concussion to tacklers is more nuanced, but the chances are relatively low when contact is made with the ball-carrier's torso. These findings support ongoing implementation of strategies to reduce concussion risk by lowering tackle height to target the torso.
Development of a modified weight-drop apparatus for closed-skull, repetitive mild traumatic brain injuries in a mouse model
Repetitive mild traumatic brain injury (rmTBI) is a major contributor to long-term neurological dysfunction, yet many preclinical models lack precise control and quantification of biomechanical forces across impacts. We developed a reproducible, closed-skull mouse model of rmTBI using a custom-built weight-drop apparatus featuring a solenoid-based rebound arrest system, integrated high-speed videography, and accelerometry to track […]
Pretreatment with an anti-CGRP monoclonal antibody attenuates mild TBI-induced tactile hypersensitivity in mice
CONCLUSIONS: These results indicate that an anti-CGRP mAb can partially, but not fully, attenuate cephalic tactile hypersensitivity when administered immediately before or after the mTBI event. In contrast, a stronger rescue was seen when the anti-CGRP mAb was administered just prior to CGRP and nitric oxide triggers. Thus, depending on the timing of administration, the […]