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neurons

Traumatic brain injury
Inhibition of TRPM3 channels in the medial prefrontal cortex mitigates OCD symptoms following traumatic brain injury

by myneuronews May 15, 2025

by myneuronews May 15, 2025

TRPM3 Channel Function in the Brain The TRPM3 channel, a member of the transient receptor …

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Traumatic brain injury
Correction: Cerebral Haemodynamic Assessment Following Sport-related Concussion (Mild Traumatic Brain Injury) in Youth and Amateur Rugby Union Players

by myneuronews May 13, 2025

by myneuronews May 13, 2025

Cerebral haemodynamics in concussion Cerebral haemodynamics refers to the dynamics of blood flow within the …

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Dementia
Intranasal Delivery of BACE1 siRNA and Berberine via Engineered Stem Cell Exosomes for the Treatment of Alzheimer’s Disease

by myneuronews May 12, 2025

by myneuronews May 12, 2025

Treatment Strategy Overview In recent years, the exploration of innovative approaches to treat Alzheimer’s disease …

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Traumatic brain injury
Cellular and molecular mechanisms of pathological tau phosphorylation in traumatic brain injury: implications for chronic traumatic encephalopathy

by myneuronews May 10, 2025

by myneuronews May 10, 2025

Pathological tau phosphorylation mechanisms Tau is a critical protein in the brain, primarily known for …

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Traumatic brain injury
Cellular and molecular mechanisms of pathological tau phosphorylation in traumatic brain injury: implications for chronic traumatic encephalopathy

by myneuronews May 10, 2025

by myneuronews May 10, 2025

Pathological Tau Phosphorylation Mechanisms Tau protein is a key player in maintaining the structural integrity …

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Dementia
Temporal transcriptomic changes in the THY-Tau22 mouse model of tauopathy display cell type- and sex-specific differences

by myneuronews May 7, 2025

by myneuronews May 7, 2025

Study Overview The study investigates the temporal changes in gene expression occurring in the brains …

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Traumatic brain injury
PACAP a mediator of inflammation following trauma exposure and mild traumatic brain injury: Differential effects in males and females

by myneuronews May 1, 2025

by myneuronews May 1, 2025

Background on PACAP and Inflammation Pituitary adenylate cyclase-activating polypeptide (PACAP) is a neuropeptide that plays …

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Traumatic brain injury
Hybrid membrane-coated Cyclosporine A nanocrystals preventing secondary brain injury via alleviating neuroinflammatory and oxidative stress

by myneuronews May 1, 2025

by myneuronews May 1, 2025

Therapeutic Approach The therapeutic strategy explored in this study focuses on utilizing hybrid membrane-coated nanocrystals …

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Traumatic brain injury
PACAP a mediator of inflammation following trauma exposure and mild traumatic brain injury: Differential effects in males and females

by myneuronews May 1, 2025

by myneuronews May 1, 2025

Overview of PACAP and Inflammation Pituitary adenylate cyclase-activating polypeptide (PACAP) is a neuropeptide that plays …

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Traumatic brain injury
PIRACETAM HELPS RESTORE VISION AFTER CRANIOCEREBRAL TRAUMA

by myneuronews April 30, 2025

by myneuronews April 30, 2025

Piracetam Mechanism of Action Piracetam, a member of the racetam family of nootropic compounds, is …

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Subjective symptoms of functional/dissociative seizures and their diagnostic value: A systematic review
Study Overview The research conducted offers a comprehensive examination of the subjective symptoms associated with…
Patient Perspective: Closing the Gap: Personal and Clinical Reflections on Functional Neurologic Disorder
Patient Experience The journey of individuals dealing with functional neurologic disorder (FND) is often marked…
Is It Psychogenic Non-Epileptic Event, Sleep Related Rhythmical Movement Disorder or Hypermotor Seizure?
Diagnostic Criteria To accurately identify psychogenic non-epileptic events (PNEE), sleep-related rhythmical movement disorders (RMD), and…
Downregulation of neuronal DRD2 drives microglia synaptic pruning and results in cognitive deficits by promoting CCL2 release in a rat model of chronic migraine
Study Overview This research investigates the role of dopamine receptor D2 (DRD2) in neurons and…
A videoconferencing group-based psychoeducation for family caregivers of people living with dementia: a feasibility study
Study Overview This study explored the feasibility of conducting videoconferencing group-based psychoeducation specifically tailored for…

Benchmarking mobilization practice and functional outcomes in traumatic brain injury patients admitted to the intensive care unit: a three-year service evaluation
CONCLUSION: Acute TBI patients admitted to the ICU at our institution had low rates of mobilization and achieved low levels of mobility at ICU discharge. This service evaluation highlights the need for prospective studies into early mobilization practices in the neurotrauma ICU.
Cognitive and neurobehavioral phenotypes of post 9/11 veterans with epilepsy and mild traumatic brain injury
INTRODUCTION: Traumatic brain injury (TBI) and epilepsy are significant health concerns among the veteran population, but the links between mild TBI and cognitive and behavioral changes in epilepsy have been little explored. This study leveraged natural language processing of medical records and chart review to assess the prevalence and patterns of cognitive and behavioral symptoms […]
Resting-state EEG and machine learning to investigate cortical connectivity as a biomarker in chronic mTBI
INTRODUCTION: Mild traumatic brain injury (mTBI) is a heterogeneous condition with long-term sequelae, yet diagnosis in the chronic stage remains limited by reliance on acute criteria and subjective reports. Objective biomarkers are needed, as current blood-based markers show diagnostic value primarily in the acute and subacute phases. Resting-state EEG (RS-EEG) can capture large-scale network disruptions […]
Family functioning and caring for a child with acquired brain injury: a systematic review and thematic analysis
CONCLUSIONS: Family functioning after pABI can only be fully understood if multiple interconnected psychosocial and practical aspects are considered. Most included studies were of low-to-moderate quality, limiting the reliability, validity, and generalizability of the findings. Nonetheless, the conceptual model could provide a framework for understanding family functioning and enhancing outcomes for pABI.
Associations of smoking, infections, early-life exposures, and concussion with progressive-onset versus relapse-onset multiple sclerosis: A case-control study
CONCLUSIONS: PPMS shares some common risk factors with RMS, such as tobacco smoking and infectious mononucleosis, with similar effect sizes. This suggests PPMS and RMS may share underlying disease mechanisms. Further studies are needed to validate the role of other factors associated with PPMS onset.