Tag:

neuronal damage

Traumatic brain injury
Single-Cell RNA and Transcriptome Sequencing to Analyze the Role of Lactate Metabolism in Traumatic Brain Injury Astrocytes

by myneuronews May 21, 2025

by myneuronews May 21, 2025

Role of Lactate Metabolism in Astrocytes Lactate metabolism plays a pivotal role in cellular energy …

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Traumatic brain injury
Blood-Based Biomarkers for Improved Characterization of Traumatic Brain Injury: Recommendations from the 2024 National Institute for Neurological Disorders and Stroke Traumatic Brain Injury Classification and Nomenclature Initiative Blood-Based Biomarkers Working Group

by myneuronews May 20, 2025

by myneuronews May 20, 2025

Biomarker Identification and Validation The identification and validation of biomarkers for traumatic brain injury (TBI) …

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Traumatic brain injury
Imaging a concussion and the ensuing immune response at the blood-brain barrier

by myneuronews May 19, 2025

by myneuronews May 19, 2025

Understanding the Blood-Brain Barrier The blood-brain barrier (BBB) is a highly selective permeability barrier that …

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Headaches
Neurological complications of orthopoxvirus infections: neurotropism and neurovirulence

by myneuronews May 15, 2025

by myneuronews May 15, 2025

Neurological Manifestations in Orthopoxvirus Infection Orthopoxvirus infections are associated with a variety of neurological manifestations …

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Traumatic brain injury
Sensory driven neurophysiological mechanisms of concussion: a parsimonious and falsifiable theory

by myneuronews May 15, 2025

by myneuronews May 15, 2025

Overview of Neurophysiological Mechanisms Understanding the neurophysiological mechanisms underlying concussion involves delving into the complex …

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Traumatic brain injury
Cellular and molecular mechanisms of pathological tau phosphorylation in traumatic brain injury: implications for chronic traumatic encephalopathy

by myneuronews May 10, 2025

by myneuronews May 10, 2025

Pathological Tau Phosphorylation Mechanisms Tau protein is a key player in maintaining the structural integrity …

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Dementia
Temporal transcriptomic changes in the THY-Tau22 mouse model of tauopathy display cell type- and sex-specific differences

by myneuronews May 7, 2025

by myneuronews May 7, 2025

Study Overview The study investigates the temporal changes in gene expression occurring in the brains …

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Traumatic brain injury
Diffusion Tensor Image Analysis Along the Perivascular Space in Former Professional Athletes with Repetitive Mild Traumatic Brain Injury History

by myneuronews May 3, 2025

by myneuronews May 3, 2025

Background and Rationale Understanding the implications of repetitive mild traumatic brain injuries (mTBIs) is essential, …

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Traumatic brain injury
Hybrid membrane-coated Cyclosporine A nanocrystals preventing secondary brain injury via alleviating neuroinflammatory and oxidative stress

by myneuronews May 1, 2025

by myneuronews May 1, 2025

Study Overview This study explores the effectiveness of hybrid membrane-coated cyclosporine A (CsA) nanocrystals in …

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Traumatic brain injury
Effects of Subanesthetic Intravenous Ketamine Infusion on Stress Hormones and Synaptic Density in Rats with Mild Closed-Head Injury

by myneuronews April 29, 2025

by myneuronews April 29, 2025

Effects of Ketamine on Stress Hormones Research on the impact of ketamine, particularly in its …

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Symptom Exacerbation With Physical and Mental Activity and the Association With Clinical Outcomes After Sport-Related Concussion in Youth and Adults
CONCLUSIONS: These results demonstrate a potential physiological link between CSp and VOR deficits with self-reported symptom exacerbation during physical and mental activity, respectively. Future research is warranted to delineate the neurophysiological basis of these findings.
Updated Status of Physical Activity Research for People With Traumatic Brain Injury
CONCLUSIONS: The greater number of studies in Phases 3 and 4 suggest the field has evolved in 12 years. The lack of progress in Phase 5 provides opportunity for implementation science efforts. Recommendations for physical activity behavior research after msTBI are discussed.
Clinical Cut Point for the Post Concussion Symptom Inventory Following Adolescent Concussion
CONCLUSIONS: Our results suggest a PCSI cut point of 23 can distinguish between adolescents with/without a recent concussion and may provide enhanced accuracy to identify a suspected concussion in the subacute time after injury.
Driving After Concussion: The Influence of Days Since Concussion on Simulated Driving Performance Recovery
CONCLUSIONS: Clinicians should consider recommendations that support limited driving during the acute stages (24-72 hours) of concussion followed by a gradual return to driving. A longitudinal study design in a larger sample is needed to better define driving performance recovery following concussion.
Sex Differences in Severity and Recovery Following Mild Traumatic Brain Injury: A Systematic Review
Background: Sex-based variations in brain structure, hormonal balance, and neurochemistry may influence symptom presentation and recovery after mild traumatic brain injury (mTBI). This systematic review investigated sex-related differences in mTBI severity, symptoms, and recovery outcomes across different injury mechanisms. Methods: This review followed PRISMA 2020 guidelines and was registered with PROSPERO (CRD420251011379). Searches were conducted […]