ACSL4-mediated astrocyte ferroptosis augments neuroinflammation and exacerbates NMOSD pathology
Ferroptosis in Astrocytes Ferroptosis is a unique form of regulated cell death characterized by the accumulation of iron-dependent lipid peroxides […]
ACSL4-mediated astrocyte ferroptosis augments neuroinflammation and exacerbates NMOSD pathology
Study Overview The research presented in this article delves into the significant role of astrocyte ferroptosis in the context of
Astrocytic TIA1-Mediated Stress Granules Promote the Demyelination of Optic Neuritis by Sequestering mRNA of Cholesterol Synthesis Genes in an Experimental Autoimmune Encephalomyelitis Model
Mechanisms of Astrocytic TIA1-Mediated Stress Granules Astrocytes, the predominant glial cells in the central nervous system, play a pivotal role
Extracellular Vesicle-Based Biomarkers in Spinal Cord Injury: A State-of-the-Art Review on Diagnostic and Prognostic Advances
Extracellular Vesicles in Spinal Cord Injury Extracellular vesicles (EVs) have emerged as pivotal players in cell communication and biomarker discovery,
Oligodendrocytes Are Active Participants in the Pathogenesis of Multiple Sclerosis and Its Animal Models
Role of Oligodendrocytes in Multiple Sclerosis Oligodendrocytes, the myelinating cells of the central nervous system (CNS), play a crucial role
Emerging Roles, Mechanisms, and Therapeutic Potential of Thyroid Hormones in Neurodegenerative Diseases: A Review
Thyroid Hormones and Neurodegeneration Thyroid hormones, primarily thyroxine (T4) and triiodothyronine (T3), play a crucial role in regulating various biological
Astragalus polysaccharide ameliorates neuroinflammation in EAE mice by modulating microglial autophagy to reduce lipid droplet accumulation
Study Overview The research investigates the effects of Astragalus polysaccharide, a natural compound derived from the Astragalus plant, on neuroinflammation
Quantifying Mechanical Strain-Induced Membrane Damage in Early Neuronal Cells Using an In Vitro Traumatic Brain Injury Model
Study Overview In this study, researchers aimed to investigate the impact of mechanical strain on neuronal cells, particularly during traumatic
Quantifying Mechanical Strain-Induced Membrane Damage in Early Neuronal Cells Using an In Vitro Traumatic Brain Injury Model
Study Overview The study focuses on the impact of mechanical strain on early neuronal cells, specifically looking at how traumatic
Loss of CAMKK2 and iron-transport proteins-transferrin and its receptor-in the Alzheimer’s disease hippocampus: link to tau pathology
Loss of CAMKK2 in Alzheimer’s Disease The loss of calcium/calmodulin-dependent protein kinase kinase 2 (CAMKK2) has been linked to several