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pathophysiology of FND

Functional neurological disorders
Presymptomatic Biological, Structural, and Functional Diagnostic Biomarkers of Autism Spectrum Disorder

by myneuronews May 20, 2025

by myneuronews May 20, 2025

Biological Markers of Autism Spectrum Disorder Biological markers for Autism Spectrum Disorder (ASD) represent a …

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Functional neurological disorders
HSD17B1-mediated trophoblast differentiation lowers estrogen levels in early-onset preeclampsia

by myneuronews May 20, 2025

by myneuronews May 20, 2025

HSD17B1 Role in Trophoblast Differentiation The study of HSD17B1 (Hydroxysteroid Dehydrogenase Type 1) highlights its …

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Functional neurological disorders
Memory processing by hippocampal adult-born neurons

by myneuronews May 9, 2025

by myneuronews May 9, 2025

Memory Functions of Adult-Born Neurons Recent research has shed light on the remarkable role of …

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Functional neurological disorders
Hypoxic preconditioning modulates BDNF signaling to alleviate depression-like behaviors in mice and its whole transcriptome sequencing analysis

by myneuronews May 2, 2025

by myneuronews May 2, 2025

Mechanisms of Hypoxic Preconditioning Hypoxic preconditioning (HP) is an intriguing physiological process whereby exposure to …

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Functional neurological disorders
Silencer variants are key drivers of gene upregulation in Alzheimer’s disease

by myneuronews April 29, 2025

by myneuronews April 29, 2025

Silencer Variants and Gene Regulation Recent advancements in genetic research have shed light on the …

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Functional neurological disorders
Milestone Review: Unlocking the Proteomics of Glycine Receptor Complexes

by myneuronews April 26, 2025

by myneuronews April 26, 2025

Proteomic Analysis of Glycine Receptors The detailed examination of glycine receptors (GlyRs) through proteomic analysis …

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Functional neurological disorders
Gut Neuropeptide Involvement in Parkinson’s Disease

by myneuronews April 25, 2025

by myneuronews April 25, 2025

Gut Neuropeptides and Their Role in Neurodegeneration Gut neuropeptides are crucial biochemical messengers that play …

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Functional neurological disorders
Understanding the Pathophysiology of Functional Movement Disorder (FMD)

by Ioannis Mavroudis October 26, 2024

by Ioannis Mavroudis October 26, 2024

Introduction Functional Movement Disorder (FMD) is a neurological condition where patients experience abnormal movements, such …

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Functional neurological disorders
Misdiagnosis in Functional Neurological Disorders (FND)

by Ioannis Mavroudis May 15, 2024

by Ioannis Mavroudis May 15, 2024

Functional Neurological Disorders (FND) present with symptoms that lack clear organic causes and mimic other …

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Guillain-Barré Syndrome Induced by Mycoplasma Pneumoniae: A Non-classical Presentation
Study Overview This study investigates a unique case of Guillain-Barré Syndrome (GBS) that arose following…
The Role of Metabolic Testing in the Diagnostic Evaluation of Adult NORSE: A Retrospective, Single-Centre Study
Study Overview The study under discussion investigates the significance of metabolic testing in diagnosing non-acute…
Alcohol Intake and Cardiovascular Outcomes in Patients With Atrial Fibrillation: RE-LY AF Registry Analysis
Study Overview The analysis derived from the RE-LY AF registry explores the implications of alcohol…
Long-term outcomes in leucine-rich glioma inactivated-1 autoimmune encephalitis and associated biomarkers of inflammation and neuronal and glial injury
Long-term outcomes Long-term outcomes in patients with leucine-rich glioma inactivated-1 (LGI1) autoimmune encephalitis are a…
Understanding personal preferences to promote exercise adherence in Parkinson’s disease
Understanding Preferences for Exercise Exploring individuals’ exercise preferences is essential in tailoring interventions that resonate…

Time-limited association between plasma transfusion and mortality in pediatric traumatic brain injury
CONCLUSION: This study reports a significant association between early plasma administration and a lower risk of 4-hour mortality among children with severe TBI that does not persist at or beyond 24 hours. While these data suggest that plasma resuscitation may extend the window for lifesaving intervention, additional prospective data are needed.
Cellular mechanisms of traumatic brain injury
Mild traumatic brain injury (mTBI) is an acute injury with immediate and medium-term symptom presentation. However, our mechanistic understanding of mTBI and how mechanical loading of soft cellular tissues leads to injury is limited. The aim of this review is to introduce this interdisciplinary field to non-experts and provide an overview of our current understanding […]
Comparing the sensitivity and specificity of novel motor assessments for traumatic brain injury
CONCLUSION: MMC-mediated tests are sensitive and specific (compared to traditional clinical tests) and have potential to fill a gap in clinical care of TBI.
Chronic Traumatic Encephalopathy Neuropathologic Change Is Not Associated With Suicide in Former Athletes
There are important knowledge gaps and misunderstandings relating to chronic traumatic encephalopathy (CTE). A systematic review and meta-analysis, published in April of 2025, was designed to examine the prevalence, risk factors, and potential outcomes of CTE neuropathologic change (CTE-NC) in former athletes and concluded that suicide was a potential outcome of CTE-NC (Qi et al., […]
Regional and Global Changes in Brain Structure 1-Year Post Pediatric "Mild" Traumatic Brain Injury
OBJECTIVE: Despite the high prevalence of pediatric "mild" traumatic brain injury (pmTBI), very little is known about the long-term effects of injury on brain structure and how injuries manifest in the context of dynamic and regionally specific neurodevelopmental changes.