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neurons

Traumatic brain injury
Cannabidiol inhibits neuronal endoplasmic reticulum stress and apoptosis in rats with multiple concussions by regulating the PERK-eIF2alpha-ATF4-CHOP pathway

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Neuronal Endoplasmic Reticulum Stress and Apoptosis The endoplasmic reticulum (ER) plays a crucial role in …

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Traumatic brain injury
Postmortem tau in the CA2 region of the hippocampus in older adult men who participated in youth amateur American-style football

by myneuronews June 26, 2025

by myneuronews June 26, 2025

Study Overview The research focuses on examining the accumulation of tau protein in the CA2 …

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Traumatic brain injury
Budget Impact Analysis of the Use of Specific Biomarkers GFAP and UCH-L1 in the Management of Mild Traumatic Brain Injury in Spain

by myneuronews June 26, 2025

by myneuronews June 26, 2025

Background on Mild Traumatic Brain Injury Mild Traumatic Brain Injury (mTBI) is a significant public …

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Traumatic brain injury
Assessment of White Matter Changes Using Quantitative T1rho Mapping in an Open-Field Low-Intensity Blast Mouse Model of Mild Traumatic Brain Injury (mTBI)

by myneuronews June 26, 2025

by myneuronews June 26, 2025

Study Overview The study investigates the impact of mild traumatic brain injury (mTBI) on white …

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Traumatic brain injury
Mechanisms Underlying Hyperexcitability: Combining Mossy Fiber Sprouting and Mossy Cell Loss in Neural Network Model of the Dentate Gyrus

by myneuronews June 26, 2025

by myneuronews June 26, 2025

Neurobiological Mechanisms The mechanisms contributing to hyperexcitability in the dentate gyrus—a vital component of the …

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Traumatic brain injury
Outcomes of recombinant growth hormone therapy in the traumatic brain injury population: A scoping review

by myneuronews June 20, 2025

by myneuronews June 20, 2025

Study Overview The examination of the effects of recombinant growth hormone therapy on individuals suffering …

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Traumatic brain injury
Advances in Circulating Biomarkers for Neurodegenerative Diseases, Traumatic Brain Injuries, and Central Nervous System Tumors

by myneuronews June 18, 2025

by myneuronews June 18, 2025

Advancements in Biomarker Discovery Significant progress has been made in the realm of biomarker discovery, …

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Dementia
Retinal degeneration as an initial manifestation in a patient with neuronal intranuclear inclusion disease

by myneuronews June 14, 2025

by myneuronews June 14, 2025

Background of Retinal Degeneration Retinal degeneration encompasses a range of conditions characterized by the progressive …

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Traumatic brain injury
Widespread and cell-type-specific transcriptomic reorganization following mild traumatic brain injury

by myneuronews June 6, 2025

by myneuronews June 6, 2025

Transcriptomic Changes Induced by Injury Mild traumatic brain injury (mTBI) triggers significant changes in the …

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Traumatic brain injury
Single-nucleus and spatial signatures of the brainstem in normal brain and mild traumatic brain injury in male mice

by myneuronews May 31, 2025

by myneuronews May 31, 2025

Study Overview This investigation delves into the complexities of brainstem alterations in male mice, specifically …

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Brain and circulating EV proteome signatures in schizophrenia as prognostic markers for age-related dementia
Prognostic Value of EV Proteome in Schizophrenia The examination of extracellular vesicles (EVs) in schizophrenia…
Are symptoms clustered into latent classes in pediatric functional neurological disorder?
Symptoms Clustering in Pediatric Functional Neurological Disorder Pediatric functional neurological disorder (FND) presents a complex…
An e-Delphi approach to develop a patient-reported outcome measure to assess functional/dissociative seizures severity
Study Overview In recent years, the growing recognition of the impact of functional/dissociative seizures on…
Diagnostic challenges in Burkitt’s lymphoma with skull base and paravertebral involvement, and hearing loss: a case report
Study Overview This case report focuses on Burkitt’s lymphoma, a highly aggressive type of non-Hodgkin…
miR-26b-5p responds to aerobic exercise intervention for concussion recovery in adolescent athletes: a pilot trial
Study Overview The research aimed to investigate the role of miR-26b-5p in the recovery of…

Differences in symptom duration and return to sport following sport-related concussion between French-speaking Canadian and European athletes
CONCLUSION: SRC recovery times differ significantly by geography and sex in French-speaking athletes. European athletes and males report shorter symptom and RTS durations.
Using Cervical Spine Proprioception and Vestibular/Oculomotor Assessments to Identify Return-to-Play Clearance Prognosis After Adolescent Concussion
CONCLUSIONS: Cervical spine proprioception and vestibular/oculomotor symptom provocation evaluated within 3 weeks of injury were not associated with RTP clearance time, potentially reflecting the complexity and multifaceted nature of RTP decisions.
Leveraging the Enhanced Sports as a Laboratory Assessment Model to Cross-Validate a Formula Used to Predict Clinical Recovery From Concussion in Collegiate Athletes
CONCLUSIONS: Upon cross-validation, our prognostic formula had limited sensitivity and specificity when predicting clinical recovery after concussion. This formula may be used, with caution, when accompanied by a multidimensional assessment to inform clinical decision making after concussion.
Hyperphosphorylated tau and amyloid-beta proteinopathy in people over age 50: Findings from the Lieber Institute for Brain Development Brain Donation Repository
BackgroundThe Lieber Institute for Brain Development (LIBD) has one of the largest postmortem human brain banks for the study of neuropsychiatric disorders in the world. The postmortem evaluation involves neuropathological assessment for age-related protein accumulations, specifically phosphorylated tau (p-tau) and amyloid-β (Aβ).ObjectivePresent the LIBD semiquantitative assessment methodology for p-tau and Aβ by comparing proteinopathy by […]
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This case report describes the clinical response and safety of intranasal esketamine (Spravato®) in a 61-year-old female with treatment-resistant depression (TRD), a history of electroconvulsive therapy (ECT) poor response, and structural brain abnormalities secondary to left frontal lobe tissue loss from traumatic brain injury in 2008. Despite multiple antidepressant trials, atypical antipsychotic augmentation, and 6 […]