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pathophysiology of FND

Functional neurological disorders
Circulating inflammatory proteins as pathogenic mediators and potential therapeutic targets in myasthenia gravis

by myneuronews June 26, 2025

by myneuronews June 26, 2025

Pathogenic Role of Inflammatory Proteins In recent studies, inflammatory proteins have emerged as key players …

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Functional neurological disorders
Photoactivatable Exosenolytics Activate Natural Killer Cells for Delaying Osteoarthritis

by myneuronews June 19, 2025

by myneuronews June 19, 2025

Mechanism of Action The study explores how photoactivatable exosenolytics function by triggering specific pathways in …

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Functional neurological disorders
RT-QuIC optimization for prion detection in soils

by myneuronews June 16, 2025

by myneuronews June 16, 2025

Optimization Strategies for RT-QuIC RT-QuIC, or Real-Time Quaking-Induced Conversion, is rapidly gaining recognition as a …

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Functional neurological disorders
Seizures and Functional Deficits across Mendelian Disorders of Epigenetic Machinery: Differential Effects as a Function of Epigenetic Modifications

by myneuronews June 13, 2025

by myneuronews June 13, 2025

Understanding Mendelian Disorders Mendelian disorders are genetic conditions resulting from mutations in a single gene …

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Functional neurological disorders
Microglia-drive IRF8 upregulates complement pathway in Parkinson’s disease

by myneuronews June 2, 2025

by myneuronews June 2, 2025

Microglia and Parkinson’s Disease Pathophysiology Microglia, the resident immune cells of the central nervous system, …

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Functional neurological disorders
Presymptomatic Biological, Structural, and Functional Diagnostic Biomarkers of Autism Spectrum Disorder

by myneuronews May 20, 2025

by myneuronews May 20, 2025

Biological Markers of Autism Spectrum Disorder Biological markers for Autism Spectrum Disorder (ASD) represent a …

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Functional neurological disorders
HSD17B1-mediated trophoblast differentiation lowers estrogen levels in early-onset preeclampsia

by myneuronews May 20, 2025

by myneuronews May 20, 2025

HSD17B1 Role in Trophoblast Differentiation The study of HSD17B1 (Hydroxysteroid Dehydrogenase Type 1) highlights its …

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Functional neurological disorders
Memory processing by hippocampal adult-born neurons

by myneuronews May 9, 2025

by myneuronews May 9, 2025

Memory Functions of Adult-Born Neurons Recent research has shed light on the remarkable role of …

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Functional neurological disorders
Hypoxic preconditioning modulates BDNF signaling to alleviate depression-like behaviors in mice and its whole transcriptome sequencing analysis

by myneuronews May 2, 2025

by myneuronews May 2, 2025

Mechanisms of Hypoxic Preconditioning Hypoxic preconditioning (HP) is an intriguing physiological process whereby exposure to …

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Functional neurological disorders
Silencer variants are key drivers of gene upregulation in Alzheimer’s disease

by myneuronews April 29, 2025

by myneuronews April 29, 2025

Silencer Variants and Gene Regulation Recent advancements in genetic research have shed light on the …

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Excessive emotional reactivity in a case of behavioral variant frontotemporal dementia with amyotrophic lateral sclerosis
Case Presentation The patient, a 60-year-old male, presented with a progressive decline in social functioning…
The effects of radiation therapy on the brain: implications for management
Effects of Radiation Therapy on Brain Function Radiation therapy, a common treatment modality for various…
A rare neurological odyssey: Gastric adenocarcinoma and leptomeningeal carcinomatosis – A Peruvian case study
Case Presentation A 56-year-old male presented to the hospital with a complex clinical history, including…
Aging With Strength: Functional Training to Support Independence and Quality of Life
Importance of Functional Training Functional training is a crucial aspect of exercise regimens, especially for…
Uncovering Putative Causal Non-Coding RNAs in Acute and Chronic Myeloid Leukemia: A Genome-Wide Mendelian Randomization Study
Study Overview The investigation aimed to explore the role of non-coding RNAs in the development…

Quantification of the cerebral pressure-flow relationship directional sensitivity: Reliability of shorter repeated squat-stand durations
The magnitude of changes in middle cerebral artery mean blood velocity (MCAv) is attenuated when mean arterial pressure (MAP) increases compared with when MAP decreases. This directional sensitivity has been characterized using a time-corrected ratio calculated on MCAv and MAP changes induced by repeated squat-stands (RSS) at 0.05 and 0.10 Hz for 300 s (∆MCAv(T)/∆MAP(T)). […]
A Comparison of Quantitative Pupillometry and VOMS in Division 1 Female Soccer Players
Background and Objectives: Vision uses about half of the pathways within the brain, and these anatomical structures are susceptible to injury in concussion. Authors have suggested that subconcussive head impacts, common in soccer, may disrupt visual function. The following study aimed to explore and compare quantitative pupillometry and Vestibular Ocular Motor Screening (VOMS) in female […]
Distinct clinical phenotypes and their neuroanatomic correlates in chronic traumatic brain injury
Accumulating evidence of heterogeneous long-term outcomes after traumatic brain injury (TBI) has challenged longstanding approaches to TBI outcome classification that are largely based on global functioning. A lack of studies with clinical and biomarker data from individuals living with chronic (>1 year post-injury) TBI has precluded refinement of long-term outcome classification ontology. Multimodal data in […]
The national football league concussion settlement race-norming incident in context
CONCLUSION: Replacing race-norms involves using performance-based estimates of preexisting skill level that are individualized and not subject to racial profiling. In research, racial/ethnic group comparisons give way to the study of measurable sociocultural dimensions on which these groupings differ that potentially impact neuropsychological test scores. To date, few such dimensions have demonstrated incremental contributions beyond […]
Acceptability of a Brain-Injury-Tailored Yoga and Meditation Program Among Female Patients with Concussion
Background: Although concussion symptoms often resolve within 4-6 weeks, for a minority of patients, persistent postconcussion symptoms (PPCS), such as headaches, fatigue, and mood disturbances, may continue for months or years following a head injury. Rehabilitation of this group-often female-is crucial for reducing health and gender disparities in concussion recovery. A recent report by the […]