Tag:

pathophysiology

Functional neurological disorders
Human PrP E219K: a new and promising substrate for robust RT-QuIC amplification of human prions with potential for strain discrimination

by myneuronews July 10, 2025

by myneuronews July 10, 2025

Overview of Prion Amplification Techniques Prion diseases are a group of progressive neurodegenerative disorders characterized …

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Functional neurological disorders
Current Clinical Applications of Structural MRI in Neurological Disorders

by myneuronews July 10, 2025

by myneuronews July 10, 2025

Current Applications in Neurology Structural MRI has emerged as a crucial tool in the diagnosis …

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Functional neurological disorders
Insights into the Diagnosis, Treatment, and Management of Prion Diseases

by myneuronews July 10, 2025

by myneuronews July 10, 2025

Understanding Prion Diseases Prion diseases, a unique category of neurodegenerative disorders, are caused by misfolded …

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Dementia
Discrepancies between CSF biomarker and PET determinations of elevated brain amyloid and their prognostic significance

by myneuronews July 9, 2025

by myneuronews July 9, 2025

Study Overview The ongoing challenge of accurately diagnosing Alzheimer’s disease and other neurodegenerative conditions has …

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Headaches
Idiopathic hypertrophic pachymeningitis (IHP) causing headache in a young female

by myneuronews July 7, 2025

by myneuronews July 7, 2025

Study Overview This study investigates idiopathic hypertrophic pachymeningitis (IHP), a rare neurological condition characterized by …

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Functional neurological disorders
Retrospective Analysis of Factors Associated with a Prolonged Nucleic Acid Conversion Time in Patients with COVID-19 at Fangcang Shelter Hospital

by myneuronews July 7, 2025

by myneuronews July 7, 2025

Background of Nucleic Acid Conversion in COVID-19 The process of nucleic acid conversion in COVID-19 …

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Dementia
Machine-learning based strategy identifies a robust protein biomarker panel for Alzheimer’s disease in cerebrospinal fluid

by myneuronews July 4, 2025

by myneuronews July 4, 2025

Study Overview The study examines the potential for machine-learning techniques to identify a reliable protein …

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Traumatic brain injury
White matter tract differences in persistent post-traumatic headache, migraine, and healthy controls: a diffusion tensor imaging study

by myneuronews July 4, 2025

by myneuronews July 4, 2025

Study Overview This study investigates the differences in white matter tracts among individuals experiencing persistent …

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Traumatic brain injury
Comparative analysis of plasma and salivary S100B as predictors of traumatic brain injury severity according to GCS and MAIS/head

by myneuronews July 4, 2025

by myneuronews July 4, 2025

Study Overview The research investigates the efficacy of two biological markers, S100B protein levels in …

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Functional neurological disorders
Unveiling cortical criticality changes along the prodromal to the overt continuum of alpha-synucleinopathy

by myneuronews July 3, 2025

by myneuronews July 3, 2025

Cortical Criticality in Alpha-Synucleinopathy The concept of cortical criticality refers to the brain’s ability to …

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Herpes simplex virus associated rhomboencephalitis mimicking demyelination: a case report
Study Overview This case report focuses on a unique instance of rhomboencephalitis, an inflammation of…
Assessing the health-related quality of life in informal caregivers of Alzheimer’s Disease: evidence from Malaysia
Health-Related Quality of Life in Caregivers The health-related quality of life (HRQoL) among informal caregivers…
Using Genetics to Shed Light on the Scientific Gray Zone of Functional Seizures
Genetic Factors in Functional Seizures Recent studies have begun to uncover the genetic underpinnings that…
2025 guideline update to acute treatment of migraine for adults in the emergency department: The American Headache Society evidence assessment of parenteral pharmacotherapies
Study Overview This comprehensive review focuses on the advances in the management of acute migraine…
Knee Biomechanics in Individuals With a Recent Concussion During Jump-Landing Tasks
Background and Rationale The relationship between concussions and subsequent physical performance, particularly in biomechanical tasks,…

MRI investigation of orientation-dependent changes in microstructure and function in a mouse model of mild traumatic brain injury
While neuroimaging studies have revealed notable white matter damage following mild traumatic brain injury (mTBI), the specific tracts and brain regions affected vary widely across studies. Here, we explored whether the spatial orientation of white matter tracts influences susceptibility to repeated mTBI, predicting that tracts oriented orthogonal to the axis of rotation of the head […]
Impulse Dyscontrol Symptoms Are Related to Amyloid Beta in Patients With Subjective Cognitive Decline and Mild Cognitive Impairment
CONCLUSION: The study identified a significant correlation between domain C of the MBI-C and CSF beta-amyloid peptide analysing Brazilian patients with SCD and MCI. The results reinforce the hypothesis of the relationship between impulsivity symptoms and amyloid pathology. Further studies involving the correlations between MBI and neuropsychiatric symptoms with AD CSF biomarkers are necessary.
Female, woman and/or girl Athlete Injury pRevention (FAIR) practical recommendations: International Olympic Committee (IOC) consensus meeting held in Lausanne, Switzerland, 2025
Female, woman and/or girl athletes' sport participation rates are rising and associated with high injury rates and burden. Using best-practice consensus methodology, we developed recommendations to guide injury prevention for female/woman/girl athletes. The Female/woman/girl Athlete Injury pRevention (FAIR) International Olympic Committee Consensus meeting was held from 31 March to 2 April 2025 (Lausanne, Switzerland).The FAIR […]
The road to consensus: lessons learned from FAIR and recommendations for future consensus activities
No abstract
Video analysis of potential head injury situations in FIFA Beach Soccer World Cups
CONCLUSIONS: The findings demonstrated that the incidence of potential head injuries in beach soccer is 3.2 per-match, which is 7.6× higher than the data previously reported in men's association football. Player-to-player impact, unintentional ball impacts and overhead kicks contributed significantly to this elevated incidence. The observation that 17.9 % of potential head injuries exhibited visible […]