Tag:

pathophysiology

Traumatic brain injury
Sensory driven neurophysiological mechanisms of concussion: a parsimonious and falsifiable theory

by myneuronews May 15, 2025

by myneuronews May 15, 2025

Overview of Neurophysiological Mechanisms Understanding the neurophysiological mechanisms underlying concussion involves delving into the complex …

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Functional neurological disorders
DG9 boosts PMO nuclear uptake and exon skipping to restore dystrophic muscle and cardiac function

by myneuronews May 14, 2025

by myneuronews May 14, 2025

Mechanisms of DG9 Action DG9 has emerged as a pivotal compound in the realm of …

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Functional neurological disorders
Association of APOC1 with cortical atrophy during conversion to Alzheimer’s disease

by myneuronews May 14, 2025

by myneuronews May 14, 2025

Association of Apoc1 with Alzheimer’s Disease Recent research has underscored the significance of the apolipoprotein …

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Movement Disorders
Safety and tolerability of intravenous liposomal GM1 in patients with Parkinson disease: A single-center open-label clinical phase I trial (NEON trial)

by myneuronews May 13, 2025

by myneuronews May 13, 2025

Study Overview The study aimed to investigate the safety and tolerability of intravenous liposomal GM1 …

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Functional neurological disorders
Research Progress on BDNF and Depression

by myneuronews May 13, 2025

by myneuronews May 13, 2025

Understanding BDNF in Depression Brain-Derived Neurotrophic Factor (BDNF) is a crucial protein that supports the …

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Dementia
Validating the Amyloid Cascade Through the Revised Criteria of Alzheimer’s Association Workgroup 2024 for Alzheimer Disease

by myneuronews May 13, 2025

by myneuronews May 13, 2025

Amyloid Cascade Hypothesis and Alzheimer Disease The Amyloid Cascade Hypothesis is a prominent concept in …

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Movement Disorders
A Rare Case of Bilateral Xanthomatosis of Tendon of Achilles: A Case Report

by myneuronews May 12, 2025

by myneuronews May 12, 2025

Background of Bilateral Xanthomatosis Bilateral xanthomatosis is a rare condition characterized by the accumulation of …

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Functional neurological disorders
Association of type 1 stiff-person syndrome and insulinoma: a case report and narrative review

by myneuronews May 12, 2025

by myneuronews May 12, 2025

Clinical Presentation and Diagnosis The clinical presentation of type 1 stiff-person syndrome (SPS) and its …

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Functional neurological disorders
Apolipoprotein E (APOE) and Alzheimer’s disease risk in a Ugandan population: A pilot case-control study

by myneuronews May 12, 2025

by myneuronews May 12, 2025

Apolipoprotein E Genotypes and Alzheimer’s Disease The study investigated the relationship between different genotypes of …

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Functional neurological disorders
Electrophysiological characterisation of intranigral-grafted hiPSC-derived dopaminergic neurons in a mouse model of Parkinson’s disease

by myneuronews May 9, 2025

by myneuronews May 9, 2025

Electrophysiological Properties of hiPSC-Derived Neurons The study begins by examining the electrophysiological properties of human-induced …

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Excessive emotional reactivity in a case of behavioral variant frontotemporal dementia with amyotrophic lateral sclerosis
Case Presentation The patient, a 60-year-old male, presented with a progressive decline in social functioning…
The effects of radiation therapy on the brain: implications for management
Effects of Radiation Therapy on Brain Function Radiation therapy, a common treatment modality for various…
A rare neurological odyssey: Gastric adenocarcinoma and leptomeningeal carcinomatosis – A Peruvian case study
Case Presentation A 56-year-old male presented to the hospital with a complex clinical history, including…
Aging With Strength: Functional Training to Support Independence and Quality of Life
Importance of Functional Training Functional training is a crucial aspect of exercise regimens, especially for…
Uncovering Putative Causal Non-Coding RNAs in Acute and Chronic Myeloid Leukemia: A Genome-Wide Mendelian Randomization Study
Study Overview The investigation aimed to explore the role of non-coding RNAs in the development…

Quantification of the cerebral pressure-flow relationship directional sensitivity: Reliability of shorter repeated squat-stand durations
The magnitude of changes in middle cerebral artery mean blood velocity (MCAv) is attenuated when mean arterial pressure (MAP) increases compared with when MAP decreases. This directional sensitivity has been characterized using a time-corrected ratio calculated on MCAv and MAP changes induced by repeated squat-stands (RSS) at 0.05 and 0.10 Hz for 300 s (∆MCAv(T)/∆MAP(T)). […]
Distinct clinical phenotypes and their neuroanatomic correlates in chronic traumatic brain injury
Accumulating evidence of heterogeneous long-term outcomes after traumatic brain injury (TBI) has challenged longstanding approaches to TBI outcome classification that are largely based on global functioning. A lack of studies with clinical and biomarker data from individuals living with chronic (>1 year post-injury) TBI has precluded refinement of long-term outcome classification ontology. Multimodal data in […]
A Comparison of Quantitative Pupillometry and VOMS in Division 1 Female Soccer Players
Background and Objectives: Vision uses about half of the pathways within the brain, and these anatomical structures are susceptible to injury in concussion. Authors have suggested that subconcussive head impacts, common in soccer, may disrupt visual function. The following study aimed to explore and compare quantitative pupillometry and Vestibular Ocular Motor Screening (VOMS) in female […]
Acceptability of a Brain-Injury-Tailored Yoga and Meditation Program Among Female Patients with Concussion
Background: Although concussion symptoms often resolve within 4-6 weeks, for a minority of patients, persistent postconcussion symptoms (PPCS), such as headaches, fatigue, and mood disturbances, may continue for months or years following a head injury. Rehabilitation of this group-often female-is crucial for reducing health and gender disparities in concussion recovery. A recent report by the […]
The national football league concussion settlement race-norming incident in context
CONCLUSION: Replacing race-norms involves using performance-based estimates of preexisting skill level that are individualized and not subject to racial profiling. In research, racial/ethnic group comparisons give way to the study of measurable sociocultural dimensions on which these groupings differ that potentially impact neuropsychological test scores. To date, few such dimensions have demonstrated incremental contributions beyond […]