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neuronal cell death

Traumatic brain injury
Single-Cell RNA and Transcriptome Sequencing to Analyze the Role of Lactate Metabolism in Traumatic Brain Injury Astrocytes

by myneuronews May 21, 2025

by myneuronews May 21, 2025

Role of Lactate Metabolism in Astrocytes Lactate metabolism plays a pivotal role in cellular energy …

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Traumatic brain injury
Cellular and molecular mechanisms of pathological tau phosphorylation in traumatic brain injury: implications for chronic traumatic encephalopathy

by myneuronews May 10, 2025

by myneuronews May 10, 2025

Pathological Tau Phosphorylation Mechanisms Tau protein is a key player in maintaining the structural integrity …

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Medical professionals Post traumatic epilepsy Traumatic brain injury
Understanding the Pathophysiology of Post-Traumatic Epilepsy

by Ioannis Mavroudis February 14, 2024

by Ioannis Mavroudis February 14, 2024

Astrocytes, traditionally viewed as mere support cells, play a pivotal role in the development of …

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The role of microglia in multiple sclerosis: implications for treatment with Bruton’s tyrosine kinase inhibitors
Microglia Function in Multiple Sclerosis Microglia, the primary immune cells of the central nervous system…
Impaired physical fitness in pediatric inflammatory bowel disease
Impaired Fitness in Pediatric Patients Pediatric patients with inflammatory bowel disease (IBD), such as Crohn’s…
Research status and future perspectives of IL-27 in the treatment of stroke (Review)
Current Understanding of IL-27 in Stroke Interleukin-27 (IL-27) is a cytokine that belongs to the…
Human Herpesvirus-6 Infectious Meningitis With Lymphadenitis in an Immunocompetent Adult
Study Overview This research explored a case involving Human Herpesvirus-6 (HHV-6) leading to infectious meningitis…
circ_0005654 as a Sponge of the miR-588 Dual Pathway to Promote α-Synuclein Expression
Study Overview The investigation centers around the long non-coding RNA circ_0005654 and its role as…

Unsophisticated AI coaching does not improve performance on symptom and performance validity tests in a Romanian sample of experimental feigners
The present study aimed to investigate the ability of symptom and performance validity indicators to detect experimental feigning with symptom-coaching vs. AI assistance. Fifty-nine undergraduates and community members (45 females, M(Age)=22.6, SD(Age)=2.1; M(Education)=14.5, SD(Education)=1.4) were randomized into three experimental groups: controls (n = 20), symptom-coached feigners (n = 20), and AI-coached feigners (n = 19). […]
Factors affecting mortality risk in pediatric head injuries in Africa: a meta-analysis
CONCLUSION: Our study emphasizes RTA and seizures at presentation as key risk factors for mortality. We recommend early preventive measures, such as infrastructure improvements, to enhance road safety and reduce mortality.
Nonsteroid Anti-Inflammatory Drug Use in Female Elite Ice Hockey Players With and Without Previous Concussions and Musculoskeletal Injuries
Ice hockey is a high-intensity sport with high rates of concussions and musculoskeletal injuries. To manage pain, players may (over) use nonsteroid anti-inflammatory drugs (NSAIDs) which can have adverse health effects. In 2022, the Swedish Women's Elite League (SDHL) became the first women's league to introduce body checking, potentially increasing injury risks and NSAID use. […]
Single-nucleus and spatial signatures of the brainstem in normal brain and mild traumatic brain injury in male mice
The mammalian brainstem is particularly vulnerable to mild traumatic brain injury (mTBI), which is associated with prolonged autonomic dysfunction and coma. The spatial cellular connections within the brainstem or the mechanisms underlying its response to injury have been underestimated. Here, we performed single-nucleus RNA sequencing with spatial transcriptome sequencing in both normal and mTBI brainstems […]
Post-Concussion Changes in the Functional Brain Connectome Relative to Pre-Injury Baseline: A Prospective Observational Study
There is growing concern about the long-term health consequences of concussion, stemming from its high incidence and evidence of post-injury sequelae. This has raised critical questions about clinical assessments of concussion recovery, and whether brain function has fully recovered at medical clearance. The major knowledge gap is only partly addressed by conventional cross-sectional neuroimaging studies, […]

neuronal cell death

Single-Cell RNA and Transcriptome Sequencing to Analyze the Role of Lactate Metabolism in Traumatic Brain Injury Astrocytes

Cellular and molecular mechanisms of pathological tau phosphorylation in traumatic brain injury: implications for chronic traumatic encephalopathy

Understanding the Pathophysiology of Post-Traumatic Epilepsy