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pathophysiology of FND

Functional neurological disorders
Microglia-drive IRF8 upregulates complement pathway in Parkinson’s disease

by myneuronews June 2, 2025

by myneuronews June 2, 2025

Microglia and Parkinson’s Disease Pathophysiology Microglia, the resident immune cells of the central nervous system, …

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Functional neurological disorders
Presymptomatic Biological, Structural, and Functional Diagnostic Biomarkers of Autism Spectrum Disorder

by myneuronews May 20, 2025

by myneuronews May 20, 2025

Biological Markers of Autism Spectrum Disorder Biological markers for Autism Spectrum Disorder (ASD) represent a …

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Functional neurological disorders
HSD17B1-mediated trophoblast differentiation lowers estrogen levels in early-onset preeclampsia

by myneuronews May 20, 2025

by myneuronews May 20, 2025

HSD17B1 Role in Trophoblast Differentiation The study of HSD17B1 (Hydroxysteroid Dehydrogenase Type 1) highlights its …

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Functional neurological disorders
Memory processing by hippocampal adult-born neurons

by myneuronews May 9, 2025

by myneuronews May 9, 2025

Memory Functions of Adult-Born Neurons Recent research has shed light on the remarkable role of …

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Functional neurological disorders
Hypoxic preconditioning modulates BDNF signaling to alleviate depression-like behaviors in mice and its whole transcriptome sequencing analysis

by myneuronews May 2, 2025

by myneuronews May 2, 2025

Mechanisms of Hypoxic Preconditioning Hypoxic preconditioning (HP) is an intriguing physiological process whereby exposure to …

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Functional neurological disorders
Silencer variants are key drivers of gene upregulation in Alzheimer’s disease

by myneuronews April 29, 2025

by myneuronews April 29, 2025

Silencer Variants and Gene Regulation Recent advancements in genetic research have shed light on the …

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Functional neurological disorders
Milestone Review: Unlocking the Proteomics of Glycine Receptor Complexes

by myneuronews April 26, 2025

by myneuronews April 26, 2025

Proteomic Analysis of Glycine Receptors The detailed examination of glycine receptors (GlyRs) through proteomic analysis …

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Functional neurological disorders
Gut Neuropeptide Involvement in Parkinson’s Disease

by myneuronews April 25, 2025

by myneuronews April 25, 2025

Gut Neuropeptides and Their Role in Neurodegeneration Gut neuropeptides are crucial biochemical messengers that play …

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Functional neurological disorders
Understanding the Pathophysiology of Functional Movement Disorder (FMD)

by Ioannis Mavroudis October 26, 2024

by Ioannis Mavroudis October 26, 2024

Introduction Functional Movement Disorder (FMD) is a neurological condition where patients experience abnormal movements, such …

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Functional neurological disorders
Misdiagnosis in Functional Neurological Disorders (FND)

by Ioannis Mavroudis May 15, 2024

by Ioannis Mavroudis May 15, 2024

Functional Neurological Disorders (FND) present with symptoms that lack clear organic causes and mimic other …

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<em>Taking Control of Your Functional Cognitive Symptoms: Workbook</em>-A Novel Intervention
CONCLUSIONS: This promising new multimodality behavioral health intervention can be considered to be in stage 1 (i.e., intervention generation, refinement, modification, adaptation, and pilot testing). Further pilot testing is being conducted and will need to be followed by traditional efficacy testing (in stage 2).
Hemodynamic Oscillations in Mild TBI During Postural Change: An fNIRS Pilot Study
We demonstrate that low-frequency oscillations (LFOs) in cerebral hemodynamics, measured by frequency-domain functional near-infrared spectroscopy (FD-fNIRS), reflect altered cerebral hemodynamic oscillations in mild traumatic brain injury (mTBI). In a pilot study of two mTBI and 13 healthy subjects undergoing head-of-bed positional changes, we analyzed total hemoglobin concentration (THC), oxyhemoglobin (HbO), and deoxyhemoglobin (Hb) dynamics using […]
Normative Data for Single- and Dual-Task Tandem Gait Performance in Collegiate Athletes
CONCLUSION: Our results provide robust normative data for single- and dual-task tandem gait stratified by relevant patient factors that can be immediately used by clinicians and future researchers. Future research should compare the use of individual baseline versus normative data for acute concussion tracking.
Examination of Resource Utilization and Adverse Outcomes Among Isolated Traumatic Brain Injury Patients Using Modified Brain Injury Guidelines
BackgroundMild traumatic brain injuries (TBI) are often overmanaged, resulting in an inefficient use of time and resources. The Brain Injury Guidelines was developed and subsequently improved as the modified Brain Injury Guidelines (mBIG) to help standardize TBI management. This study evaluates how adopting the mBIG criteria could improve TBI management at our institution.Materials and MethodsThis […]
Accented Speech Perception in Noise After Mild Traumatic Brain Injury
CONCLUSIONS: Individuals who have had a concussion in the past may experience mild impairments in perception of nonnative-accented speech in noise. Additionally, challenging listening conditions may exacerbate existing symptoms associated with mTBI.