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neuronal cell death

Traumatic brain injury
Advancing next-generation brain organoid platforms for investigating traumatic brain injury from repeated blast exposures

by myneuronews July 3, 2025

by myneuronews July 3, 2025

Study Overview The research investigates the utilization of advanced brain organoid platforms to explore the …

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Traumatic brain injury
Cannabidiol inhibits neuronal endoplasmic reticulum stress and apoptosis in rats with multiple concussions by regulating the PERK-eIF2alpha-ATF4-CHOP pathway

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Neuronal Endoplasmic Reticulum Stress and Apoptosis The endoplasmic reticulum (ER) plays a crucial role in …

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Functional neurological disorders
Loss of CD98HC phosphorylation by ATM impairs antiporter trafficking and drives glutamate toxicity in Ataxia telangiectasia

by myneuronews June 2, 2025

by myneuronews June 2, 2025

Loss of CD98HC Phosphorylation and Its Consequences Recent research has highlighted the significant role of …

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Traumatic brain injury
Single-Cell RNA and Transcriptome Sequencing to Analyze the Role of Lactate Metabolism in Traumatic Brain Injury Astrocytes

by myneuronews May 21, 2025

by myneuronews May 21, 2025

Role of Lactate Metabolism in Astrocytes Lactate metabolism plays a pivotal role in cellular energy …

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Traumatic brain injury
Cellular and molecular mechanisms of pathological tau phosphorylation in traumatic brain injury: implications for chronic traumatic encephalopathy

by myneuronews May 10, 2025

by myneuronews May 10, 2025

Pathological Tau Phosphorylation Mechanisms Tau protein is a key player in maintaining the structural integrity …

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Medical professionals Post traumatic epilepsy Traumatic brain injury
Understanding the Pathophysiology of Post-Traumatic Epilepsy

by Ioannis Mavroudis February 14, 2024

by Ioannis Mavroudis February 14, 2024

Astrocytes, traditionally viewed as mere support cells, play a pivotal role in the development of …

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A systematic review of cheerleading injuries: epidemiological characteristics, biomechanical mechanisms, and prevention strategies
CONCLUSION: Cheerleading injury prevention requires a multidimensional strategy: Implement biomechanical interventions (closed-chain eccentric training and movement technique optimization) to enhance muscle endurance and action control precision; Promote rule optimization and coach certification, establishing standardized difficulty criteria for each level and a risk factor-based assessment and prevention system; Develop pediatric protection standards and professional training systems, […]
Microglial depletion and repopulation differentially modulate sleep and inflammation in a mouse model of traumatic brain injury
Traumatic brain injury (TBI) causes persistent sleep disturbances, leading to long-term neurological consequences and reduced quality of life. We hypothesized that microglial depletion via PLX5622 (PLX), a colony-stimulating factor 1 receptor (CSFR1R) inhibitor, would exacerbate sleep disturbances and alter inflammatory profiles after TBI, and that microglial repopulation would ameliorate these effects. Male mice received PLX […]
Gender Differences in Seeking and Receiving Healthcare After Mild Traumatic Brain Injury
CONCLUSIONS: Women reported worse symptoms but did not receive more specialty clinical care. Women are more likely to report having under-treated mental health problems. Future studies are needed to confirm whether women have a greater mismatch between their need for and receipt of rehabilitation services and explore mechanisms contributing to this gap.
Waiting time for specialized interdisciplinary rehabilitation associated with persistent symptoms of mild traumatic brain injury: an observational cohort study
CONCLUSION: This study reveals the negative effects of delayed access to specialized rehabilitation services for patients with mTBI and calls for necessary policy changes.
Spatial navigation skills in older adults with and without cognitive impairment
CONCLUSION: This study provides valuable insights into navigation impairments associated with cognitive decline in aging populations, paving the way for targeted interventions to preserve navigation skills in affected individuals.

neuronal cell death

Advancing next-generation brain organoid platforms for investigating traumatic brain injury from repeated blast exposures

Cannabidiol inhibits neuronal endoplasmic reticulum stress and apoptosis in rats with multiple concussions by regulating the PERK-eIF2alpha-ATF4-CHOP pathway

Loss of CD98HC phosphorylation by ATM impairs antiporter trafficking and drives glutamate toxicity in Ataxia telangiectasia

Single-Cell RNA and Transcriptome Sequencing to Analyze the Role of Lactate Metabolism in Traumatic Brain Injury Astrocytes

Cellular and molecular mechanisms of pathological tau phosphorylation in traumatic brain injury: implications for chronic traumatic encephalopathy

Understanding the Pathophysiology of Post-Traumatic Epilepsy