Tag:

neuronal cell death

Dementia
GASDERMIN D-mediated pyroptosis as a therapeutic target in TAU-dependent frontotemporal dementia mouse model

by myneuronews January 4, 2026

by myneuronews January 4, 2026

Study Overview The research focuses on the role of GASDERMIN D in the context of …

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Traumatic brain injury
Ferroptosis-Mediated Hippocampal Neuronal Loss Post-mTBI: Chromatin Accessibility Profiling and Single-Nucleus Transcriptomics

by myneuronews December 15, 2025

by myneuronews December 15, 2025

Research Context The brain is a complex organ with numerous cellular interactions, and understanding these …

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Traumatic brain injury
Influence of oxidative stress caused by a blast wave in acoustic barotrauma on the auditory analyzer

by myneuronews August 23, 2025

by myneuronews August 23, 2025

Impact of Oxidative Stress Oxidative stress is a condition characterized by an imbalance between the …

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Traumatic brain injury
Advancing next-generation brain organoid platforms for investigating traumatic brain injury from repeated blast exposures

by myneuronews July 3, 2025

by myneuronews July 3, 2025

Study Overview The research investigates the utilization of advanced brain organoid platforms to explore the …

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Traumatic brain injury
Cannabidiol inhibits neuronal endoplasmic reticulum stress and apoptosis in rats with multiple concussions by regulating the PERK-eIF2alpha-ATF4-CHOP pathway

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Neuronal Endoplasmic Reticulum Stress and Apoptosis The endoplasmic reticulum (ER) plays a crucial role in …

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Functional neurological disorders
Loss of CD98HC phosphorylation by ATM impairs antiporter trafficking and drives glutamate toxicity in Ataxia telangiectasia

by myneuronews June 2, 2025

by myneuronews June 2, 2025

Loss of CD98HC Phosphorylation and Its Consequences Recent research has highlighted the significant role of …

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Traumatic brain injury
Single-Cell RNA and Transcriptome Sequencing to Analyze the Role of Lactate Metabolism in Traumatic Brain Injury Astrocytes

by myneuronews May 21, 2025

by myneuronews May 21, 2025

Role of Lactate Metabolism in Astrocytes Lactate metabolism plays a pivotal role in cellular energy …

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Traumatic brain injury
Cellular and molecular mechanisms of pathological tau phosphorylation in traumatic brain injury: implications for chronic traumatic encephalopathy

by myneuronews May 10, 2025

by myneuronews May 10, 2025

Pathological Tau Phosphorylation Mechanisms Tau protein is a key player in maintaining the structural integrity …

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Medical professionals Post traumatic epilepsy Traumatic brain injury
Understanding the Pathophysiology of Post-Traumatic Epilepsy

by Ioannis Mavroudis February 14, 2024

by Ioannis Mavroudis February 14, 2024

Astrocytes, traditionally viewed as mere support cells, play a pivotal role in the development of …

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Imported Familial Pulmonary and Cerebral Paragonimiasis in Korea: Cases and Literature Review from a Clinical Grand Round Conference
Study Overview The investigation into familial pulmonary and cerebral paragonimiasis in Korea highlights the challenges…
GASDERMIN D-mediated pyroptosis as a therapeutic target in TAU-dependent frontotemporal dementia mouse model
Study Overview The research focuses on the role of GASDERMIN D in the context of…
Patient-reported outcomes and acceptability of suggestion and hypnosis-based therapy for functional neurological disorder within an NHS service
Patient-Reported Outcomes In examining the results derived from patient-reported outcomes, it is essential to highlight…
Language biomarker screening using AI: a transdiagnostic approach to brain
Language Biomarkers in AI Research Language biomarkers are pivotal in utilizing artificial intelligence for assessing…
Morning sleep inertia and its associated factors: Findings from a nationwide study
Understanding Sleep Inertia Sleep inertia refers to the temporary state of cognitive and physical impairment…

The Clinical Utility of a Novel Multimodal Assessment Battery for Acute Sport-Related Concussion
CONCLUSIONS: Symptom exacerbation during submaximal cardiovascular exercise and postural sway demonstrated clinical utility in detecting impairment within 7 days of a sport-related concussion, whereas event-related potentials and heart rate change during sustained handgrip did not.
Associations of Symptomatic Head Trauma/Concussion Diagnosis with Sleep-Related Outcomes in Children
IntroductionUsing National Health Interview Survey (NHIS) data from 2020 to 2022, we examined associations between a history of symptomatic head trauma/concussion diagnosis with sleep-related outcomes.MethodsGuardians of children aged 2-17 years answered survey questions indicating whether US children had prior symptomatic head trauma and/or a concussion diagnosis. Associations with symptomatic head trauma/concussion diagnosis and sleep outcomes […]
Synthetic Cannabinoid Use and Sports-Related Concussion Risk Among US Adolescents: Implications for School Health Screening and Prevention
CONCLUSIONS: SC use is associated with elevated sports-related concussion risk among adolescents.
Effectiveness of a Customized Rehabilitation Program for Adults With Post-Concussion Syndrome-A Randomized Controlled Crossover Trial
CONCLUSIONS: A shift away from symptom-based management to subgroup-informed customized rehabilitation may be key to advancing patient care and improving clinical outcomes for this population.
Visualizing and Quantifying Impact with Mechanochromic Sensing Paints Based on Self-Assembled Polydiacetylene-Silk Core-Shell Vesicles
Rapid detection and quantification of mechanical impact on surfaces is relevant for many fields, as it enables monitoring of material stresses and integrity or to assess the physiological effects of force on humans for concussions, gait, or blast dosimetry, among others. Accurate and quantitative detection of impact force, especially at high values (100-770 N), is […]