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neuronal cell death

Traumatic brain injury
Snapin mediates neuronal PANoptosis after mild traumatic brain injury via H(2)S-dependent S-sulfhydration of CTSD

by myneuronews January 20, 2026

by myneuronews January 20, 2026

Study Overview The research focuses on the role of Snapin, a protein that contributes to …

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Dementia
GASDERMIN D-mediated pyroptosis as a therapeutic target in TAU-dependent frontotemporal dementia mouse model

by myneuronews January 4, 2026

by myneuronews January 4, 2026

Study Overview The research focuses on the role of GASDERMIN D in the context of …

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Traumatic brain injury
Ferroptosis-Mediated Hippocampal Neuronal Loss Post-mTBI: Chromatin Accessibility Profiling and Single-Nucleus Transcriptomics

by myneuronews December 15, 2025

by myneuronews December 15, 2025

Research Context The brain is a complex organ with numerous cellular interactions, and understanding these …

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Traumatic brain injury
Influence of oxidative stress caused by a blast wave in acoustic barotrauma on the auditory analyzer

by myneuronews August 23, 2025

by myneuronews August 23, 2025

Impact of Oxidative Stress Oxidative stress is a condition characterized by an imbalance between the …

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Traumatic brain injury
Advancing next-generation brain organoid platforms for investigating traumatic brain injury from repeated blast exposures

by myneuronews July 3, 2025

by myneuronews July 3, 2025

Study Overview The research investigates the utilization of advanced brain organoid platforms to explore the …

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Traumatic brain injury
Cannabidiol inhibits neuronal endoplasmic reticulum stress and apoptosis in rats with multiple concussions by regulating the PERK-eIF2alpha-ATF4-CHOP pathway

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Neuronal Endoplasmic Reticulum Stress and Apoptosis The endoplasmic reticulum (ER) plays a crucial role in …

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Traumatic brain injury
Single-Cell RNA and Transcriptome Sequencing to Analyze the Role of Lactate Metabolism in Traumatic Brain Injury Astrocytes

by myneuronews May 21, 2025

by myneuronews May 21, 2025

Role of Lactate Metabolism in Astrocytes Lactate metabolism plays a pivotal role in cellular energy …

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Traumatic brain injury
Cellular and molecular mechanisms of pathological tau phosphorylation in traumatic brain injury: implications for chronic traumatic encephalopathy

by myneuronews May 10, 2025

by myneuronews May 10, 2025

Pathological Tau Phosphorylation Mechanisms Tau protein is a key player in maintaining the structural integrity …

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Medical professionals Post traumatic epilepsy Traumatic brain injury
Understanding the Pathophysiology of Post-Traumatic Epilepsy

by Ioannis Mavroudis February 14, 2024

by Ioannis Mavroudis February 14, 2024

Astrocytes, traditionally viewed as mere support cells, play a pivotal role in the development of …

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Blood Glucose as a Prognostic Predictor of Traumatic Brain Injury in Patients That Underwent Surgical Intervention
CONCLUSION: Elevated initial blood glucose levels were associated with poorer outcomes in patients with TBI, especially in those with moderate TBI. Further research, including larger multicenter studies, is needed to validate our findings and explore optimal glucose management strategies.
Lower limb injuries and concussions dominate in collegiate women's ice hockey: a systematic review and meta-analysis
CONCLUSION: The overall injury incidence in collegiate-level women's ice hockey is considerable, with lower limb injuries being the most common injury location and concussions the most frequent injury type. This review establishes a baseline for injury patterns in women's collegiate ice hockey prior to the potential legalisation of body checking in all levels of women's […]
Loss of CAMKK2 and iron-transport proteins-transferrin and its receptor-in the Alzheimer's disease hippocampus: link to tau pathology
INTRODUCTION: Calcium and iron are essential bioelements regulating neuronal function and survival. Dysregulation of calcium signaling and iron homeostasis is implicated in Alzheimer's disease (AD), contributing to oxidative stress, synaptic dysfunction, and neurodegeneration. Previously, using in vitro cell-based models and transgenic mice, we demonstrated that CAMKK2, a calcium/calmodulin-dependent protein kinase, regulates iron transport via transferrin […]
The Effect of Aerobic Exercise on Post-concussion Recovery in Athletes: A Narrative Review
Traumatic brain injuries (TBIs), in particular sports-related concussions (SRCs), are a significant health concern for young athletes in the United States. Historically, treatment has consisted of prolonged physical and cognitive rest, requiring athletes to abstain from activity until symptoms resolve and physician clearance is obtained. However, emerging evidence suggests that the early introduction of light […]
Cortical spreading depression and multi-territorial cortical infarction following traumatic subdural hematoma: A case report and literature review
CONCLUSION: This case highlights the potential contribution of CSD, inferred from characteristic imaging findings, and spreading ischemia to delayed, diffuse hemispheric infarction in the setting of traumatic SDH, emphasizing its pathophysiological mechanisms, diagnostic challenges, and therapeutic implications.