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NfL

Traumatic brain injury
A new characterisation of acute traumatic brain injury: the NIH-NINDS TBI Classification and Nomenclature Initiative

by myneuronews May 23, 2025

by myneuronews May 23, 2025

Definition and Classification of TBI Traumatic brain injury (TBI) is a complex and multifaceted condition …

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Functional neurological disorders
Fluid Biomarkers in Demyelinating Spectrum Disorders: Past, Present, and Prospects

by myneuronews May 14, 2025

by myneuronews May 14, 2025

Fluid Biomarker Applications in Demyelinating Disorders Fluid biomarkers play a crucial role in the diagnosis …

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Biomarkers Traumatic brain injury
Exploring the Role of Salivary Biomarkers in Mild Traumatic Brain Injury Diagnosis

by Ioannis Mavroudis November 16, 2024

by Ioannis Mavroudis November 16, 2024

Abstract: Mild Traumatic Brain Injury (mTBI) is a significant public health concern, with its diagnosis …

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Subtype shift, relapse rate and risk factors of frequent relapse in cluster headache: A multicenter, prospective, longitudinal observation
Study Overview The study focused on understanding the various types of cluster headaches, examining the…
Quercetin as a Multi-Target Natural Therapeutic in Aging-Related Diseases: Systemic Molecular and Cellular Mechanisms
Mechanisms of Action Quercetin, a flavonoid found abundantly in many fruits, vegetables, and beverages, exhibits…
Exploring suicidal ideation and self-harm after moderate-severe traumatic brain injury within a transdiagnostic framework
Understanding Suicidal Ideation Suicidal ideation refers to the thoughts or considerations of ending one’s own…
Neurophysiology of Downhill Mountain Bike Athletes-Benchmark Assessments of Event-Related Potentials
Neurophysiological Insights The neurophysiological aspects of downhill mountain biking are critical to understanding how athletes…
A Semi-Automated and Unbiased Microglia Morphology Analysis Following Mild Traumatic Brain Injury in Rats
Study Overview This study investigates the morphological changes in microglia, the immune cells of the…

Exploring suicidal ideation and self-harm after moderate-severe traumatic brain injury within a transdiagnostic framework
More research is needed on suicidal ideation (SI) and self-harm (SH) following moderate-severe traumatic brain injury (TBI). Previous studies have shown limited, inconsistent associations with demographic and injury factors and relied on diagnosis-specific analyses of psychiatric factors. This cross-sectional survey included 387 individuals with moderate-severe TBI and examined correlations between SI, SH, and 35 other […]
Neurophysiology of Downhill Mountain Bike Athletes-Benchmark Assessments of Event-Related Potentials
Background: Downhill mountain biking (MTB) is a high-velocity sport where riders are potentially exposed to impacts and concussion. Rapidly obtained Event-Related Potentials (ERPs) are a promising use of portable electroencephalography for clinical assessment of concussion-related neurological impairment at the point of care. However, the baseline neuroelectric profile of this specific sporting population is not fully […]
A Semi-Automated and Unbiased Microglia Morphology Analysis Following Mild Traumatic Brain Injury in Rats
Mild traumatic brain injury (mTBI) affects over 40 million people every year. One of its features includes the activation of microglia, the resident immune cells of the brain. Microglia assume different morphological states depending on their level of activation, such as surveilling ramified and activated hypertrophic, ameboid, and rod-like microglia. These states can be distinguished […]
Evaluation of Traumatic Brain Injury Severity Using the Abbreviated Injury Scale and the Injury Severity Score: A Retrospective Study in Two Eastern European Centers
Introduction: Traumatic brain injury (TBI) is a significant global public health issue, with long-term impacts on patients. This study examines the relationship between TBI severity, as measured by the Abbreviated Injury Scale (AIS) and the Injury Severity Score (ISS) at admission, and various sociodemographic, clinical, and injury-related factors. Methods: We conducted a retrospective analysis using […]
Non-invasive vagus nerve stimulation is associated with the reduction in persistent post-concussion symptoms: an observational study
INTRODUCTION: Traumatic brain injury (TBI) remains a major public health challenge, with mild TBI (mTBI) frequently resulting in persistent cognitive, affective, and somatic symptoms. Non-invasive vagus nerve stimulation (nVNS) has demonstrated potential in reducing neuroinflammation and promoting recovery in preclinical TBI models. This retrospective, observational study assessed the impact of adjunctive nVNS on postconcussive symptoms […]

NfL

A new characterisation of acute traumatic brain injury: the NIH-NINDS TBI Classification and Nomenclature Initiative

Fluid Biomarkers in Demyelinating Spectrum Disorders: Past, Present, and Prospects

Exploring the Role of Salivary Biomarkers in Mild Traumatic Brain Injury Diagnosis