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neurons

Functional neurological disorders
Expanding the Phenotypic Spectrum Associated with DPH5-Related Diphthamide Deficiency

by myneuronews July 29, 2025

by myneuronews July 29, 2025

Phenotypic Spectrum of DPH5 Deficiency DPH5 deficiency is a rare genetic condition that impacts the …

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Dementia
Unveiling blood biomarkers for neuronal hyperplasticity: Insights from AD molecular subtyping, a comprehensive review

by myneuronews July 25, 2025

by myneuronews July 25, 2025

Study Overview The research focuses on the exploration of blood biomarkers that indicate neuronal hyperplasticity, …

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Dementia
Cortical inhibitory and facilitatory alterations in the continuum of alpha-synucleinopathies

by myneuronews July 25, 2025

by myneuronews July 25, 2025

Cortical Inhibition in Alpha-Synucleinopathies Alterations in cortical inhibition have been observed in alpha-synucleinopathies, which include …

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Functional neurological disorders
The Frmpd3 Protein Regulates Susceptibility to Epilepsy by Combining with GRIP and GluA2

by myneuronews July 23, 2025

by myneuronews July 23, 2025

Role of Frmpd3 in Epilepsy The study presents compelling evidence that Frmpd3 plays a significant …

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Functional neurological disorders
The Frmpd3 Protein Regulates Susceptibility to Epilepsy by Combining with GRIP and GluA2

by myneuronews July 23, 2025

by myneuronews July 23, 2025

Frmpd3 Function in Epilepsy The study of the Frmpd3 protein reveals its significant role in …

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Dementia
Embracing the Modern Biochemistry of Brain Metabolism

by myneuronews July 21, 2025

by myneuronews July 21, 2025

Understanding Brain Metabolism The brain is an extraordinarily energy-demanding organ, consuming approximately 20% of the …

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Headaches
Anti-nociceptive action of leonurine through TRPA1 and TRPV4 channels modulation

by myneuronews July 21, 2025

by myneuronews July 21, 2025

Anti-nociceptive Mechanisms Leonurine, a bioactive compound derived from the plant Leonurus japonicus, exhibits significant anti-nociceptive …

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Functional neurological disorders
Integrated Single-Cell and Spatial Transcriptomic Analysis Identifies ISR-Related Genes Driving Immune Regulation in Parkinson’s Disease

by myneuronews July 21, 2025

by myneuronews July 21, 2025

Integrated Transcriptomic Approaches The integration of transcriptomic approaches offers a powerful way to glean insights …

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Functional neurological disorders
OCNDS core features are conserved across variants, with loop-region mutations driving greater symptom burden

by myneuronews July 18, 2025

by myneuronews July 18, 2025

Core Features of OCNDS OCNDS, or Obsessive-Compulsive and Nervous System Disorders, presents a set of …

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Dementia
Cognitive Function, Physical Activity, and Sweat Cytokines in Older Adults With Dementia

by myneuronews July 18, 2025

by myneuronews July 18, 2025

Cognitive Function Assessment Assessing cognitive function in older adults, especially those with dementia, involves various …

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Development of chronic subdural haematoma from mild head injury: A case report and review of current Malaysian guidelines on traumatic brain injury
Delayed chronic subdural haematoma (cSDH) is a common but potentially serious complication following traumatic brain injury (TBI). Mild TBIs are commonly managed by primary care providers (PCPs), particularly in large, resource-limited settings such as Malaysia, where access to tertiary neurosurgical services may be delayed. Early identification of red-flag signs and symptoms and timely referrals are […]
Cognitive Proficiency after Traumatic Brain Injury in Children
Fifty-five children and adolescents with complicated mild-severe traumatic brain injury (TBI) completed the Wechsler Intelligence Scale for Children-Fifth Edition (WISC-V; Wechsler, 2014) within 1 to 12 months post-injury. Compared with demographically matched neurologically healthy controls, selected from the WISC-V standardization sample, participants with TBI demonstrated statistically significantly lower scores across WISC-V indices. The working memory, […]
Implementing Goal Attainment Scaling as a Person-Centered Measurement Tool to Direct Care and Evaluate Outcomes in Neurorehabilitation Settings
The purpose of this Special Communication is to describe barriers and facilitators to implementing goal attainment scaling (GAS) as a patient-centered measurement tool in neurorehabilitation settings. The experiences of three distinct neurorehabilitation settings that implemented GAS to enhance person-centered care and measure person-centered goal attainment are described: a neurorehabilitation service at an inpatient rehabilitation facility; […]
Construct Validity of the Tower of London Test: Generating a Construct Specification Equation Relating Problem Characteristics to Problem Difficulty in a Sample of Veterans with Mild Traumatic Brain Injury
The Tower of London (TOL) is a set of problem-solving tasks that are commonly used to measure cognition. No studies have developed construct specification equations (CSEs) to mathematically quantify how the characteristics of test problems relate to the difficulty of the problem in the TOL. We aimed to investigate the relationship between TOL problem characteristics […]
Vibrational spectroscopy methods reveal biochemical changes associated with the glial scar formation after traumatic brain injury
Traumatic brain injury (TBI) is a serious clinical and social problem. Millions of TBI cases, that require hospitalization and consequently burden social security systems, are reported each year. Analysis of the time course of changes that occur in the brain after primary injury may help indicate therapeutic goals and treatment directions that will minimize severe […]