Tag:

neuronal damage

Functional neurological disorders
AAV-based gene therapy ameliorates neurological deficits in a mouse model of childhood-onset neurodegeneration with cerebellar atrophy (CONDCA)

by myneuronews August 4, 2025

by myneuronews August 4, 2025

Study Summary The study investigates the efficacy of adeno-associated virus (AAV)-based gene therapy in a …

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Dementia
Embracing the Modern Biochemistry of Brain Metabolism

by myneuronews July 21, 2025

by myneuronews July 21, 2025

Understanding Brain Metabolism The brain is an extraordinarily energy-demanding organ, consuming approximately 20% of the …

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Traumatic brain injury
Neurobiology and Impact of Chronic Traumatic Encephalopathy in Athletes: A Focused Review

by myneuronews July 21, 2025

by myneuronews July 21, 2025

Neurobiological Mechanisms Chronic Traumatic Encephalopathy (CTE) is a progressive neurodegenerative disease primarily associated with repeated …

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Functional neurological disorders
Integrated Single-Cell and Spatial Transcriptomic Analysis Identifies ISR-Related Genes Driving Immune Regulation in Parkinson’s Disease

by myneuronews July 21, 2025

by myneuronews July 21, 2025

Integrated Transcriptomic Approaches The integration of transcriptomic approaches offers a powerful way to glean insights …

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Traumatic brain injury
Inhibition of microglia priming by NLRP3 reduces the impact of early life stress and mild TBI

by myneuronews July 17, 2025

by myneuronews July 17, 2025

Study Overview The objective of the research was to investigate how inhibiting the activation of …

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Traumatic brain injury
Brain biomarker profiles vary with semi-synthetic and grain-based diets in healthy and mTBI mice

by myneuronews July 16, 2025

by myneuronews July 16, 2025

Brain Biomarker Profiles Recent studies have highlighted the importance of brain biomarker profiles in understanding …

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Functional neurological disorders
Luminal Vascular Dysfunction Drives Rapid Blood Brain Barrier Injury in Hyperglycemic Stroke: Key Roles for Luminal Glycocalyx and Complement

by myneuronews July 16, 2025

by myneuronews July 16, 2025

Luminal Vascular Dysfunction as a Mechanism In examining how luminal vascular dysfunction contributes to blood-brain …

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Functional neurological disorders
Luminal Vascular Dysfunction Drives Rapid Blood Brain Barrier Injury in Hyperglycemic Stroke: Key Roles for Luminal Glycocalyx and Complement

by myneuronews July 16, 2025

by myneuronews July 16, 2025

Luminal Glycocalyx and Its Role in Blood Brain Barrier Integrity The luminal glycocalyx is a …

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Functional neurological disorders
Identifying pyroptosis- and inflammation-related genes in spinal cord injury based on bioinformatics analysis

by myneuronews July 14, 2025

by myneuronews July 14, 2025

Gene Identification Methods To identify genes that play a role in pyroptosis and inflammation following …

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Traumatic brain injury
Integrative Constraint-Based Modeling and Proteomics Uncover Astrocytic Metabolic Adaptations to the Post-TBI Microenvironment

by myneuronews July 12, 2025

by myneuronews July 12, 2025

Study Overview The research explores the metabolic responses of astrocytes, a type of glial cell …

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Nasopharyngeal Giant Carcinoma Mimicking Intracranial Lesions: A Case Report and Literature Review
Study Overview The presented case report addresses the complexities of diagnosing nasopharyngeal giant carcinoma, particularly…
Process evaluation of a digital health intervention for dementia caregivers: Integrating active and passive measurements
Intervention Description The digital health intervention designed for dementia caregivers is a multifaceted program aimed…
Authors’ Response to: Advocating for Focused Attention on Functional Neurological Disorder in the Undergraduate Medical School Curriculum
Understanding Functional Neurological Disorder Functional Neurological Disorder (FND) presents a fascinating intersection of neurology and…
Subtype shift, relapse rate and risk factors of frequent relapse in cluster headache: A multicenter, prospective, longitudinal observation
Study Overview The study focused on understanding the various types of cluster headaches, examining the…
Quercetin as a Multi-Target Natural Therapeutic in Aging-Related Diseases: Systemic Molecular and Cellular Mechanisms
Mechanisms of Action Quercetin, a flavonoid found abundantly in many fruits, vegetables, and beverages, exhibits…

Patterns of Post-Concussive Symptoms Following Mild Traumatic Brain Injury: Longitudinal Data in Children and Adults to Examine Sex Differences Across the Life Span
OBJECTIVE: To examine sex- and age-related differences in patterns of post-concussive symptoms (PCS), across cognitive, somatic, emotional, and behavioral domains, and their recovery within the first 6 months after mild traumatic brain injury (mTBI), and their relation to participation.
Connecting the Dots: The Role of Pediatric Concussion on Pubertal Hormones and Psychological Health
PURPOSE: Psychological health issues resulting from emotional dysregulation such as anxiety and depression following pediatric concussion are a public health concern, but the underlying mechanisms remain unclear. Puberty opens a window of vulnerability for emotion dysregulation and a link between pediatric concussion and hormonal deficits has been reported. We investigated the association between pubertal hormones […]
Research Letter: Safety, Feasibility, Acceptability and Preliminary Findings From Veterans' Intervention Blending NeuRomodulation and YogA for Chronic PaiN Treatment: VIBRANT-MTBI and Chronic Pain Pilot
CONCLUSIONS: Lack of serious adverse events suggests that the iTBS + LYByoga intervention is safe among veterans with mTBI + CP. The program's feasibility and acceptability coupled with improvements in self-reported pain outcomes warrants further research in a larger, randomized control trial.
Examination of the Association Between History of Self-Reported Mild Traumatic Brain Injury and Neurocognitive Performance
CONCLUSION: After adjusting for demographic and genetic factors, no significant differences were found between children with mTBI and OI/NI. The findings highlight the importance of accounting for demographic, socioeconomic, and genetic confounders, as well as selecting appropriate control groups, when analyzing cognitive differences of children with mTBI.
Post-Acute COVID-19 Syndrome: Brain Fog Phenotype, Patient Centric Understanding and Biopsychosocial Oriented Treatment
Post-Acute COVID-19 syndrome (PACS), a term used to describe ongoing symptoms following SARS-CoV2 (COVID-19) infection, includes prominent neuropsychological sequela, such as a subjective sense of brain fog. Brain fog can be persistent and interfere with quality of life and daily functioning across multiple domains. Rehabilitation professionals can comprehensively address PACS-related brain fog through a biopsychosocial […]