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  • Medical professionalsTraumatic brain injury

    Overview of Classification Systems and Diagnostic Criteria for Traumatic Brain Injury Syndromes

    by Ioannis Mavroudis February 13, 2024
    by Ioannis Mavroudis February 13, 2024

    This article presents a comprehensive overview of the classification systems for traumatic brain injuries (TBI) …

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  • Real-world assessment of current migraine prophylaxis in Egypt: a multicenter national study
    Study Overview The research conducted aimed to evaluate the existing practices regarding migraine prophylaxis across…
  • Treatment of Alzheimer’s disease from gut-brain interactions based on theory of “spleen deficiency leading to obstruction of nine orifices”
    Understanding Gut-Brain Interactions The relationship between the gut and the brain is increasingly recognized as…
  • Update on functional vestibular and gait disorders
    Current Understanding of Vestibular and Gait Disorders Vestibular and gait disorders have increasingly garnered attention…
  • Brain creatine concentrations are associated with sex and symptom severity after concussion: a cross-sectional MR-spectroscopy investigation of adolescents with concussion
    Study Overview The investigation focused on the relationship between brain creatine concentrations and both sex…
  • Anti-Inflammatory Potential of Stearidonic Acid Ethanolamide in a Model of Mild Traumatic Brain Injury in Mice
    Study Overview This study investigates the effects of stearidonic acid ethanolamide (SDA-EA) on inflammation following…

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  • Brain creatine concentrations are associated with sex and symptom severity after concussion: a cross-sectional MR-spectroscopy investigation of adolescents with concussion
    CONCLUSION: Post-concussion sex differences in creatine concentrations were detected, as higher creatine levels moderately correlated with patient-reported outcomes. Creatine may reflect altered energy dynamics in the brain. The absence of a non-injured control group limits determination of whether these differences are concussion-specific or reflective of baseline physiology.
  • Management of the paediatric patient with acute head trauma
    Acute head trauma (AHT) leading to traumatic brain injury is an important cause of paediatric morbidity and mortality. Injury severity depends on the mechanism of trauma and age of the child. The vast majority of childhood AHT cases are mild, require no therapy, and leave no long-term sequelae. However, it is important to identify individuals […]
  • Appropriateness of imaging requests for pediatric traumatic brain injury in the emergency department: a retrospective cross-sectional study
    CONCLUSION: A significant gap exists between clinical practice and guideline-based imaging for pediatric TBI in Chile. Reinforcing validated decision tools may help optimize imaging use and minimize unnecessary radiation exposure.
  • Anti-Inflammatory Potential of Stearidonic Acid Ethanolamide in a Model of Mild Traumatic Brain Injury in Mice
    Chronic neuroinflammation is recognized as a pivotal mechanism responsible for secondary damage following mild traumatic brain injury (mTBI), underscoring the critical need for therapeutic strategies capable of mitigating this pathological process. This study evaluated the anti-inflammatory properties of stearidonic acid ethanolamide (SDEA, C20H33NO2). The findings indicate that mTBI triggers persistent neuroinflammation, which is correlated with […]
  • Stability of salivary microRNA measures across an NCAA Division I football season: Implications for microRNA as a biomarker of concussion
    CONCLUSIONS: Our study found no significant differences in time points for target microRNA, but ICC statistics indicated low reliability across the season. These findings suggest that microRNA expression may be variable throughout the season regardless of concussive trauma, and clinicians should be aware that changes in microRNA expression should not be directly attributed to concussive […]

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