Tag:

neuronal cell death

Dementia
GASDERMIN D-mediated pyroptosis as a therapeutic target in TAU-dependent frontotemporal dementia mouse model

by myneuronews January 4, 2026

by myneuronews January 4, 2026

Study Overview The research focuses on the role of GASDERMIN D in the context of …

Read more

0 Facebook Twitter Pinterest Email
Traumatic brain injury
Ferroptosis-Mediated Hippocampal Neuronal Loss Post-mTBI: Chromatin Accessibility Profiling and Single-Nucleus Transcriptomics

by myneuronews December 15, 2025

by myneuronews December 15, 2025

Research Context The brain is a complex organ with numerous cellular interactions, and understanding these …

Read more

0 Facebook Twitter Pinterest Email
Traumatic brain injury
Influence of oxidative stress caused by a blast wave in acoustic barotrauma on the auditory analyzer

by myneuronews August 23, 2025

by myneuronews August 23, 2025

Impact of Oxidative Stress Oxidative stress is a condition characterized by an imbalance between the …

Read more

0 Facebook Twitter Pinterest Email
Traumatic brain injury
Advancing next-generation brain organoid platforms for investigating traumatic brain injury from repeated blast exposures

by myneuronews July 3, 2025

by myneuronews July 3, 2025

Study Overview The research investigates the utilization of advanced brain organoid platforms to explore the …

Read more

0 Facebook Twitter Pinterest Email
Traumatic brain injury
Cannabidiol inhibits neuronal endoplasmic reticulum stress and apoptosis in rats with multiple concussions by regulating the PERK-eIF2alpha-ATF4-CHOP pathway

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Neuronal Endoplasmic Reticulum Stress and Apoptosis The endoplasmic reticulum (ER) plays a crucial role in …

Read more

0 Facebook Twitter Pinterest Email
Traumatic brain injury
Single-Cell RNA and Transcriptome Sequencing to Analyze the Role of Lactate Metabolism in Traumatic Brain Injury Astrocytes

by myneuronews May 21, 2025

by myneuronews May 21, 2025

Role of Lactate Metabolism in Astrocytes Lactate metabolism plays a pivotal role in cellular energy …

Read more

0 Facebook Twitter Pinterest Email
Traumatic brain injury
Cellular and molecular mechanisms of pathological tau phosphorylation in traumatic brain injury: implications for chronic traumatic encephalopathy

by myneuronews May 10, 2025

by myneuronews May 10, 2025

Pathological Tau Phosphorylation Mechanisms Tau protein is a key player in maintaining the structural integrity …

Read more

0 Facebook Twitter Pinterest Email
Medical professionals Post traumatic epilepsy Traumatic brain injury
Understanding the Pathophysiology of Post-Traumatic Epilepsy

by Ioannis Mavroudis February 14, 2024

by Ioannis Mavroudis February 14, 2024

Astrocytes, traditionally viewed as mere support cells, play a pivotal role in the development of …

Read more

1 Facebook Twitter Pinterest Email

Peripheral Nerve Stimulation Is Effective in the Management of Trigeminal Pain: A Systematic Review and meta-analysis
Study Overview The systematic review and meta-analysis addressed the effectiveness of peripheral nerve stimulation (PNS)…
Evaluation of Suspected Dementia
Understanding Dementia Evaluation Dementia evaluation is a complex process designed to identify cognitive decline that…
Study of ubiquitin C-terminal hydrolase-L1, glial fibrillary acidic protein, and interleukin-6 levels in an experimental head trauma model in rabbits
Study Overview This research investigates the roles of specific biomarkers—ubiquitin C-terminal hydrolase-L1 (UCH-L1), glial fibrillary…
Correlation of Optic Nerve Sheath Diameter With Severity and Outcome in Head Injury: Ultrasonographic and CT Evaluation
Study Overview The research focused on evaluating the relationship between the diameter of the optic…
Admission blood glucose and neutrophil-to-lymphocyte ratio for differentiating CT-positive from CT-negative mild traumatic brain injury
Study Overview This research investigates the potential of admission blood glucose levels and the neutrophil-to-lymphocyte…

Establishing Normative Data for Single- and Dual-Task Tandem Gait in Healthy Interuniversity Male and Female Athletes
CONCLUSIONS: Healthy male athletes performed single- and dual-task tandem gait faster than female athletes. In addition, most athletes performed below the "normal" ranges according to SCOAT6 criteria, suggesting that normative performance values for tandem gait may need revisiting to enhance clinical interpretation.
Correction: Retraining dorsal visual pathways improves cognitive skills and executive control networks following mild traumatic brain injury
[This corrects the article DOI: 10.3389/fnhum.2025.1698605.].
Study of ubiquitin C-terminal hydrolase-L1, glial fibrillary acidic protein, and interleukin-6 levels in an experimental head trauma model in rabbits
CONCLUSION: Serum UCH-L1 differentiated moderate and severe trauma from controls in a rabbit model, whereas CSF GFAP and IL-6 levels reflected severe injury. Validation in larger preclinical and clinical studies is warranted.
Correlation of Optic Nerve Sheath Diameter With Severity and Outcome in Head Injury: Ultrasonographic and CT Evaluation
Objective This study aimed to determine the extent to which ultrasonographic and computed tomographic (CT) measurements of the optic nerve sheath diameter (ONSD) correlate with the prognosis and severity of traumatic brain injury (TBI). Methodology A prospective cohort study was conducted among 200 adult patients admitted to a Level 1 trauma center over one year. […]
COVID-19 Vaccination Among Persons with Complicated Mild to Severe Traumatic Brain Injury (TBI): A TBI Model Systems Study
CONCLUSION: Demographic disparities in vaccination uptake exist among individuals with TBI, but vaccination status was not independently linked to mental health, participation, or quality of life outcomes. These findings underscore the need for targeted outreach to address vaccination gaps and promote health equity in this vulnerable population.