Tag:

neuroplasticity

Functional neurological disorders
Psilocybin-Assisted Physiotherapy for Refractory Motor Functional Neurological Disorder: Protocol for a Randomised Dose-Comparison Pilot Study

by myneuronews November 4, 2025

by myneuronews November 4, 2025

Protocol Overview The study is designed as a randomized, double-blind, placebo-controlled pilot trial aimed at …

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Functional neurological disorders
Psilocybin-Assisted Physiotherapy for Refractory Motor Functional Neurological Disorder: Protocol for a Randomised Dose-Comparison Pilot Study

by myneuronews November 4, 2025

by myneuronews November 4, 2025

Study Rationale The investigation into the therapeutic potential of psilocybin for treating refractory motor functional …

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Traumatic brain injury
Association Between Intraindividual Variability in Cognitive Performance and White Matter Organisation in Chronic Mild Traumatic Brain Injury

by myneuronews November 1, 2025

by myneuronews November 1, 2025

Study Overview This research delves into the relationship between cognitive performance variability and white matter …

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Traumatic brain injury
A Modified Repetitive Closed Head Injury Model Inducing Persistent Neuroinflammation and Functional Deficits Without Extensive Cortical Tissue Destruction

by myneuronews October 31, 2025

by myneuronews October 31, 2025

Study Overview This research explores the effects of repeated mild traumatic brain injuries (mTBIs) on …

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Traumatic brain injury
Relationship Between Exercise Tolerance and Event-Related Potentials on Recovery in Adults with Postconcussion Syndrome

by myneuronews October 30, 2025

by myneuronews October 30, 2025

Study Overview This study investigates the intricate relationship between exercise tolerance and event-related potentials (ERPs) …

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Traumatic brain injury
Evolution of Axonal Injury in the Closed Head Impact Model of Engineered Rotational Acceleration in Adult Ferrets

by myneuronews October 30, 2025

by myneuronews October 30, 2025

Study Overview This research examines the impact of engineered rotational acceleration on axonal injury in …

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Functional neurological disorders
Possible bimodality in the age distribution of pediatric functional neurological disorder

by myneuronews October 25, 2025

by myneuronews October 25, 2025

Age Distribution Analysis Recent investigations into the age distribution of pediatric functional neurological disorder (FND) …

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Traumatic brain injury
The Effect of Mucuna pruriens on Depression-like Behavior Induced by a Mild Traumatic Brain Injury in Rats Is Associated with a Decrease in Brain Nitrite and Nitrate Levels

by myneuronews October 24, 2025

by myneuronews October 24, 2025

Study Overview The research investigates the impact of Mucuna pruriens, a tropical legume known for …

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Traumatic brain injury
Advancements in neurosurgical techniques for managing sports-related traumatic brain injuries

by myneuronews October 22, 2025

by myneuronews October 22, 2025

Neurosurgical Innovations In recent years, significant strides have been made in neurosurgical techniques aimed at …

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Functional neurological disorders
Revisiting motor inhibition in individuals with functional paralysis and spinal cord injury

by myneuronews October 20, 2025

by myneuronews October 20, 2025

Understanding Motor Inhibition Motor inhibition is a complex and essential neurological process that allows for …

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Macrophages and iNOS contribute to the effects of dural prolactin and repeated stress in mouse migraine models
Study Overview The investigation into the interplay between macrophages, inducible nitric oxide synthase (iNOS), and…
The biomarker and clinical changes across the Alzheimer’s continuum study (BCAS): rationale, design, and baseline characteristics of the first 1,013 participants
Study Overview The BCAS study focuses on understanding the progression of Alzheimer’s disease through a…
Women’s Issues and Female-specific Factors in Functional Neurological Disorder
Women’s Unique Experiences in FND Women facing Functional Neurological Disorder (FND) often encounter a unique…
Sex differences in the clinical characteristics of South African patients with functional seizures in a public and a private hospital
Sex Differences in Functional Seizures Research has increasingly highlighted the importance of sex differences in…
Developing Topics
Topic Identification In the early stages of research, selecting a compelling and relevant topic is…

Basic Science and Pathogenesis
CONCLUSION: These data identify sex differences in the extent of axonal pathologies in brain white matter acutely after TBI, which appears related to sex differences in axon diameter. Notably, these findings further shed light on insights that damaged and degenerating axons following TBI may provide a rich source of APP/Aβ as pathologic substrate contributing to […]
Basic Science and Pathogenesis
CONCLUSION: Young amateur contact sports players are at risk for structural and microstructural brain injuries, including enlarged ventricles, cavum septum pellucidum, microvascular injury, blood-brain barrier breach, interface astrocytosis, and glymphatic remodeling. Future studies are needed to clarify the association between these early structural injuries after RHI and risk for CTE.
The relationship between dispositional mindfulness and psychological, cognitive, and functional outcomes following mild traumatic brain injury
Background: Most individuals who sustain a mild uncomplicated Traumatic Brain Injury (mTBI) recover within 1-3 months. However, a significant proportion consistently report ongoing cognitive, psychological, and somatic sequelae, which can be functionally disabling and hinder active participation in society following injury. The present study examined dispositional mindfulness as a targetable protective factor as it pertains […]
Interaction of Obese Body Mass Index and Comorbidities on Inflammatory Profiles and Clinical Outcomes After Traumatic Brain Injury: A TRACK-TBI Study
CONCLUSIONS: Obesity and comorbidity profiles are associated with an inflammatory response with the potential to impact recovery; consideration of systemic health at the time of injury could improve recovery.
Multimodal Canonical Correlation Analysis with Joint Independent Component Analysis (mCCA+jICA) of IVIM and ASL MRI Reveals Perfusion and Diffusion Abnormalities in mTBI-A Pilot Study
Mild traumatic brain injury (mTBI) frequently causes subtle brain changes that are difficult to detect with conventional diagnostic approaches. In this exploratory pilot study, we combined tri-exponential intravoxel incoherent motion (IVIM) and pseudocontinuous arterial spin labeling (pCASL) MRI with Multimodal Canonical Correlation Analysis and joint independent component analysis (mCCA+jICA) to identify imaging signatures distinguishing mTBI […]