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neuronal cell death

Traumatic brain injury
Snapin mediates neuronal PANoptosis after mild traumatic brain injury via H(2)S-dependent S-sulfhydration of CTSD

by myneuronews January 20, 2026

by myneuronews January 20, 2026

Study Overview The research focuses on the role of Snapin, a protein that contributes to …

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Dementia
GASDERMIN D-mediated pyroptosis as a therapeutic target in TAU-dependent frontotemporal dementia mouse model

by myneuronews January 4, 2026

by myneuronews January 4, 2026

Study Overview The research focuses on the role of GASDERMIN D in the context of …

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Traumatic brain injury
Ferroptosis-Mediated Hippocampal Neuronal Loss Post-mTBI: Chromatin Accessibility Profiling and Single-Nucleus Transcriptomics

by myneuronews December 15, 2025

by myneuronews December 15, 2025

Research Context The brain is a complex organ with numerous cellular interactions, and understanding these …

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Traumatic brain injury
Influence of oxidative stress caused by a blast wave in acoustic barotrauma on the auditory analyzer

by myneuronews August 23, 2025

by myneuronews August 23, 2025

Impact of Oxidative Stress Oxidative stress is a condition characterized by an imbalance between the …

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Traumatic brain injury
Advancing next-generation brain organoid platforms for investigating traumatic brain injury from repeated blast exposures

by myneuronews July 3, 2025

by myneuronews July 3, 2025

Study Overview The research investigates the utilization of advanced brain organoid platforms to explore the …

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Traumatic brain injury
Cannabidiol inhibits neuronal endoplasmic reticulum stress and apoptosis in rats with multiple concussions by regulating the PERK-eIF2alpha-ATF4-CHOP pathway

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Neuronal Endoplasmic Reticulum Stress and Apoptosis The endoplasmic reticulum (ER) plays a crucial role in …

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Traumatic brain injury
Single-Cell RNA and Transcriptome Sequencing to Analyze the Role of Lactate Metabolism in Traumatic Brain Injury Astrocytes

by myneuronews May 21, 2025

by myneuronews May 21, 2025

Role of Lactate Metabolism in Astrocytes Lactate metabolism plays a pivotal role in cellular energy …

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Traumatic brain injury
Cellular and molecular mechanisms of pathological tau phosphorylation in traumatic brain injury: implications for chronic traumatic encephalopathy

by myneuronews May 10, 2025

by myneuronews May 10, 2025

Pathological Tau Phosphorylation Mechanisms Tau protein is a key player in maintaining the structural integrity …

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Medical professionals Post traumatic epilepsy Traumatic brain injury
Understanding the Pathophysiology of Post-Traumatic Epilepsy

by Ioannis Mavroudis February 14, 2024

by Ioannis Mavroudis February 14, 2024

Astrocytes, traditionally viewed as mere support cells, play a pivotal role in the development of …

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Supernatural-Functiolistic-Expialidocious: A Comparative Study Between Functional Neurological Symptom Disorder/Conversion Disorder and Other Psychiatric Conditions
Study Overview The research undertaken explores the complex interplay between Functional Neurological Symptom Disorder (FND),…
Diagnostic labels in functional disorders
Understanding Functional Disorders Functional disorders encompass a range of conditions where patients experience symptoms that…
Intraoperative Electroneurography (ENoG) of Facial Nerve Conduction during Mandibular Distraction Osteogenesis for Robin Sequence
Study Overview The study investigates the efficacy and safety of intraoperative electroneurography (ENoG) as a…
Implementation of Virtual Reality for Postoperative Recovery in an Adolescent Idiopathic Scoliosis Population: a Prospective Pilot Study
Study Overview This study investigates the implementation of virtual reality (VR) as a tool to…
The Impact of Hearing Loss on Annual Incident Age-Associated Dementia Cases and Quality of Life in the US
Impact of Hearing Loss on Dementia Incidence Hearing loss has emerged as a significant risk…

Defining significant acute traumatic intracranial injuries in adult patients with traumatic brain injury: a narrative review
CONCLUSION: To date, there is no contemporary consensus definition of a significant acute traumatic intracranial lesion in patients presenting with TBI. Several factors appear essential for defining a significant lesion, including comorbidities, clinical presentation, CT scan injury characteristics and biomarkers.
Combined transcranial electrical stimulation (tES) and cognitive training (CT) for cognitive impairment: Evidence from clinical applications and basic research
Cognitive impairment is a serious pathological feature of neuropsychiatric disorders, making the exploration of effective treatments urgent. Recent research shows that combined transcranial electrical stimulation (tES) and cognitive training (CT) can reduce cognitive deficits. This review summarizes studies on neurological disorders that use both clinical patients and rodent models to highlight the underlying neural mechanisms. […]
Outcomes of soccer-related concussion: A systematic review
CONCLUSION: The literature on outcomes following SoRC remains mixed. The limited and inconsistent evidence across symptoms, recovery, and neurocognitive domains highlights the need for standardised measures and more longitudinal studies to guide clinical management and the development of RTP protocols. PROSPERO Registration Number CRD42024519427.
Relationship Between Sport Specialization and Short-Term Health-Related Quality of Life in Youth Athletes After Injury
CONCLUSION: Higher level of sport specialization is not associated with worse HRQoL approximately 1 month after sport-related injury. Female athletes have worse short-term HRQoL after an injury irrespective of sport specialization level. While sex differences were statistically significant, the magnitude of differences was small.
Behavioral treatment of insomnia in active-duty service members with traumatic brain injury: study protocol for a randomized clinical trial
BACKGROUND: Traumatic brain injury (TBI) in the U.S. military can result in lasting health issues, with insomnia being a common symptom that worsens recovery, cognitive function, and performance, especially when combined with common co-occurring conditions like chronic pain, post-traumatic stress disorder (PTSD), and depression. Insomnia may be an important intervention target for managing post-concussive symptoms […]