Pro-repair properties of a human embryonic stem cell-derived astrocyte cell therapy in demyelinating disorders
Study Overview The research centers on the use of astrocytes derived from human embryonic stem cells (hESCs) as a potential […]
Channel Dysfunction as the Basis for Comorbidities in Multiple Sclerosis and Depression
Channel Dysregulation in Multiple Sclerosis In Multiple Sclerosis (MS), a complex neurological disorder characterized by the degeneration of myelin in
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The role of persistent inflammation in failed recovery after perinatal brain injury: is resolution the cure?
Persistent Inflammation and Recovery Persistent inflammation plays a crucial role in post-injury recovery, particularly following perinatal brain injuries. After such
Fasciola hepatica excretory-secretory products attenuate demyelination and reduce neuroinflammation in the Cuprizone -induced multiple sclerosis model
Study Overview This investigation centers on the impact of excretory-secretory products (ESPs) from Fasciola hepatica, a parasitic flatworm, on neuroinflammation
Autoimmune nodopathy associated with contactin-2 antibodies manifesting as Guillain-Barré syndrome: a case report
Study Overview The investigation focuses on a rare neurological condition, Guillain-Barré syndrome (GBS), which is an autoimmune disorder characterized by
Astrocytic connexin43 phosphorylation contributes to seizure susceptibility after mild traumatic brain injury
Study Overview The research investigates the role of connexin43, a key protein found in astrocytes (a type of glial cell
Ferroptosis: A potential mechanistic link to neuronal death and demyelination in MS-related depression
Ferroptosis Mechanism in Neuronal Death Ferroptosis is a form of regulated cell death characterized by the accumulation of lipid peroxides
Ferroptosis: A potential mechanistic link to neuronal death and demyelination in MS-related depression
Ferroptosis Mechanism in Neuronal Death Ferroptosis is a form of programmed cell death that is distinct from apoptosis and necrosis,
Mechanobiology of Myelin Generation/Regeneration in Health and Disease
Mechanobiological Mechanisms in Myelin Formation The formation of myelin, the protective sheath surrounding nerve fibers, is an intricate process influenced
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Stem cell-derived extracellular vesicles as immunomodulatory agents: targeting pathological crosstalk in systemic lupus erythematosus and multiple sclerosis
Pathophysiology of Systemic Lupus Erythematosus and Multiple Sclerosis Systemic lupus erythematosus (SLE) and multiple sclerosis (MS) are both chronic autoimmune