Tag:

pathophysiology

Traumatic brain injury
Sensory driven neurophysiological mechanisms of concussion: a parsimonious and falsifiable theory

by myneuronews May 15, 2025

by myneuronews May 15, 2025

Overview of Neurophysiological Mechanisms Understanding the neurophysiological mechanisms underlying concussion involves delving into the complex …

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Functional neurological disorders
Association of APOC1 with cortical atrophy during conversion to Alzheimer’s disease

by myneuronews May 14, 2025

by myneuronews May 14, 2025

Association of Apoc1 with Alzheimer’s Disease Recent research has underscored the significance of the apolipoprotein …

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Functional neurological disorders
DG9 boosts PMO nuclear uptake and exon skipping to restore dystrophic muscle and cardiac function

by myneuronews May 14, 2025

by myneuronews May 14, 2025

Mechanisms of DG9 Action DG9 has emerged as a pivotal compound in the realm of …

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Dementia
Validating the Amyloid Cascade Through the Revised Criteria of Alzheimer’s Association Workgroup 2024 for Alzheimer Disease

by myneuronews May 13, 2025

by myneuronews May 13, 2025

Amyloid Cascade Hypothesis and Alzheimer Disease The Amyloid Cascade Hypothesis is a prominent concept in …

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Functional neurological disorders
Research Progress on BDNF and Depression

by myneuronews May 13, 2025

by myneuronews May 13, 2025

Understanding BDNF in Depression Brain-Derived Neurotrophic Factor (BDNF) is a crucial protein that supports the …

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Functional neurological disorders
Apolipoprotein E (APOE) and Alzheimer’s disease risk in a Ugandan population: A pilot case-control study

by myneuronews May 12, 2025

by myneuronews May 12, 2025

Apolipoprotein E Genotypes and Alzheimer’s Disease The study investigated the relationship between different genotypes of …

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Functional neurological disorders
Association of type 1 stiff-person syndrome and insulinoma: a case report and narrative review

by myneuronews May 12, 2025

by myneuronews May 12, 2025

Clinical Presentation and Diagnosis The clinical presentation of type 1 stiff-person syndrome (SPS) and its …

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Functional neurological disorders
Electrophysiological characterisation of intranigral-grafted hiPSC-derived dopaminergic neurons in a mouse model of Parkinson’s disease

by myneuronews May 9, 2025

by myneuronews May 9, 2025

Electrophysiological Properties of hiPSC-Derived Neurons The study begins by examining the electrophysiological properties of human-induced …

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Functional neurological disorders
Memory processing by hippocampal adult-born neurons

by myneuronews May 9, 2025

by myneuronews May 9, 2025

Memory Functions of Adult-Born Neurons Recent research has shed light on the remarkable role of …

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Functional neurological disorders
GWAS by Subtraction to Disentangle RBD Genetic Background from α-Synucleinopathies

by myneuronews May 7, 2025

by myneuronews May 7, 2025

Background and Rationale The study of genetic factors influencing neurological conditions has gained momentum in …

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Discipline-specific responses to a complex migraine case: a vignette-based survey among neurologists, psychiatrists, and family physicians
Study Overview The investigation aimed to explore the variations in clinical responses to a complex…
Differences in inflammatory markers, mitochondrial function, and synaptic proteins in male and female Alzheimer’s disease post mortem brains
Inflammatory Markers Comparison Research into Alzheimer’s disease has increasingly highlighted the significance of inflammation in…
Propofol Exposure Precipitating a Functional Movement Disorder: A Case Report
Propofol’s Role in Functional Movement Disorders Propofol, a widely used intravenous anesthetic, is renowned for…
Functional left hemiparesis
Overview of Functional Left Hemiparesis Functional left hemiparesis is a type of movement disorder characterized…
Blocking axon-glial mechanotransduction to prevent concussive brain injury
Study Overview The research focuses on preventing concussive brain injuries through the inhibition of mechanotransduction…

Psychometrics of a fear-avoidance measure adapted for youth with persistent postconcussive symptoms: Fear of Concussive Symptoms Questionnaire (FOCSQ) child and parent-proxy versions
CONCLUSIONS: The FOCSQ is a reliable and valid measure of fear-avoidance in youth with concussion, and future research might explore whether this measure could be used to identify youth at risk for prolonged recovery. (PsycInfo Database Record (c) 2025 APA, all rights reserved).
Differences in narrative discourse ability in traumatic brain injury and a neurotypical comparison group: Influence of age, education, and sex
CONCLUSIONS: TBI disrupts both narrative discourse comprehension and production ability. Findings underscore the need to evaluate both narrative comprehension and production performance following TBI. Age, education, and sex did not influence discourse outcomes.
Influence of traumatic brain injury on serum levels of pituitary, thyroid, adrenal and gonadal hormones
This study explores the clinical significance of dynamic changes in pituitary, thyroid, adrenal and gonadal hormones following traumatic brain injury (TBI). The study cohort included 90 patients with mild, moderate, or severe TBI and 30 healthy volunteers as the control group. Serum levels of total triiodothyronine (TT3), thyroxine (TT4), free triiodothyronine (FT3), free thyroxine (FT4), […]
Neural oscillation mechanisms of repetitive subconcussive impacts: a network study of microstate-specific cross-frequency coupling
CONCLUSIONS: SC exposure induces MCFCNs abnormalities resembling central pain syndromes, even in the absence of overt symptoms. These findings suggest that interactions within MCFCNs may serve as potential early biomarkers for headache vulnerability and chronicity, warranting further exploration in longitudinal studies and targeted neurointerventions.
Impact of > 24 h sustained wakefulness and subsequent recovery sleep on time-dependent changes in microRNA factors of individuals with post-acute phase mild traumatic brain injury
INTRODUCTION: The purpose of the present study was to determine whether mild traumatic brain injury (mTBI+) results in latent changes in microRNA expression profiles across an episode of total sleep deprivation (TSD).