Reprogramming immunity: the promise and challenges of CAR T cell therapy in multiple sclerosis
Therapeutic Mechanisms The therapeutic mechanisms of CAR T cell therapy revolve around its innovative approach to manipulating the immune system. […]
Myelin debris uptake by macrophages and microglia: Resolution of foam cells with a series of novel cyclodextrins
Study Overview This research investigates the role of macrophages and microglia in the phagocytosis of myelin debris, a process critical
Microbial modulation of CNS remyelination in multiple sclerosis: the missing link in gut-brain axis research
Microbial Influence on CNS Health The central nervous system (CNS) is not an isolated entity; it interacts closely with the
Electrophysiology in Distinguishing Functional Tremor from Organic Tremor: A Systematic Review and Meta-Analysis of Diagnostic Accuracy
Study Overview The recent systematic review and meta-analysis focused on the role of electrophysiological assessments in differentiating functional tremors from
Psilocybin restores behavior and 5-HT(2A) signaling while reducing microglial density after chronic traumatic brain injury in rats
Study Overview The research investigated the effects of psilocybin, a compound derived from certain mushrooms, on rats that had suffered
Age- and Sex-Related Differences in GFAP and UCH-L1 Levels in Mild Traumatic Brain Injury
Study Overview This research investigates how age and sex influence the levels of glial fibrillary acidic protein (GFAP) and ubiquitin
Long-term visual outcomes and treatment-related prognostic variables in pediatric demyelinating optic neuritis: A 10-year retrospective cohort study
Pediatric demyelinating optic neuritis Demyelinating optic neuritis in children represents a significant concern within pediatric neurology and ophthalmology, often serving
Pro-repair properties of a human embryonic stem cell-derived astrocyte cell therapy in demyelinating disorders
Study Overview The research centers on the use of astrocytes derived from human embryonic stem cells (hESCs) as a potential
Incidence, Risk Factors, and Clinico-Radiological Correlations of Early Post-traumatic Seizures: A Prospective Analysis at a Tertiary Care Center in India
Study Overview The investigation into early post-traumatic seizures (EPTS) serves a critical role in understanding the neurological outcomes following traumatic
Bilateral immune-mediated optic neuritis following HPV vaccination in an adolescent: diagnostic challenges and a rare clinical presentation
Case Presentation A 16-year-old female patient presented with sudden onset bilateral vision loss following her first dose of the human