Tag:

neuronal damage

Dementia
Single-nucleus and spatial transcriptomic profiling of human temporal cortex and white matter reveals key associations with AD pathology

by myneuronews November 24, 2025

by myneuronews November 24, 2025

Study Overview This study centers on the intricate relationships between cellular profiles in the human …

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Traumatic brain injury
The kynurenine pathway in pediatric “mild-to-moderate” traumatic brain injury: translational insights from a prospective human study and a large-animal model

by myneuronews November 21, 2025

by myneuronews November 21, 2025

Kynurenine Pathway Mechanisms The kynurenine pathway is a critical metabolic route for the amino acid …

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Traumatic brain injury
Brain Ischemia Across Injury Severity in Traumatic Brain Injury and an Association with Abusive Head Trauma

by myneuronews November 21, 2025

by myneuronews November 21, 2025

Pathophysiology of Brain Ischemia Brain ischemia occurs when there is a deficiency of blood supply …

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Traumatic brain injury
Clinical Outcomes in the Patient With Traumatic Brain Injury and Comorbid Obesity: A Scoping Review

by myneuronews November 19, 2025

by myneuronews November 19, 2025

Clinical Outcomes in Traumatic Brain Injury Traumatic brain injury (TBI) represents a significant challenge in …

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Traumatic brain injury
Targeted complement inhibition ameliorates the pathological and cognitive outcomes in repetitive mild closed head injury

by myneuronews November 19, 2025

by myneuronews November 19, 2025

Study Overview The investigation into the effects of targeted complement inhibition on outcomes following repetitive …

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Traumatic brain injury
Metabolomics of cerebrospinal fluid following traumatic brain injury: Exploration of biomarkers for secondary injuries and severity

by myneuronews November 14, 2025

by myneuronews November 14, 2025

Biomarkers in cerebrospinal fluid analysis Cerebrospinal fluid (CSF) serves as a crucial medium for assessing …

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Traumatic brain injury
Metabolomics of cerebrospinal fluid following traumatic brain injury: Exploration of biomarkers for secondary injuries and severity

by myneuronews November 14, 2025

by myneuronews November 14, 2025

Metabolomic Profiling Metabolomic profiling involves the comprehensive analysis of metabolites—small molecules that are the end …

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Traumatic brain injury
Chronic Traumatic Encephalopathy Neuropathologic Change in Military Veterans

by myneuronews November 10, 2025

by myneuronews November 10, 2025

Pathophysiology of Chronic Traumatic Encephalopathy Chronic Traumatic Encephalopathy (CTE) is a degenerative brain disease commonly …

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Traumatic brain injury
Therapeutic VEGFC treatment provides protection against traumatic-brain-injury-driven tauopathy pathogenesis

by myneuronews November 8, 2025

by myneuronews November 8, 2025

Therapeutic Efficacy of VEGFC The treatment of traumatic brain injury (TBI) has been a significant …

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Traumatic brain injury
Beyond mild, moderate, and severe traumatic brain injury: modelling severity from clinical, neuroimaging, and blood-based indicators

by myneuronews November 5, 2025

by myneuronews November 5, 2025

Understanding Traumatic Brain Injury Severity Traumatic brain injury (TBI) manifests in varying degrees of severity, …

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Neuron-derived extracellular vesicles reflect adaptive neuronal responses to cortical spreading depolarization: a biomarker study for migraine
Study Overview This study investigates the role of neuron-derived extracellular vesicles (EVs) in the context…
Geriatric core competencies for non-geriatricians and nurses: a scoping review
Study Overview This scoping review aims to identify and categorize the core competencies necessary for…
Epidemiology of functional neurological disorder – The clinical spectrum
Epidemiological Trends in Functional Neurological Disorder Epidemiological studies indicate a rising prevalence of Functional Neurological…
Acupuncture for Mild Traumatic Brain Injury: A Call for Deeper Analysis of Symptoms and Scans
Understanding Acupuncture Acupuncture is a traditional Chinese medicine practice that has gained popularity worldwide as…
The Intensive Stroke Cycling for Optimal Recovery and Economic Value Trial (I-SCORE): Protocol for a Randomized Clinical Trial
Study Overview The Intensive Stroke Cycling for Optimal Recovery and Economic Value Trial (I-SCORE) is…

Intracranial Injury Caused by Transorbital Penetrating Trauma: An E-Scooter Brake Handle as an Unusual Culprit
Transorbital penetrating intracranial injuries are a rare but life-threatening subset of penetrating head traumas. While isolated cases caused by bicycle brake handles have been reported, often with fatal outcomes, this is the first documented case of such an injury caused by an electric scooter (e-scooter) brake handle. The objective is to present the unique management […]
The Influence of Aerobic Exercise Therapy on Patient-Reported Outcome Measures Following Concussion: A Scoping Review
Background/Objectives: The purpose of this scoping review was to identify the effects of exercise therapy on patient-reported outcome measure(s) (PROM(s)) after concussion, and to highlight the current knowledge gaps in the literature. Methods: A search of EMBASE, MEDLINE, SCOPUS, BIOSIS, and Cochrane Libraries was performed on 1 December 2023 (from database inception) and updated on […]
A Bioinformatic Study of Genetics Involved in Determining Mild Traumatic Brain Injury Severity and Recovery
Objectives: This in silico study sought to identify specific biomarkers for mild traumatic brain injury (mTBI) through the analysis of publicly available gene and miRNA databases, hypothesizing their influence on neuronal structure, axonal integrity, and regeneration. Methods: This study implemented a three-step process: (1) data searching for mTBI-related genes in Gene and MalaCard databases and […]
Concussion-Related Cognitive and Lipid Changes in Retired UK Rugby Players Study
Long-term effects of concussions, particularly in contact sport athletes, have been linked to changes in neuronal health. Lipid dysregulation has emerged as a potential contributor to neuronal injury and may serve as a measurable biomarker of brain pathology. This study investigated cognitive scores and serum lipid biomarkers in retired rugby players with a history of […]
Harmonisation and implementation of sports-related concussion guidelines in European youth football: the REFORM Erasmus+ project
INTRODUCTION: Sports-related concussions (SRCs) are frequently under-reported in youth sports, especially football, due to limited awareness, inconsistent reporting practices and a lack of medical personnel at the grassroots level. Concussion management protocols vary widely across regions, highlighting the need for a standardised approach. This study aims to harmonise SRC education and management practices in European […]