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pathophysiology of FND

Functional neurological disorders
Microglia-drive IRF8 upregulates complement pathway in Parkinson’s disease

by myneuronews June 2, 2025

by myneuronews June 2, 2025

Microglia and Parkinson’s Disease Pathophysiology Microglia, the resident immune cells of the central nervous system, …

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Functional neurological disorders
Presymptomatic Biological, Structural, and Functional Diagnostic Biomarkers of Autism Spectrum Disorder

by myneuronews May 20, 2025

by myneuronews May 20, 2025

Biological Markers of Autism Spectrum Disorder Biological markers for Autism Spectrum Disorder (ASD) represent a …

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Functional neurological disorders
HSD17B1-mediated trophoblast differentiation lowers estrogen levels in early-onset preeclampsia

by myneuronews May 20, 2025

by myneuronews May 20, 2025

HSD17B1 Role in Trophoblast Differentiation The study of HSD17B1 (Hydroxysteroid Dehydrogenase Type 1) highlights its …

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Functional neurological disorders
Memory processing by hippocampal adult-born neurons

by myneuronews May 9, 2025

by myneuronews May 9, 2025

Memory Functions of Adult-Born Neurons Recent research has shed light on the remarkable role of …

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Functional neurological disorders
Hypoxic preconditioning modulates BDNF signaling to alleviate depression-like behaviors in mice and its whole transcriptome sequencing analysis

by myneuronews May 2, 2025

by myneuronews May 2, 2025

Mechanisms of Hypoxic Preconditioning Hypoxic preconditioning (HP) is an intriguing physiological process whereby exposure to …

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Functional neurological disorders
Silencer variants are key drivers of gene upregulation in Alzheimer’s disease

by myneuronews April 29, 2025

by myneuronews April 29, 2025

Silencer Variants and Gene Regulation Recent advancements in genetic research have shed light on the …

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Functional neurological disorders
Milestone Review: Unlocking the Proteomics of Glycine Receptor Complexes

by myneuronews April 26, 2025

by myneuronews April 26, 2025

Proteomic Analysis of Glycine Receptors The detailed examination of glycine receptors (GlyRs) through proteomic analysis …

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Functional neurological disorders
Gut Neuropeptide Involvement in Parkinson’s Disease

by myneuronews April 25, 2025

by myneuronews April 25, 2025

Gut Neuropeptides and Their Role in Neurodegeneration Gut neuropeptides are crucial biochemical messengers that play …

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Functional neurological disorders
Understanding the Pathophysiology of Functional Movement Disorder (FMD)

by Ioannis Mavroudis October 26, 2024

by Ioannis Mavroudis October 26, 2024

Introduction Functional Movement Disorder (FMD) is a neurological condition where patients experience abnormal movements, such …

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Functional neurological disorders
Misdiagnosis in Functional Neurological Disorders (FND)

by Ioannis Mavroudis May 15, 2024

by Ioannis Mavroudis May 15, 2024

Functional Neurological Disorders (FND) present with symptoms that lack clear organic causes and mimic other …

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IGF-1 as a biomarker for symptom severity in adolescents with traumatic brain injury
CONCLUSIONS: Adolescents with msTBI experienced greater post-injury symptom severity and anxiety than those with mTBI. Low IGF-1 levels correlated with greater post-injury symptom severity, anxiety, and depression (msTBI only), supporting IGF-1 as a potential biomarker in adolescent TBI.
Video analysis of head impacts in top-level female football players: a cohort study
This study aimed at exploring the exposure of head impacts, i.e. headers and non-headers, in top-level female football players. The study included all teams (n = 10) and players (n = 238) in the Norwegian Women's Premier League during the 2023 season. Video analysis was used to register headers and non-headers in the 135 matches […]
A Comparative Study on the Trends of Blood Glucose, Serum Triglycerides, and CRP-Based Levels in Correlation with GCS among Patients with Traumatic Head Injury
CONCLUSION: The decreasing trend in glucose levels in group 2 and increasing trend in CRP levels in group 1 are due to the same pathogenesis, which is associated with the severity of head injury. Increased trends in triglyceride levels were seen in both the groups. Since the association of levels of these parameters and their […]
Longitudinal assessment of brain injury biomarker neurofilament light in female football players during a competitive season of football heading
This prospective cohort study aimed to longitudinally assess the brain injury biomarker plasma neurofilament light (NfL) and its relationship with football heading exposure in female football players during a competitive season. Forty-nine collegiate female football players were recruited to participate in the study, 29 voluntarily consented and enrolled. Blood samples were collected every 3-4 weeks […]
Exploring the effects of a multicomponent phytoceutical health product in a Drosophila melanogaster ageing and repetitive concussion model
CONCLUSIONS: The findings validate that D. melanogaster is a suitable system to mimic the effects of repetitive concussions and evaluate the effects of novel health products.