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neuronal activity

Traumatic brain injury
Brain-derived exosomes from aged mice accelerate cognitive decline in repeated mild traumatic brain injury by activating neuronal Tnfrsf25

by myneuronews October 18, 2025

by myneuronews October 18, 2025

Exosome Characteristics Exosomes are small extracellular vesicles that range from 30 to 150 nanometers in …

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Headaches
MEG Analysis of Cortical Activity and Network Topology During the Interictal Period of Migraine Without Aura

by myneuronews October 11, 2025

by myneuronews October 11, 2025

Cortical Activity Patterns The study of cortical activity patterns provides significant insights into the brain’s …

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Functional neurological disorders
Serum biomarkers in epilepsy: More than meets the eye

by myneuronews October 10, 2025

by myneuronews October 10, 2025

Serum Biomarkers Overview Serum biomarkers have emerged as a critical aspect of understanding and diagnosing …

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Traumatic brain injury
Detecting mild traumatic brain injury with MEG scan data: One-vs-K-sample tests

by myneuronews September 11, 2025

by myneuronews September 11, 2025

Study Overview The research explored the effectiveness of magnetoencephalography (MEG) in detecting mild traumatic brain …

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Headaches
Intranasal Empagliflozin Modulates Synaptic Plasticity in Migraine: Insights into Calcium Signaling and Epigenetic Regulation

by myneuronews August 31, 2025

by myneuronews August 31, 2025

Mechanisms of Action Empagliflozin, a sodium-glucose cotransporter 2 (SGLT2) inhibitor, primarily functions by reducing glucose …

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Headaches
State-of-the-art preclinical techniques to study the impact of spreading depolarizations in awake rodents

by myneuronews August 29, 2025

by myneuronews August 29, 2025

Overview of Spreading Depolarizations Spreading depolarizations (SDs) refer to a wave of electrical activity that …

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Functional neurological disorders
Management of Functional Neurological Disorder

by myneuronews August 28, 2025

by myneuronews August 28, 2025

Overview of Functional Neurological Disorder Functional Neurological Disorder (FND) manifests as a group of neurological …

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Functional neurological disorders
Bridging the Mind and Body: Functional Neurologic Symptom Disorder Following Sexual Trauma in an Adolescent Girl

by myneuronews August 18, 2025

by myneuronews August 18, 2025

Case Presentation The case involves a 15-year-old girl who presented with a range of neurological …

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Traumatic brain injury
The Effect of Intracellular Calcium Buffer Bapta on Epileptiform Activity of Hippocampal Neurons

by myneuronews August 14, 2025

by myneuronews August 14, 2025

Study Overview The investigation focuses on the role of intracellular calcium buffering in modulating epileptiform …

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Traumatic brain injury
The Effect of Intracellular Calcium Buffer Bapta on Epileptiform Activity of Hippocampal Neurons

by myneuronews August 14, 2025

by myneuronews August 14, 2025

Study Overview The primary objective of this study was to investigate the role of Bapta, …

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The clinical and cost-effectiveness of sertraline in preventing depression in adults following a traumatic brain injury (STOP-D): study protocol for a multi-centre randomised controlled trial
BACKGROUND: Traumatic brain injury (TBI) is a common presentation in emergency departments worldwide. Approximately 1.4 million adults present with TBI in England and Wales annually. Post-TBI depression (PTD) is a common neuropsychiatric consequence, affecting up to 50% of patients within two years, and is associated with adverse functional outcomes. PTD remains underdiagnosed and undertreated. Sertraline, […]
A sensor-based gait measure for identifying invalid performance in simulated mTBI: an experimental proof of concept
CONCLUSIONS: Findings offer preliminary support for the ability of an automated gait-based measure to capture invalid performance and inform investigations regarding effort. These experimental findings represent a first step in exploring the potential clinical utility of the BKG as a measure of performance validity.
The Relationship of Prior Concussion and Contact Sport Exposure With Cortical Macro and Microstructure
Changes in cortical gray matter are a key feature of neurodegenerative diseases that have been linked with concussion and repetitive head impacts (RHIs). Prior evidence implicates prior concussion and RHI in reduced cortical thickness or volume in temporal and frontal regions, with results largely restricted to older retired contact sport athletes. Fewer studies have investigated […]
Impact of Modified Brain Injury Guideline Incorporating Neurosurgical Consultation on Resource Utilization and Follow-Up Care in Complicated Mild Traumatic Brain Injury
CONCLUSION: Implementation of a resource utilization-focused protocol at our trauma center incorporating neurosurgery consultation for patients with complicated mTBI led to higher rates of direct discharges from the ED and to home without compromising TBI-related follow-up care. Results demonstrate that adoption of a modified BIG protocol that includes neurosurgical collaboration can translate to more efficient […]
Timing of definitive fracture fixation in patients with concomitant traumatic brain injuries - A systematic review of the literature by the IMPACT group
CONCLUSIONS: Early definitive fracture fixation within 24 h should be attempted in polytrauma patients with concomitant mild TBI under specific conditions, which were previously defined by the IMPACT group. Furthermore, current evidence suggests that this approach is both safe and beneficial in a carefully selected patient population. In cases of moderate and severe TBI, decision-making […]