Tag:

neuroscience

Headaches
Changes in metabolite profiles in the cerebrospinal fluid and in human neuronal cells upon tick-borne encephalitis virus infection

by myneuronews June 14, 2025

by myneuronews June 14, 2025

Metabolite Profile Changes Upon infection with the tick-borne encephalitis virus (TBEV), significant alterations occur in …

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Functional neurological disorders
Connectogram-COH: A Coherence-Based Time-Graph Representation for EEG-Based Alzheimer’s Disease Detection

by myneuronews June 13, 2025

by myneuronews June 13, 2025

Coherence-Based Time-Graph Methodology The study employs a coherence-based time-graph methodology to create a novel representation …

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Functional neurological disorders
Altered self-processing brain networks in paediatric functional neurological disorder

by myneuronews June 12, 2025

by myneuronews June 12, 2025

Altered Self-Processing Mechanisms Investigating the intricate world of how our brains perceive the self provides …

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Traumatic brain injury
Virtual reality-based eye tracking throughout typical concussion recovery

by myneuronews June 10, 2025

by myneuronews June 10, 2025

Virtual Reality Eye Tracking Technology Virtual reality (VR) eye tracking technology represents a significant advancement …

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Dementia
One size does not fit all: how type of menopause and hormone therapy matters for brain health

by myneuronews June 9, 2025

by myneuronews June 9, 2025

Menopause Types and Their Impact Menopause is a significant transition in a woman’s life, marked …

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Functional neurological disorders
Concentration-dependent structural transition of huntingtin protein in Huntington’s disease

by myneuronews June 7, 2025

by myneuronews June 7, 2025

Concentration-Dependent Effects on Huntingtin Structure Recent studies have revealed that the huntingtin protein, associated with …

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Functional neurological disorders
Development and in vitro characterization of humanized antibodies for blocking human TRPM4 channel

by myneuronews June 5, 2025

by myneuronews June 5, 2025

Background on TRPM4 Channel The TRPM4 channel, a member of the transient receptor potential (TRP) …

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Functional neurological disorders
Development and in vitro characterization of humanized antibodies for blocking human TRPM4 channel

by myneuronews June 5, 2025

by myneuronews June 5, 2025

Development of Humanized Antibodies The study focuses on the creation of humanized antibodies targeting the …

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Functional neurological disorders
Dynamic nanodomains dictate macroscopic properties in lead halide perovskites

by myneuronews June 2, 2025

by myneuronews June 2, 2025

Dynamic Nanodomain Behavior The study of dynamic nanodomains in lead halide perovskites reveals a fascinating …

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Functional neurological disorders
Loss of CD98HC phosphorylation by ATM impairs antiporter trafficking and drives glutamate toxicity in Ataxia telangiectasia

by myneuronews June 2, 2025

by myneuronews June 2, 2025

Loss of CD98HC Phosphorylation and Its Effects The research highlights the critical role of CD98HC, …

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The Diagnostic and Prognostic Role of Biomarkers in Mild Traumatic Brain Injury: An Umbrella Meta-Analysis
CONCLUSIONS: The findings underscore the clinical promise of fluid biomarkers in the management of mTBI. S100B and GFAP are particularly valuable as screening and confirmatory markers, respectively. Nonetheless, further standardization of biomarker thresholds and additional longitudinal studies are necessary to validate the roles of UCH-L1, NfL, and Tau protein. The integration of these biomarkers into […]
Exo70 Protects Against Memory and Synaptic Impairments Following Mild Traumatic Brain Injury
Mild traumatic brain injury (mTBI), a leading cause of disability in young adults, often results from external forces that damage the brain. Cellularly, mTBI induces oxidative stress, characterized by excessive reactive oxygen species (ROS) and diminished antioxidant capacity. This redox imbalance disrupts hippocampal glutamatergic transmission and synaptic plasticity, where NMDA receptors (NMDARs) are crucial. The […]
Neurobiology of Chronic Pain, Posttraumatic Stress Disorder, and Mild Traumatic Brain Injury
CONCLUSIONS: Common therapeutic processes, such as focusing on sensitization, might be helpful for these conditions. As for causal mechanisms related to sensitization in the causality of psychological injuries, the major ones hypothesized relate to the biopsychosocial model, psychological control, and activation-inhibition coordination.
Neurocognitive Outcomes After Extracranial Surgery and General Anesthesia in Patients with a History of Mild-to-Moderate Traumatic Brain Injury: Systemic Review and Meta-Analysis
Accelerated neurocognitive decline associated with surgeries under general anesthesia (GA), a phenomenon referred to as postoperative neurocognitive disorder (PND), is a significant public health concern. It not only poses inherent risks but may also contribute to the development of other neurodegenerative disorders. We systematically searched five databases for studies examining cognitive function in patients with […]
Assessment of White Matter Changes Using Quantitative T1rho Mapping in an Open-Field Low-Intensity Blast Mouse Model of Mild Traumatic Brain Injury (mTBI)
Blast-induced mild traumatic brain injury (mTBI) occurs when shock waves travel through blood vessels and cerebrospinal fluid, leading to cerebral demyelination, which results in cognitive impairments and neuropsychiatric issues that impact quality of life. This study aims to evaluate myelin changes in white matter in mice with mTBI induced by an open-field low-intensity blast (LIB) […]