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neuronal cell death

Traumatic brain injury
Snapin mediates neuronal PANoptosis after mild traumatic brain injury via H(2)S-dependent S-sulfhydration of CTSD

by myneuronews January 20, 2026

by myneuronews January 20, 2026

Study Overview The research focuses on the role of Snapin, a protein that contributes to …

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Dementia
GASDERMIN D-mediated pyroptosis as a therapeutic target in TAU-dependent frontotemporal dementia mouse model

by myneuronews January 4, 2026

by myneuronews January 4, 2026

Study Overview The research focuses on the role of GASDERMIN D in the context of …

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Traumatic brain injury
Ferroptosis-Mediated Hippocampal Neuronal Loss Post-mTBI: Chromatin Accessibility Profiling and Single-Nucleus Transcriptomics

by myneuronews December 15, 2025

by myneuronews December 15, 2025

Research Context The brain is a complex organ with numerous cellular interactions, and understanding these …

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Traumatic brain injury
Influence of oxidative stress caused by a blast wave in acoustic barotrauma on the auditory analyzer

by myneuronews August 23, 2025

by myneuronews August 23, 2025

Impact of Oxidative Stress Oxidative stress is a condition characterized by an imbalance between the …

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Traumatic brain injury
Advancing next-generation brain organoid platforms for investigating traumatic brain injury from repeated blast exposures

by myneuronews July 3, 2025

by myneuronews July 3, 2025

Study Overview The research investigates the utilization of advanced brain organoid platforms to explore the …

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Traumatic brain injury
Cannabidiol inhibits neuronal endoplasmic reticulum stress and apoptosis in rats with multiple concussions by regulating the PERK-eIF2alpha-ATF4-CHOP pathway

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Neuronal Endoplasmic Reticulum Stress and Apoptosis The endoplasmic reticulum (ER) plays a crucial role in …

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Traumatic brain injury
Single-Cell RNA and Transcriptome Sequencing to Analyze the Role of Lactate Metabolism in Traumatic Brain Injury Astrocytes

by myneuronews May 21, 2025

by myneuronews May 21, 2025

Role of Lactate Metabolism in Astrocytes Lactate metabolism plays a pivotal role in cellular energy …

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Traumatic brain injury
Cellular and molecular mechanisms of pathological tau phosphorylation in traumatic brain injury: implications for chronic traumatic encephalopathy

by myneuronews May 10, 2025

by myneuronews May 10, 2025

Pathological Tau Phosphorylation Mechanisms Tau protein is a key player in maintaining the structural integrity …

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Medical professionals Post traumatic epilepsy Traumatic brain injury
Understanding the Pathophysiology of Post-Traumatic Epilepsy

by Ioannis Mavroudis February 14, 2024

by Ioannis Mavroudis February 14, 2024

Astrocytes, traditionally viewed as mere support cells, play a pivotal role in the development of …

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Refinement and validation of sources of reading self-efficacy scale for college and university students (SOURSES-C) in college students with concussion
CONCLUSION: These findings support the SOURSES-C as a psychometrically sound tool for assessing reading self-efficacy in college students with concussion. With further validation, the scale shows promise as a measure that clinicians and educators can use to identify changes in reading self-efficacy following concussion and to evaluate the effectiveness of targeted interventions.
Paediatric concussion in general practice
BACKGROUND: General practitioners (GPs) have a key role in concussion diagnosis and management. Recent surveys have shown that GPs are competent in diagnosis but lack confidence in appropriate concussion management. Although some patients recover spontaneously, early education is valuable, and provision of evidence-informed, individualised management plans may facilitate recovery within typical recovery windows. OBJECTIVE: The […]
Concussion
No abstract
Supporting return to study and return to work in the patient with persistent post-concussion symptoms: A biopsychosocial approach
BACKGROUND: Concussion, or mild uncomplicated traumatic brain injury (mTBI), is a common condition that can occur in sports, motor vehicle accidents, falls, assaults/violence and occupational settings. While symptom resolution is usually expected within 2-4 weeks, a minority of patients (up to 30%) experience persistent post-concussion symptoms (PPCS) that impact cognitive, physical and emotional functioning. These […]
Multidisciplinary care in concussion management
BACKGROUND: About 30% of people who experience a concussion have longer-lasting symptoms and complex care requirements. The new Australian and New Zealand clinical practice guidelines for the management of concussion, mild traumatic brain injury and persisting concussion symptoms provide guidance for their management, which often requires the involvement of multiple disciplines in a collaborative approach […]