Tag:

pathophysiology

Traumatic brain injury
Post-Concussion Syndrome and Functional Neurological Disorder: Diagnostic Interfaces, Risk Mechanisms, and the Functional Overlay Model

by myneuronews July 29, 2025

by myneuronews July 29, 2025

Understanding Post-Concussion Syndrome Post-concussion syndrome (PCS) represents a complex array of symptoms that may arise …

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Functional neurological disorders
Study Protocol: Investigating the Effects of Transcranial Pulse Stimulation in Parkinson’s Disease

by myneuronews July 29, 2025

by myneuronews July 29, 2025

Background and Rationale Parkinson’s Disease (PD) is a progressive neurodegenerative disorder characterized primarily by motor …

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Functional neurological disorders
GSAformer: Group sparse attention transformer for functional brain network analysis

by myneuronews July 27, 2025

by myneuronews July 27, 2025

Methodology Overview The study introduced GSAformer, a novel model designed to improve the analysis of …

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Movement Disorders
Distinct inflammatory profiles in young-onset versus late-onset Alzheimer’s disease

by myneuronews July 25, 2025

by myneuronews July 25, 2025

Inflammatory Profiles in Alzheimer’s Disease Alzheimer’s disease (AD) is characterized by the accumulation of amyloid-beta …

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Stroke
Circulating Immune Cell Signature Analysis in HFpEF Across Species

by myneuronews July 25, 2025

by myneuronews July 25, 2025

Study Overview The investigation into circulating immune cell signatures in heart failure with preserved ejection …

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Functional neurological disorders
Polycystic ovary syndrome as a risk factor for cancer

by myneuronews July 25, 2025

by myneuronews July 25, 2025

Risk Factors Associated with Polycystic Ovary Syndrome Polycystic ovary syndrome (PCOS) is characterized by a …

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Dementia
Cortical inhibitory and facilitatory alterations in the continuum of alpha-synucleinopathies

by myneuronews July 25, 2025

by myneuronews July 25, 2025

Cortical Inhibition in Alpha-Synucleinopathies Alterations in cortical inhibition have been observed in alpha-synucleinopathies, which include …

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Functional neurological disorders
Neuroimaging correlates of genetics in patients with Wilson’s disease

by myneuronews July 24, 2025

by myneuronews July 24, 2025

Neuroimaging Findings in Wilson’s Disease Neuroimaging plays a crucial role in understanding Wilson’s disease, a …

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Functional neurological disorders
Neuroimaging correlates of genetics in patients with Wilson’s disease

by myneuronews July 24, 2025

by myneuronews July 24, 2025

Neuroimaging Findings in Wilson’s Disease Neuroimaging findings in Wilson’s disease reveal significant alterations in brain …

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Functional neurological disorders
The Frmpd3 Protein Regulates Susceptibility to Epilepsy by Combining with GRIP and GluA2

by myneuronews July 23, 2025

by myneuronews July 23, 2025

Role of Frmpd3 in Epilepsy The study presents compelling evidence that Frmpd3 plays a significant …

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Response to Training in Emotion Recognition Function for Mild TBI/PTSD Survivors: Pilot Study
CONCLUSIONS: Our data show promising clinical potential and warrant future research, given the importance of developing novel interventions to train and restore recognition of emotion in Veterans with mTBI/PTSD.
Post-Concussion Syndrome and Functional Neurological Disorder: Diagnostic Interfaces, Risk Mechanisms, and the Functional Overlay Model
CONCLUSIONS: PCS and FND/FCD should be conceptualized along a continuum of brain dysfunction, shaped by injury, psychology, and contextual factors. Early recognition of functional overlays and stratified psychological interventions may improve outcomes for patients with persistent, medically unexplained symptoms after head trauma. This review introduces the Functional Overlay Model as a novel framework to enhance […]
Neurological Disorders and Clinical Progression in Boxers from the 20th Century: A Narrative Review
Introduction: There are no validated clinical diagnostic criteria for chronic traumatic encephalopathy or traumatic encephalopathy syndrome (TES). To understand the historical clinical condition, its applicability to modern day athletes, and the pathogenesis of clinical problems, we examined the literature describing boxers from the 20th century, with specific attention paid to neurological findings and characteristics of […]
Three-Month Durability of Bilateral Two-Level Stellate Ganglion Blocks for Traumatic Brain Injury: A Retrospective Analysis
Background/Objectives: The primary aim of the study was to determine if ultrasound-guided, bilateral, two-level stellate ganglion blocks (SGBs), also known as two-level cervical sympathetic chain blocks (2LCSBs), performed on subsequent days, improve symptoms of chronic mild Traumatic Brain Injury (TBI) over a three-month period, as assessed by the Neurobehavioral Symptom Inventory (NSI). A secondary objective […]
Trends and Risk Factors for the Hospitalization of Older Adults Presenting to Emergency Departments After a Bed-Related Fall: A National Database Analysis
Background/objectives: Falls are a leading cause of traumatic injury and hospitalization for adults over the age of 65. While common, bed-related falls are relatively understudied when compared to ambulatory falls. The aim of this study is to characterize the risk factors for the hospitalization of older adults presenting to U.S. emergency departments (EDs) after a […]