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NfL

Functional neurological disorders
Advances in Diagnostic Approaches for Alzheimer’s Disease: From Biomarkers to Deep Learning Technology

by myneuronews May 30, 2025

by myneuronews May 30, 2025

Advancements in Biomarker Identification Recent developments in the field of Alzheimer’s disease diagnostics have centered …

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Traumatic brain injury
Impact of prior exposures on biomarkers of blast during military tactical training

by myneuronews May 28, 2025

by myneuronews May 28, 2025

Study Overview This investigation aims to examine how prior exposures, particularly to blast injuries, influence …

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Traumatic brain injury
A new characterisation of acute traumatic brain injury: the NIH-NINDS TBI Classification and Nomenclature Initiative

by myneuronews May 23, 2025

by myneuronews May 23, 2025

Definition and Classification of TBI Traumatic brain injury (TBI) is a complex and multifaceted condition …

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Functional neurological disorders
Fluid Biomarkers in Demyelinating Spectrum Disorders: Past, Present, and Prospects

by myneuronews May 14, 2025

by myneuronews May 14, 2025

Fluid Biomarker Applications in Demyelinating Disorders Fluid biomarkers play a crucial role in the diagnosis …

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Biomarkers Traumatic brain injury
Exploring the Role of Salivary Biomarkers in Mild Traumatic Brain Injury Diagnosis

by Ioannis Mavroudis November 16, 2024

by Ioannis Mavroudis November 16, 2024

Abstract: Mild Traumatic Brain Injury (mTBI) is a significant public health concern, with its diagnosis …

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Midlife plasma proteomic profiles indicate altered amyloid and tau processing in former elite rugby players
CONCLUSIONS: Ex-players showed distinctive plasma biomarker changes, more prominently in ex-forwards, possibly reflecting greater RHI exposure. Plasma KLK6, an endothelial serine protease, was reduced across the ex-player group, with potential diagnostic or prognostic utility in future. Reduced GFAP and SNAP25 in ex-forwards has an uncertain basis, while elevated p-tau-(181) more so than p-tau(217) points towards […]
A Guide to the Interpretation and Reliability of Annual Collegiate ImPACT Baselines by Sex
CONCLUSIONS: This study found sex differences on ImPACT performance, suggesting that sex-specific MDC values are needed to evaluate significant changes in ImPACT scores. Additionally, this study found several ImPACT subtest scores to be unreliable, suggesting only moderate to good scores be used in clinical evaluation.
<em>Taking Control of Your Functional Cognitive Symptoms: Workbook</em>-A Novel Intervention
CONCLUSIONS: This promising new multimodality behavioral health intervention can be considered to be in stage 1 (i.e., intervention generation, refinement, modification, adaptation, and pilot testing). Further pilot testing is being conducted and will need to be followed by traditional efficacy testing (in stage 2).
Hemodynamic Oscillations in Mild TBI During Postural Change: An fNIRS Pilot Study
We demonstrate that low-frequency oscillations (LFOs) in cerebral hemodynamics, measured by frequency-domain functional near-infrared spectroscopy (FD-fNIRS), reflect altered cerebral hemodynamic oscillations in mild traumatic brain injury (mTBI). In a pilot study of two mTBI and 13 healthy subjects undergoing head-of-bed positional changes, we analyzed total hemoglobin concentration (THC), oxyhemoglobin (HbO), and deoxyhemoglobin (Hb) dynamics using […]
Normative Data for Single- and Dual-Task Tandem Gait Performance in Collegiate Athletes
CONCLUSION: Our results provide robust normative data for single- and dual-task tandem gait stratified by relevant patient factors that can be immediately used by clinicians and future researchers. Future research should compare the use of individual baseline versus normative data for acute concussion tracking.

NfL

Advances in Diagnostic Approaches for Alzheimer’s Disease: From Biomarkers to Deep Learning Technology

Impact of prior exposures on biomarkers of blast during military tactical training

A new characterisation of acute traumatic brain injury: the NIH-NINDS TBI Classification and Nomenclature Initiative

Fluid Biomarkers in Demyelinating Spectrum Disorders: Past, Present, and Prospects

Exploring the Role of Salivary Biomarkers in Mild Traumatic Brain Injury Diagnosis