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neuronal cell death

Traumatic brain injury
Snapin mediates neuronal PANoptosis after mild traumatic brain injury via H(2)S-dependent S-sulfhydration of CTSD

by myneuronews January 20, 2026

by myneuronews January 20, 2026

Study Overview The research focuses on the role of Snapin, a protein that contributes to …

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Dementia
GASDERMIN D-mediated pyroptosis as a therapeutic target in TAU-dependent frontotemporal dementia mouse model

by myneuronews January 4, 2026

by myneuronews January 4, 2026

Study Overview The research focuses on the role of GASDERMIN D in the context of …

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Traumatic brain injury
Ferroptosis-Mediated Hippocampal Neuronal Loss Post-mTBI: Chromatin Accessibility Profiling and Single-Nucleus Transcriptomics

by myneuronews December 15, 2025

by myneuronews December 15, 2025

Research Context The brain is a complex organ with numerous cellular interactions, and understanding these …

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Traumatic brain injury
Influence of oxidative stress caused by a blast wave in acoustic barotrauma on the auditory analyzer

by myneuronews August 23, 2025

by myneuronews August 23, 2025

Impact of Oxidative Stress Oxidative stress is a condition characterized by an imbalance between the …

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Traumatic brain injury
Advancing next-generation brain organoid platforms for investigating traumatic brain injury from repeated blast exposures

by myneuronews July 3, 2025

by myneuronews July 3, 2025

Study Overview The research investigates the utilization of advanced brain organoid platforms to explore the …

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Traumatic brain injury
Cannabidiol inhibits neuronal endoplasmic reticulum stress and apoptosis in rats with multiple concussions by regulating the PERK-eIF2alpha-ATF4-CHOP pathway

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Neuronal Endoplasmic Reticulum Stress and Apoptosis The endoplasmic reticulum (ER) plays a crucial role in …

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Traumatic brain injury
Single-Cell RNA and Transcriptome Sequencing to Analyze the Role of Lactate Metabolism in Traumatic Brain Injury Astrocytes

by myneuronews May 21, 2025

by myneuronews May 21, 2025

Role of Lactate Metabolism in Astrocytes Lactate metabolism plays a pivotal role in cellular energy …

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Traumatic brain injury
Cellular and molecular mechanisms of pathological tau phosphorylation in traumatic brain injury: implications for chronic traumatic encephalopathy

by myneuronews May 10, 2025

by myneuronews May 10, 2025

Pathological Tau Phosphorylation Mechanisms Tau protein is a key player in maintaining the structural integrity …

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Medical professionals Post traumatic epilepsy Traumatic brain injury
Understanding the Pathophysiology of Post-Traumatic Epilepsy

by Ioannis Mavroudis February 14, 2024

by Ioannis Mavroudis February 14, 2024

Astrocytes, traditionally viewed as mere support cells, play a pivotal role in the development of …

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Combined Uyghur medicine, acupuncture, and rehabilitation for traumatic oculomotor nerve palsy: A case report
CONCLUSION: This case demonstrates that an integrated treatment approach combining Uyghur medicine, rehabilitation training, and acupuncture yields significant therapeutic efficacy in improving ocular motor dysfunction secondary to complex traumatic brain injury.
Paediatric Sport-Related Concussion and Hospitalisation in Australia
No abstract
Extracellular Vesicle-Derived microRNAs as Fluid Biomarkers in Neurodegenerative Diseases: A Systematic Review
Given the absence of curative treatments for neurodegenerative diseases, early detection and therapeutic intervention are critical to slowing disease progression. Extracellular vesicles (EVs) have emerged as promising biomarkers for neurodegeneration, owing to their accessibility in bodily fluids and dynamic molecular cargo, including microRNAs (miRNAs). The last decade has seen accumulating evidence for miRNA dysregulation in […]
P75NTR blockading inhibits Trem2+ M1 phenotype microglia activation and myelin damage following mild traumatic brain injury
The pathological basis underlying mild traumatic brain injury (mTBI)-induced long-term cognitive impairment is not fully understood. It is supposed that mTBI induces residential microglia activation rather than peripheral leukocyte infiltration to promote neuroinflammation, thus triggering myelin damage as well as cognitive impairment. The transformation of microglia towards a pro-inflammatory (M1 type) or anti-inflammatory (M2 type) […]
Biofluid-based predictors of post-concussion symptoms: a narrative review of mild traumatic brain injury biomarkers
Mild traumatic brain injury can disrupt brain function and is associated with high morbidity and healthcare utilization. While many individuals recover from mild traumatic brain injury, a significant proportion experience long-term sequelae, collectively known as post-concussion syndrome. Symptoms of post-concussion syndrome include headache, dizziness, insomnia, cognitive processing difficulties and mental health disturbances. The disease burden […]