Neuromyelitis optica spectrum disorder presenting as rapidly progressive dementia: A case report
Case Presentation The subject of this case report is a 58-year-old female who presented with a strikingly rapid onset of […]
Role of microglia in neuromyelitis optica (Review)
Microglia Function in Neuromyelitis Optica Microglia are specialized immune cells residing in the central nervous system, crucial for maintaining neuronal
Role of microglia in neuromyelitis optica (Review) Read Post »
Targeting P2Y12 limits TH17 accumulation in the CNS and reduces EAE progression
Study Overview This investigation focuses on the role of P2Y12, a nucleoside triphosphate receptor that is part of the purinergic
Targeting P2Y12 limits TH17 accumulation in the CNS and reduces EAE progression Read Post »
Enkephalin Treatment Reduces Elevated Brain Glia in Mice With Experimental Autoimmune Encephalomyelitis
Study Overview In recent studies, the role of enkephalins, which are endogenous opioid peptides, has gained attention due to their
Possible Structural and Biochemical Impact of Blast-Induced Traumatic Brain Injury on the Hypothalamus and Its Homeostatic Implications
Impact of Blast-Induced Injuries on Brain Structure Blast-induced traumatic brain injury (TBI) significantly alters the structural integrity of the brain,
Effect of Repetitive Transcranial Magnetic Stimulation (rTMS) on Serum Neurofilament Light Chain (sNfL) and its Correlation to Cognitive Function in Multiple Sclerosis
Background and Rationale The research surrounding repetitive transcranial magnetic stimulation (rTMS) has gained significant traction in recent years, particularly regarding
Patient-Informed Biomechanical Modeling Reveals Mechanical Mechanism of Brain Damage in Idiopathic Normal Pressure Hydrocephalus
Mechanical Mechanisms of Brain Damage Brain damage in conditions like idiopathic normal pressure hydrocephalus (iNPH) has been increasingly understood through
Mitochondrial metabolic remodeling and blood-brain barrier dysfunction after repetitive mild traumatic brain injury
Mitochondrial Dysfunction After Injury Mitochondrial dysfunction is a significant consequence of repetitive mild traumatic brain injury (mTBI). The mitochondria, often
Exploring FOXO3a in cuprizone-induced demyelination: insight into its association with berberine-mediated modulation of AMPK/SIRT1 and IL-6/STAT3 signaling
Study Overview The investigation into the role of FOXO3a during demyelination processes induced by cuprizone has unveiled significant insights into
Seizures and epilepsy in MOG antibody-associated disease: from cortical neuroimmunology to clinical practice
Pathophysiology of MOG Antibody-Associated Disease MOG antibody-associated disease (MOGAD) is characterized by the presence of antibodies against myelin oligodendrocyte glycoprotein