Tag:

neuronal damage

Traumatic brain injury
Brain biomarker profiles vary with semi-synthetic and grain-based diets in healthy and mTBI mice

by myneuronews July 16, 2025

by myneuronews July 16, 2025

Brain Biomarker Profiles Recent studies have highlighted the importance of brain biomarker profiles in understanding …

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Functional neurological disorders
Identifying pyroptosis- and inflammation-related genes in spinal cord injury based on bioinformatics analysis

by myneuronews July 14, 2025

by myneuronews July 14, 2025

Gene Identification Methods To identify genes that play a role in pyroptosis and inflammation following …

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Traumatic brain injury
Integrative Constraint-Based Modeling and Proteomics Uncover Astrocytic Metabolic Adaptations to the Post-TBI Microenvironment

by myneuronews July 12, 2025

by myneuronews July 12, 2025

Study Overview The research explores the metabolic responses of astrocytes, a type of glial cell …

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Functional neurological disorders
Role of ALOX5AP in the pathogenesis of cerebral small vessel disease: impact of inflammation and lipid metabolism dysregulation

by myneuronews July 12, 2025

by myneuronews July 12, 2025

Pathophysiological Mechanisms of ALOX5AP ALOX5AP (Arachidonate 5-Lipoxygenase-Activating Protein) plays a pivotal role in the pathophysiology …

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Functional neurological disorders
Wogonin Inhibits Oxidative Stress in Hypoxia-Induced hCMEC/D3 Cells Through Suppressing CXCL8-Mediated TLR4/NF-κB Pathway

by myneuronews July 4, 2025

by myneuronews July 4, 2025

Mechanisms of Wogonin Action Wogonin, a naturally occurring flavonoid derived from the plant Scutellaria baicalensis, …

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Functional neurological disorders
Unveiling cortical criticality changes along the prodromal to the overt continuum of alpha-synucleinopathy

by myneuronews July 3, 2025

by myneuronews July 3, 2025

Cortical Criticality in Alpha-Synucleinopathy The concept of cortical criticality refers to the brain’s ability to …

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Traumatic brain injury
Aldehydic load as an objective imaging biomarker of mild traumatic brain injury

by myneuronews July 3, 2025

by myneuronews July 3, 2025

Aldehydic Load Measurement The measurement of aldehydic load plays a crucial role in understanding the …

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Traumatic brain injury
Neurobiomarkers for Traumatic Brain Injury: Comparison of Serum Values Within 24 Hours of Injury With Glasgow Coma Scale (GCS) Scores in a Prospective Cohort Trial

by myneuronews July 2, 2025

by myneuronews July 2, 2025

Neurobiomarkers in Traumatic Brain Injury Neurobiomarkers represent measurable indicators located in the body, which provide …

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Traumatic brain injury
Biomarker evidence of neurodegeneration in mid-life former rugby players

by myneuronews July 2, 2025

by myneuronews July 2, 2025

Neurodegeneration Biomarkers Biomarkers indicative of neurodegeneration are crucial for understanding the underlying processes affecting brain …

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Traumatic brain injury
Multimodal Magnetic Resonance Imaging with Mild Repetitive Head Injury in Awake Rats: Modeling the Human Experience and Clinical Condition

by myneuronews June 29, 2025

by myneuronews June 29, 2025

Study Overview This study investigates the effects of mild repetitive head injuries on brain function …

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Neuron-derived extracellular vesicles reflect adaptive neuronal responses to cortical spreading depolarization: a biomarker study for migraine
Study Overview This study investigates the role of neuron-derived extracellular vesicles (EVs) in the context…
Geriatric core competencies for non-geriatricians and nurses: a scoping review
Study Overview This scoping review aims to identify and categorize the core competencies necessary for…
Epidemiology of functional neurological disorder – The clinical spectrum
Epidemiological Trends in Functional Neurological Disorder Epidemiological studies indicate a rising prevalence of Functional Neurological…
Acupuncture for Mild Traumatic Brain Injury: A Call for Deeper Analysis of Symptoms and Scans
Understanding Acupuncture Acupuncture is a traditional Chinese medicine practice that has gained popularity worldwide as…
The Intensive Stroke Cycling for Optimal Recovery and Economic Value Trial (I-SCORE): Protocol for a Randomized Clinical Trial
Study Overview The Intensive Stroke Cycling for Optimal Recovery and Economic Value Trial (I-SCORE) is…

Intracranial Injury Caused by Transorbital Penetrating Trauma: An E-Scooter Brake Handle as an Unusual Culprit
Transorbital penetrating intracranial injuries are a rare but life-threatening subset of penetrating head traumas. While isolated cases caused by bicycle brake handles have been reported, often with fatal outcomes, this is the first documented case of such an injury caused by an electric scooter (e-scooter) brake handle. The objective is to present the unique management […]
The Influence of Aerobic Exercise Therapy on Patient-Reported Outcome Measures Following Concussion: A Scoping Review
Background/Objectives: The purpose of this scoping review was to identify the effects of exercise therapy on patient-reported outcome measure(s) (PROM(s)) after concussion, and to highlight the current knowledge gaps in the literature. Methods: A search of EMBASE, MEDLINE, SCOPUS, BIOSIS, and Cochrane Libraries was performed on 1 December 2023 (from database inception) and updated on […]
A Bioinformatic Study of Genetics Involved in Determining Mild Traumatic Brain Injury Severity and Recovery
Objectives: This in silico study sought to identify specific biomarkers for mild traumatic brain injury (mTBI) through the analysis of publicly available gene and miRNA databases, hypothesizing their influence on neuronal structure, axonal integrity, and regeneration. Methods: This study implemented a three-step process: (1) data searching for mTBI-related genes in Gene and MalaCard databases and […]
Concussion-Related Cognitive and Lipid Changes in Retired UK Rugby Players Study
Long-term effects of concussions, particularly in contact sport athletes, have been linked to changes in neuronal health. Lipid dysregulation has emerged as a potential contributor to neuronal injury and may serve as a measurable biomarker of brain pathology. This study investigated cognitive scores and serum lipid biomarkers in retired rugby players with a history of […]
Harmonisation and implementation of sports-related concussion guidelines in European youth football: the REFORM Erasmus+ project
INTRODUCTION: Sports-related concussions (SRCs) are frequently under-reported in youth sports, especially football, due to limited awareness, inconsistent reporting practices and a lack of medical personnel at the grassroots level. Concussion management protocols vary widely across regions, highlighting the need for a standardised approach. This study aims to harmonise SRC education and management practices in European […]