Tag:

neuronal damage

Traumatic brain injury
Brain-derived exosomes from aged mice accelerate cognitive decline in repeated mild traumatic brain injury by activating neuronal Tnfrsf25

by myneuronews October 18, 2025

by myneuronews October 18, 2025

Exosome Characteristics Exosomes are small extracellular vesicles that range from 30 to 150 nanometers in …

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Functional neurological disorders
Serum biomarkers in epilepsy: More than meets the eye

by myneuronews October 10, 2025

by myneuronews October 10, 2025

Serum Biomarkers Overview Recent advancements in the field of epilepsy research have highlighted the potential …

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Traumatic brain injury
Changes in peripheral blood and cognitive performance after nonconcussive head impacts in elite female soccer players

by myneuronews October 7, 2025

by myneuronews October 7, 2025

Study Overview The research investigates the effects of nonconcussive head impacts on both the peripheral …

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Traumatic brain injury
IL6 in Combination with Either NfL, NTproBNP, or GFAP to Safely Discharge Children with Mild Traumatic Brain Injury

by myneuronews October 7, 2025

by myneuronews October 7, 2025

Background and Rationale The investigation into the role of interleukin-6 (IL-6) in conjunction with biomarkers …

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Traumatic brain injury
Author Correction: Aldehydic load as an objective imaging biomarker of mild traumatic brain injury

by myneuronews October 6, 2025

by myneuronews October 6, 2025

Aldehydic Load as Biomarker The study of aldehydic load has garnered attention as a potential …

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Dementia
Differences in inflammatory markers, mitochondrial function, and synaptic proteins in male and female Alzheimer’s disease post mortem brains

by myneuronews October 1, 2025

by myneuronews October 1, 2025

Inflammatory Markers Comparison Research into Alzheimer’s disease has increasingly highlighted the significance of inflammation in …

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Traumatic brain injury
Blocking axon-glial mechanotransduction to prevent concussive brain injury

by myneuronews September 30, 2025

by myneuronews September 30, 2025

Study Overview The research focuses on preventing concussive brain injuries through the inhibition of mechanotransduction …

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Dementia
Albuminuria is associated with increased risk of dementia, independent of eGFR: The SCREAM project

by myneuronews September 23, 2025

by myneuronews September 23, 2025

Association Between Albuminuria and Dementia Risk Recent investigations have illuminated the relationship between albuminuria, a …

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Traumatic brain injury
Neurogranin as a Synaptic Biomarker in Mild Traumatic Brain Injury: A Systematic Review of Diagnostic and Pathophysiological Evidence

by myneuronews September 22, 2025

by myneuronews September 22, 2025

Neurogranin as a Biomarker Neurogranin is a neuronal protein that has garnered attention as a …

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Traumatic brain injury
CD300f enables microglial damage sensing, efferocytosis, and apoptotic cell metabolization after brain injury

by myneuronews September 11, 2025

by myneuronews September 11, 2025

Microglial Function in Brain Injury Microglia, the primary immune cells of the central nervous system, …

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Sex-related disparities in migraine recognition and management: insights from a tertiary headache center cohort
Understanding Sex-Related Disparities Sex-related disparities in healthcare often illustrate the differences in how male and…
Apathy and cognitive decline as the first presentation of SLE-associated vascular dementia: a case report
Case Presentation A 45-year-old woman, previously healthy with no history of psychiatric or neurological disorders,…
Revisiting motor inhibition in individuals with functional paralysis and spinal cord injury
Understanding Motor Inhibition Motor inhibition is a fundamental aspect of movement control, allowing individuals to…
Treatment of functional neurological disorder: an umbrella review of systematic reviews and meta-analyses
Treatment Approaches Treatment approaches for functional neurological disorder (FND) vary significantly given the complexity of…
Visualizing diagnostic delays in functional/dissociative seizures using the referral odyssey plot: A retrospective cohort study
Visualizing Diagnostic Delays In understanding how patients with functional or dissociative seizures navigate their healthcare…

Assessing knowledge and attitudes towards sports-related concussion among university students in Saudi Arabia: a cross-sectional study
CONCLUSION: Although university students in Saudi Arabia generally have good knowledge and attitudes towards concussion, there are notable gaps in symptom recognition and safe concussion behaviours. These findings highlight the need for targeted, region-specific concussion education programmes.
Stabilizing microtubules increases acute cellular injury at high strain rates
Mechanical strain is a key contributor to mild traumatic brain injury (mTBI), yet the impact of varying strain magnitudes and strain rates on cellular function and disease remain poorly understood. In this study, we examined acute membrane damage responses to mechanical strain in SH-SY5Y cells and the modulatory roles of tau phosphorylation and microtubule stability […]
Pre-injury sleep disturbance as a moderator of cognitive functioning in children and adolescents with mild traumatic brain injury
CONCLUSIONS: These results suggest that pre-existing sleep disturbances and mTBI are jointly associated with poorer executive functioning post-injury. Interventions to improve sleep might help mitigate the effects of mTBI on children's cognitive functioning.
Clinical Evaluation of the TBI Assay in a Representative Emergency Department Cohort
CONCLUSIONS: The TBI assay on the Alinity i platform demonstrated excellent sensitivity but showed limited specificity, particularly in patients >65 years. Our findings support the safe use of the TBI assay as a rule-out tool in the ED.
The Contribution of Aerospace Medicine Specialty Expertise in the Diagnosis and Treatment of Headache Disorders with Concomitant Clinically Symptomatic Dyscapnia (Respiratory Alkalosis/Acidosis)
PURPOSE OF REVIEW: A subset of patients with headache disorders presents with a dyscapnic state typically clinically symptomatic chronic respiratory alkalosis (CSCRA). CSCRA is well described as an important factor in increased neuromuscular irritability and reduces tissue oxygen delivery through reduction of cerebral blood flow (vasospasm) and left shift of the oxygen-hemoglobin dissociation curve, as […]