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neuronal activity

Functional neurological disorders
Development and in vitro characterization of humanized antibodies for blocking human TRPM4 channel

by myneuronews June 5, 2025

by myneuronews June 5, 2025

Background on TRPM4 Channel The TRPM4 channel, a member of the transient receptor potential (TRP) …

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Functional neurological disorders
Development and in vitro characterization of humanized antibodies for blocking human TRPM4 channel

by myneuronews June 5, 2025

by myneuronews June 5, 2025

Development of Humanized Antibodies The study focuses on the creation of humanized antibodies targeting the …

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Traumatic brain injury
Pain Management in Mild Traumatic Brain Injury: Central Sensitization as a Multispecialty Challenge

by myneuronews June 4, 2025

by myneuronews June 4, 2025

Understanding Central Sensitization Central sensitization is a crucial phenomenon related to the heightened sensitivity to …

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Functional neurological disorders
Neuron-Inspired Ferroelectric Bioelectronics for Adaptive Biointerfacing

by myneuronews May 30, 2025

by myneuronews May 30, 2025

Overview of Ferroelectric Bioelectronics Ferroelectric bioelectronics represent a fascinating intersection of materials science and biological …

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Functional neurological disorders
A conserved epilepsy-associated gene co-expression module identifies increased metabolic rate as a shared pathomechanism

by myneuronews May 22, 2025

by myneuronews May 22, 2025

Gene Co-Expression Module Analysis The research took a deep dive into how specific genes interact …

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Traumatic brain injury
Mild Traumatic Brain Injury Impairs Fear Extinction and Network Excitability in the Infralimbic Cortex

by myneuronews May 22, 2025

by myneuronews May 22, 2025

Study Overview The study aimed to investigate the effects of mild traumatic brain injury (mTBI) …

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Traumatic brain injury
Neuroimaging Characterization of Acute Traumatic Brain Injury with Focus on Frontline Clinicians: Recommendations from the 2024 National Institute of Neurological Disorders and Stroke Traumatic Brain Injury Classification and Nomenclature Initiative Imaging Working Group

by myneuronews May 20, 2025

by myneuronews May 20, 2025

Neuroimaging Techniques in Traumatic Brain Injury Neuroimaging plays a crucial role in the assessment and …

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Traumatic brain injury
Brain activity dynamics after traumatic brain injury indicate increased state transition energy and preference of lower order states

by myneuronews May 17, 2025

by myneuronews May 17, 2025

Brain Activity Dynamics in TBI Traumatic brain injury (TBI) significantly disrupts normal brain function, leading …

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Traumatic brain injury
Inhibition of TRPM3 channels in the medial prefrontal cortex mitigates OCD symptoms following traumatic brain injury

by myneuronews May 15, 2025

by myneuronews May 15, 2025

TRPM3 Channel Function in the Brain The TRPM3 channel, a member of the transient receptor …

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Functional neurological disorders
Automated seizure detection in epilepsy using a novel dynamic temporal-spatial graph attention network

by myneuronews May 12, 2025

by myneuronews May 12, 2025

Methodology and Model Architecture The study introduces a sophisticated machine learning approach aimed at enhancing …

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Real-world assessment of current migraine prophylaxis in Egypt: a multicenter national study
Study Overview The research conducted aimed to evaluate the existing practices regarding migraine prophylaxis across…
Treatment of Alzheimer’s disease from gut-brain interactions based on theory of “spleen deficiency leading to obstruction of nine orifices”
Understanding Gut-Brain Interactions The relationship between the gut and the brain is increasingly recognized as…
Update on functional vestibular and gait disorders
Current Understanding of Vestibular and Gait Disorders Vestibular and gait disorders have increasingly garnered attention…
Brain creatine concentrations are associated with sex and symptom severity after concussion: a cross-sectional MR-spectroscopy investigation of adolescents with concussion
Study Overview The investigation focused on the relationship between brain creatine concentrations and both sex…
Anti-Inflammatory Potential of Stearidonic Acid Ethanolamide in a Model of Mild Traumatic Brain Injury in Mice
Study Overview This study investigates the effects of stearidonic acid ethanolamide (SDA-EA) on inflammation following…

Relationship between illness perceptions, coping style and post-concussion symptoms after systemic traumatic injury: A comparison of those with and without mild traumatic brain injury
Research has reported variable findings when investigating the relationship between outcome and coping style and illness perceptions after mild traumatic brain injury (mTBI). The present study investigated 138 individuals who had been admitted to hospital after suffering a traumatic systemic injury, with 91 of these individuals also fulfilling criteria for mTBI and 47 comprising a […]
Injury-induced CTE-like pathology emerges in a human multicellular in vitro brain model and reveals mitochondrial and neurovascular regulation
Chronic traumatic encephalopathy (CTE) is a progressive neurodegenerative disease linked to repetitive mild head impacts, but no human-based experimental system exists to study injury-induced CTE-like pathology. Here, we establish a long-lived, human multicellular in vitro brain platform in which controlled mechanical injury induces key cellular features of CTE-like pathology. Injured cultures developed persistent tau phosphorylation, […]
Explosive shock wave exposure leads to age-accelerated motor and sensory decline in C. elegans
CONCLUSIONS: Defined shock wave exposure is sufficient to provoke long-term neuronal functional decline in C. elegans , accompanied by structural deterioration and premature neurodegeneration. This tractable model enables lifelong phenotyping and mechanistic dissection of how an acute shock wave insult progresses to chronic neuronal dysfunction, and provides a scalable platform for identifying molecular and pharmacological […]
Management of the paediatric patient with acute head trauma
Acute head trauma (AHT) leading to traumatic brain injury is an important cause of paediatric morbidity and mortality. Injury severity depends on the mechanism of trauma and age of the child. The vast majority of childhood AHT cases are mild, require no therapy, and leave no long-term sequelae. However, it is important to identify individuals […]
Brain creatine concentrations are associated with sex and symptom severity after concussion: a cross-sectional MR-spectroscopy investigation of adolescents with concussion
CONCLUSION: Post-concussion sex differences in creatine concentrations were detected, as higher creatine levels moderately correlated with patient-reported outcomes. Creatine may reflect altered energy dynamics in the brain. The absence of a non-injured control group limits determination of whether these differences are concussion-specific or reflective of baseline physiology.