Tag:

pathophysiology

Dementia
Cortical inhibitory and facilitatory alterations in the continuum of alpha-synucleinopathies

by myneuronews July 25, 2025

by myneuronews July 25, 2025

Cortical Inhibition in Alpha-Synucleinopathies Alterations in cortical inhibition have been observed in alpha-synucleinopathies, which include …

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Functional neurological disorders
Neuroimaging correlates of genetics in patients with Wilson’s disease

by myneuronews July 24, 2025

by myneuronews July 24, 2025

Neuroimaging Findings in Wilson’s Disease Neuroimaging plays a crucial role in understanding Wilson’s disease, a …

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Functional neurological disorders
Neuroimaging correlates of genetics in patients with Wilson’s disease

by myneuronews July 24, 2025

by myneuronews July 24, 2025

Neuroimaging Findings in Wilson’s Disease Neuroimaging findings in Wilson’s disease reveal significant alterations in brain …

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Functional neurological disorders
The Frmpd3 Protein Regulates Susceptibility to Epilepsy by Combining with GRIP and GluA2

by myneuronews July 23, 2025

by myneuronews July 23, 2025

Role of Frmpd3 in Epilepsy The study presents compelling evidence that Frmpd3 plays a significant …

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Functional neurological disorders
Integrated Transcriptomic Analysis Provided Diagnostic and Pathophysiological Insights for Epilepsy

by myneuronews July 23, 2025

by myneuronews July 23, 2025

Integrated Transcriptomic Insights Recent advancements in transcriptomic analysis have opened new avenues for understanding the …

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Functional neurological disorders
The Frmpd3 Protein Regulates Susceptibility to Epilepsy by Combining with GRIP and GluA2

by myneuronews July 23, 2025

by myneuronews July 23, 2025

Frmpd3 Function in Epilepsy The study of the Frmpd3 protein reveals its significant role in …

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Functional neurological disorders
Integrated Transcriptomic Analysis Provided Diagnostic and Pathophysiological Insights for Epilepsy

by myneuronews July 23, 2025

by myneuronews July 23, 2025

Integrated Transcriptomic Findings The study employs an integrated transcriptomic approach, utilizing high-throughput RNA sequencing to …

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Functional neurological disorders
Integrated Single-Cell and Spatial Transcriptomic Analysis Identifies ISR-Related Genes Driving Immune Regulation in Parkinson’s Disease

by myneuronews July 21, 2025

by myneuronews July 21, 2025

Integrated Transcriptomic Approaches The integration of transcriptomic approaches offers a powerful way to glean insights …

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Functional neurological disorders
Rhynchophylline Reverses Obesity in High-Fat Diet-Induced Obese Rats by Regulating the Inflammatory Cascade and Blocking 3‑hydroxy-3-methylglutaryl Coenzyme A Reductase

by myneuronews July 21, 2025

by myneuronews July 21, 2025

Effects of Rhynchophylline on Obesity In recent studies examining the effects of rhynchophylline on obesity, …

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Traumatic brain injury
Language impairment is associated with faster progression in progressive supranuclear palsy-Richardson syndrome

by myneuronews July 19, 2025

by myneuronews July 19, 2025

Study overview The research focused on the connection between language impairments and the rate of …

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First detection of echovirus 18 associated with aseptic meningitis in a child in Niger Republic, 2024: a case report
Background of Echovirus 18 Echovirus 18, part of the Enterovirus genus within the Picornaviridae family,…
Mitochondrial dysfunction, a new marker warning of neuropsychiatric disorder risk: evidence from genetics and epidemiology
Mitochondrial Dysfunction and Neuropsychiatric Disorders Mitochondria, often referred to as the powerhouses of the cell,…
Assessing knowledge and attitudes towards sports-related concussion among university students in Saudi Arabia: a cross-sectional study
Study Overview This research examines the understanding and perceptions surrounding sports-related concussions among university students…
Stabilizing microtubules increases acute cellular injury at high strain rates
Study Overview This study investigates the relationship between the stabilization of microtubules and the susceptibility…
Pre-injury sleep disturbance as a moderator of cognitive functioning in children and adolescents with mild traumatic brain injury
Study Overview The research investigates the complex interplay between pre-injury sleep disturbances and cognitive outcomes…

Evaluating cognitive performance using cognitive performance using the National Institutes of Health Toolbox Cognitive Battery in children with traumatic brain injury
CONCLUSIONS: The NIH TB-CB detects worse cognitive functioning in children with severe TBI six-twelve months post-injury, largely driven by differences in Fluid Cognition. Our findings suggest the NIH TB-CB may be suitable for monitoring cognition in children with TBI.
Impact of Mild Traumatic Brain Injury on Sleep Patterns in Younger Individuals: A Systematic Review
Concussions or mild traumatic brain injuries (mTBI) are a frequent outcome of contact sports, and adolescents and young adults face a disproportionately higher risk of repeated injury. Prominent sequelae of mTBI observed in younger populations include anxiety, decreased sleep quality, insomnia, and impaired cognitive performance, all of which can extend beyond the acute phase of […]
Clinical utility of diffusion tensor imaging in sport-related concussion: a systematic review
CONCLUSIONS: Future research efforts should implement standardized methods capable of accounting for inter-individual differences to further validate DTI's role as an objective biomarker of SRC.
Olfactory dysfunction with traumatic brain injury and posttraumatic-stress symptoms in post-deployed military personnel
INTRODUCTION: Prior research suggests that olfactory dysfunction may occur following a traumatic brain injury (TBI) due to structural injury to the olfactory peripheral or central networks. Olfaction may also be affected in posttraumatic stress disorder (PTSD) due to traumatic re-experiencing. Given the relevance of both TBI and PTSD to the military and veteran populations, the […]
Evaluation of betaxolol in improving the glasgow outcome scale extended (GOSE) of the acute phase of patients with mild to moderate Traumatic Brain Injury: a double blinded randomized clinical trial
BACKGROUND: Traumatic brain injury (TBI) is one of the most important causes of morbidity and mortality. It is important to have an effective treatment that can improve the quality of life and cognitive functions of these patients. Betaxolol, a selective beta-1 beta-blocker, may be effective in improving the symptoms of mild to moderate TBI.