Tag:

neuroscience

Functional neurological disorders
Penetrance of neurodevelopmental copy number variants is associated with variations in cortical morphology

by myneuronews May 25, 2025

by myneuronews May 25, 2025

Neurodevelopmental Variants and Penetrance Neurodevelopmental copy number variants (CNVs) represent significant alterations in an individual’s …

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Functional neurological disorders
A narrative literature review of white matter microstructure in individuals at clinical high risk for psychosis

by myneuronews May 23, 2025

by myneuronews May 23, 2025

White Matter Microstructure in Psychosis White matter, the tissue in the brain that consists of …

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Functional neurological disorders
Rhythm training improves word-reading in children with dyslexia

by myneuronews May 21, 2025

by myneuronews May 21, 2025

Impact of Rhythm Training on Dyslexia The research indicating that rhythm training can significantly improve …

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Functional neurological disorders
Functional neurological disorder: Practical management

by myneuronews May 21, 2025

by myneuronews May 21, 2025

Understanding Functional Neurological Disorder Functional Neurological Disorder (FND) represents a complex interplay between neurological and …

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Functional neurological disorders
Atypical cadherin FAT2 is required for synaptic integrity and motor behaviors

by myneuronews May 20, 2025

by myneuronews May 20, 2025

Role of fat2 in Synaptic Integrity The study of the atypical cadherin FAT2 unveils its …

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Traumatic brain injury
Predictors of skull fracture and intracerebral pathology after pediatric traumatic brain injury

by myneuronews May 19, 2025

by myneuronews May 19, 2025

Predictors of Skull Fracture Pediatric traumatic brain injury (TBI) frequently involves skull fractures, which are …

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Functional neurological disorders
Role of Selective Serotonin Reuptake Inhibitors, Serotonin-Norepinephrine Reuptake Inhibitors and Psychedelics in the Treatment of Major Depressive Disorder: A Perspective on Mechanistic Insight and Current Status

by myneuronews May 19, 2025

by myneuronews May 19, 2025

Current Pharmacological Approaches in Depression Treatment In recent years, the treatment landscape for Major Depressive …

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Functional neurological disorders
Research Progress on BDNF and Depression

by myneuronews May 13, 2025

by myneuronews May 13, 2025

Understanding BDNF’s Role in Depression Brain-derived neurotrophic factor (BDNF) is a protein that plays a …

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Functional neurological disorders
Automated seizure detection in epilepsy using a novel dynamic temporal-spatial graph attention network

by myneuronews May 12, 2025

by myneuronews May 12, 2025

Methodology and Model Architecture The study introduces a sophisticated machine learning approach aimed at enhancing …

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Functional neurological disorders
Feasibility of direct-to-home teleneuropsychological evaluations in U.S. Veterans with functional seizures

by myneuronews May 12, 2025

by myneuronews May 12, 2025

Feasibility of Teleneuropsychological Evaluations The study of direct-to-home teleneuropsychological evaluations represents a significant advancement in …

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Real-world assessment of current migraine prophylaxis in Egypt: a multicenter national study
Study Overview The research conducted aimed to evaluate the existing practices regarding migraine prophylaxis across…
Treatment of Alzheimer’s disease from gut-brain interactions based on theory of “spleen deficiency leading to obstruction of nine orifices”
Understanding Gut-Brain Interactions The relationship between the gut and the brain is increasingly recognized as…
Update on functional vestibular and gait disorders
Current Understanding of Vestibular and Gait Disorders Vestibular and gait disorders have increasingly garnered attention…
Brain creatine concentrations are associated with sex and symptom severity after concussion: a cross-sectional MR-spectroscopy investigation of adolescents with concussion
Study Overview The investigation focused on the relationship between brain creatine concentrations and both sex…
Anti-Inflammatory Potential of Stearidonic Acid Ethanolamide in a Model of Mild Traumatic Brain Injury in Mice
Study Overview This study investigates the effects of stearidonic acid ethanolamide (SDA-EA) on inflammation following…

Incretin Mimetics as Potential Therapeutics for Concussion and Traumatic Brain Injury: A Narrative Review
Traumatic brain injury (TBI) represents a significant health concern, with an estimated 70 million annual cases worldwide. Mild brain trauma (concussions) is the most common TBI (81%), followed by moderate (11%) and severe (8%). Cytokine release and neuroinflammation after TBI may cause blood-brain barrier and tissue damage, triggering unfavorable outcomes, including disabilities and mortality. Current […]
N-Stearidonoylethanolamine Restores CA1 Synaptic Integrity and Reduces Astrocytic Reactivity After Mild Traumatic Brain Injury
Mild traumatic brain injury (mTBI) disrupts hippocampal network function through coordinated alterations in glial reactivity, synaptic integrity, and adult neurogenesis. Effective therapeutic approaches targeting these interconnected processes remain limited. Lipid-derived molecules capable of modulating these mTBI-induced disturbances are emerging as promising neuroprotective candidates. Here, we investigated the effects of N-stearidonylethanolamine (SDEA), an ω-3 ethanolamide, in […]
Relationship between illness perceptions, coping style and post-concussion symptoms after systemic traumatic injury: A comparison of those with and without mild traumatic brain injury
Research has reported variable findings when investigating the relationship between outcome and coping style and illness perceptions after mild traumatic brain injury (mTBI). The present study investigated 138 individuals who had been admitted to hospital after suffering a traumatic systemic injury, with 91 of these individuals also fulfilling criteria for mTBI and 47 comprising a […]
Injury-induced CTE-like pathology emerges in a human multicellular in vitro brain model and reveals mitochondrial and neurovascular regulation
Chronic traumatic encephalopathy (CTE) is a progressive neurodegenerative disease linked to repetitive mild head impacts, but no human-based experimental system exists to study injury-induced CTE-like pathology. Here, we establish a long-lived, human multicellular in vitro brain platform in which controlled mechanical injury induces key cellular features of CTE-like pathology. Injured cultures developed persistent tau phosphorylation, […]
Explosive shock wave exposure leads to age-accelerated motor and sensory decline in C. elegans
CONCLUSIONS: Defined shock wave exposure is sufficient to provoke long-term neuronal functional decline in C. elegans , accompanied by structural deterioration and premature neurodegeneration. This tractable model enables lifelong phenotyping and mechanistic dissection of how an acute shock wave insult progresses to chronic neuronal dysfunction, and provides a scalable platform for identifying molecular and pharmacological […]