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neurons

Traumatic brain injury
Integrative Constraint-Based Modeling and Proteomics Uncover Astrocytic Metabolic Adaptations to the Post-TBI Microenvironment

by myneuronews July 12, 2025

by myneuronews July 12, 2025

Study Overview The research explores the metabolic responses of astrocytes, a type of glial cell …

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Traumatic brain injury
A one year longitudinal study of cortical myelination changes following pediatric mild traumatic brain injury

by myneuronews July 12, 2025

by myneuronews July 12, 2025

Cortical Myelination Changes Cortical myelination refers to the formation and maturation of myelin sheaths around …

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Dementia
Metabolic changes in the one-carbon metabolism-related amino acids during etoposide-induced cellular senescence of neuronal cells

by myneuronews July 3, 2025

by myneuronews July 3, 2025

Metabolic Alterations in Neuronal Cells Metabolic changes in neuronal cells, particularly during cellular senescence, play …

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Traumatic brain injury
Advancing next-generation brain organoid platforms for investigating traumatic brain injury from repeated blast exposures

by myneuronews July 3, 2025

by myneuronews July 3, 2025

Study Overview The research investigates the utilization of advanced brain organoid platforms to explore the …

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Traumatic brain injury
Biomarker evidence of neurodegeneration in mid-life former rugby players

by myneuronews July 2, 2025

by myneuronews July 2, 2025

Neurodegeneration Biomarkers Biomarkers indicative of neurodegeneration are crucial for understanding the underlying processes affecting brain …

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Traumatic brain injury
Dietary Intake of n-3 Polyunsaturated Fatty Acids Prior to a Mild Traumatic Brain Injury Demonstrates a Dose-Response Effect for Neuroprotective Benefits in Male C57BL/6 Mice

by myneuronews June 30, 2025

by myneuronews June 30, 2025

Study Overview The research investigated the relationship between dietary intake of n-3 polyunsaturated fatty acids …

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Headaches
Gepants in Primary Care: A Targeted Approach to Acute and Preventive Treatment of Migraine

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Gepants Mechanism of Action Gepants are a novel class of oral medications specifically designed to …

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Traumatic brain injury
Cannabidiol inhibits neuronal endoplasmic reticulum stress and apoptosis in rats with multiple concussions by regulating the PERK-eIF2alpha-ATF4-CHOP pathway

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Study Overview The research investigates the impact of cannabidiol (CBD) on rats subjected to multiple …

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Traumatic brain injury
Cannabidiol inhibits neuronal endoplasmic reticulum stress and apoptosis in rats with multiple concussions by regulating the PERK-eIF2alpha-ATF4-CHOP pathway

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Neuronal Endoplasmic Reticulum Stress and Apoptosis The endoplasmic reticulum (ER) plays a crucial role in …

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Traumatic brain injury
Postmortem tau in the CA2 region of the hippocampus in older adult men who participated in youth amateur American-style football

by myneuronews June 26, 2025

by myneuronews June 26, 2025

Study Overview The research focuses on examining the accumulation of tau protein in the CA2 …

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Benchmarking mobilization practice and functional outcomes in traumatic brain injury patients admitted to the intensive care unit: a three-year service evaluation
CONCLUSION: Acute TBI patients admitted to the ICU at our institution had low rates of mobilization and achieved low levels of mobility at ICU discharge. This service evaluation highlights the need for prospective studies into early mobilization practices in the neurotrauma ICU.
Cognitive and neurobehavioral phenotypes of post 9/11 veterans with epilepsy and mild traumatic brain injury
INTRODUCTION: Traumatic brain injury (TBI) and epilepsy are significant health concerns among the veteran population, but the links between mild TBI and cognitive and behavioral changes in epilepsy have been little explored. This study leveraged natural language processing of medical records and chart review to assess the prevalence and patterns of cognitive and behavioral symptoms […]
Resting-state EEG and machine learning to investigate cortical connectivity as a biomarker in chronic mTBI
INTRODUCTION: Mild traumatic brain injury (mTBI) is a heterogeneous condition with long-term sequelae, yet diagnosis in the chronic stage remains limited by reliance on acute criteria and subjective reports. Objective biomarkers are needed, as current blood-based markers show diagnostic value primarily in the acute and subacute phases. Resting-state EEG (RS-EEG) can capture large-scale network disruptions […]
Family functioning and caring for a child with acquired brain injury: a systematic review and thematic analysis
CONCLUSIONS: Family functioning after pABI can only be fully understood if multiple interconnected psychosocial and practical aspects are considered. Most included studies were of low-to-moderate quality, limiting the reliability, validity, and generalizability of the findings. Nonetheless, the conceptual model could provide a framework for understanding family functioning and enhancing outcomes for pABI.
Associations of smoking, infections, early-life exposures, and concussion with progressive-onset versus relapse-onset multiple sclerosis: A case-control study
CONCLUSIONS: PPMS shares some common risk factors with RMS, such as tobacco smoking and infectious mononucleosis, with similar effect sizes. This suggests PPMS and RMS may share underlying disease mechanisms. Further studies are needed to validate the role of other factors associated with PPMS onset.