Tag:

neurons

Dementia
Differences in inflammatory markers, mitochondrial function, and synaptic proteins in male and female Alzheimer’s disease post mortem brains

by myneuronews October 1, 2025

by myneuronews October 1, 2025

Inflammatory Markers Comparison Research into Alzheimer’s disease has increasingly highlighted the significance of inflammation in …

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Traumatic brain injury
Blocking axon-glial mechanotransduction to prevent concussive brain injury

by myneuronews September 30, 2025

by myneuronews September 30, 2025

Study Overview The research focuses on preventing concussive brain injuries through the inhibition of mechanotransduction …

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Traumatic brain injury
Neurogranin as a Synaptic Biomarker in Mild Traumatic Brain Injury: A Systematic Review of Diagnostic and Pathophysiological Evidence

by myneuronews September 22, 2025

by myneuronews September 22, 2025

Neurogranin as a Biomarker Neurogranin is a neuronal protein that has garnered attention as a …

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Dementia
Maintenance of neuronal TDP-43 expression requires axonal lysosome transport

by myneuronews September 19, 2025

by myneuronews September 19, 2025

Study Overview The investigation centered on understanding the critical role of TDP-43, a protein associated …

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Dementia
Quercetin as a Multi-Target Natural Therapeutic in Aging-Related Diseases: Systemic Molecular and Cellular Mechanisms

by myneuronews September 13, 2025

by myneuronews September 13, 2025

Mechanisms of Action Quercetin, a flavonoid found abundantly in many fruits, vegetables, and beverages, exhibits …

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Traumatic brain injury
Concussive injuries induce neuronal stress-dependent tau mislocalization to dendritic spines with acrolein and functional network alteration in TBI-on-a-chip

by myneuronews September 11, 2025

by myneuronews September 11, 2025

Study Overview This research focuses on the cellular mechanisms involved in concussive injuries, specifically examining …

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Traumatic brain injury
CD300f enables microglial damage sensing, efferocytosis, and apoptotic cell metabolization after brain injury

by myneuronews September 11, 2025

by myneuronews September 11, 2025

Microglial Function in Brain Injury Microglia, the primary immune cells of the central nervous system, …

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Dementia
Association Between Dietary Biotin Intake and Dementia Risk, Including Alzheimer’s Disease: A Prospective Study of 122 959 UK Biobank Participants

by myneuronews September 7, 2025

by myneuronews September 7, 2025

Background and Objectives The relationship between nutrition and cognitive health has garnered increasing attention in …

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Dementia
Chronic Pain in Parkinson’s Disease: Prevalence, Sex Differences, Regional Anatomy and Comorbidities

by myneuronews September 3, 2025

by myneuronews September 3, 2025

Chronic Pain Overview Chronic pain is a complex and multifaceted condition that persists over an …

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Dementia
Emerging Role of Oligodendrocytes Malfunction in the Progression of Alzheimer’s Disease

by myneuronews August 31, 2025

by myneuronews August 31, 2025

Oligodendrocyte Function and Alzheimer’s Disease Oligodendrocytes are specialized glial cells in the central nervous system, …

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Patient-reported preferences for sleep apnoea treatments in an Australian community sample
Study Overview The research aimed to explore the preferences of individuals diagnosed with sleep apnoea…
Long-term dementia risk following electroconvulsive therapy: A GRADE-assessed systematic review and meta-analysis
Study Overview Electroconvulsive therapy (ECT) has been a significant intervention in the treatment of severe…
Association Between Intraindividual Variability in Cognitive Performance and White Matter Organisation in Chronic Mild Traumatic Brain Injury
Study Overview This research delves into the relationship between cognitive performance variability and white matter…
Longitudinal gait changes in functional neurological disorder: A 12-month prospective study
Understanding Functional Neurological Disorder Functional Neurological Disorder (FND) presents a complex challenge for both patients…
SaVeBRAIN.Kids-study protocol for a cluster-randomized stepped-wedge trial to reduce hospitalizations for mild traumatic brain injury in children in Germany
Study Overview The SaVeBRAIN.Kids initiative is a comprehensive research project focused on addressing the significant…

Mild traumatic brain injury and concussion and persisting post-concussion symptoms: new guidelines to support evidence-based assessment and management in Australia and Aotearoa New Zealand
No abstract
Association Between Intraindividual Variability in Cognitive Performance and White Matter Organisation in Chronic Mild Traumatic Brain Injury
Mild traumatic brain injury (mTBI) can result in persistent cognitive deficits (particularly in attention, processing speed, and working memory), even years after the injury. The majority of behavioural studies have focussed on averaged cognitive performance scores, such as average reaction time or accuracy scores after mTBI. However, less is understood about how mTBI affects intraindividual […]
SaVeBRAIN.Kids-study protocol for a cluster-randomized stepped-wedge trial to reduce hospitalizations for mild traumatic brain injury in children in Germany
BACKGROUND: Traumatic brain injury (TBI) is one of the most important pediatric conditions worldwide. In Germany, hospitalization rates for mild TBI drastically exceed hospitalization rates from similar healthcare systems.
A Modified Repetitive Closed Head Injury Model Inducing Persistent Neuroinflammation and Functional Deficits Without Extensive Cortical Tissue Destruction
Traumatic brain injury (TBI) remains a significant clinical challenge, with limited treatment options and long-term neurological impairments. Mild to moderate TBI represents the most common form, making it a critical therapeutic target. However, current animal models poorly reflect human TBI pathophysiology, necessitating improved preclinical paradigms. Here, we present a refined repetitive closed head injury (rCHI) […]
Traumatic Microbleeds in Mild Traumatic Brain Injury: Stability, Distribution, and Association with Other Injuries
This study aimed to investigate whether the amount of traumatic microbleeds (TMBs) detected on magnetic resonance imaging (MRI) changes in different brain regions after a 3-month follow-up in adult patients with mild traumatic brain injury (mTBI). A 3 T MRI of the brain was conducted at baseline (3-17 days after trauma) and at 3 months […]