Tag:

pathophysiology

Traumatic brain injury
Multi-ancestry genome-wide meta-analysis of 56,241 individuals identifies known and novel cross-population and ancestry-specific associations as novel risk loci for Alzheimer’s disease

by myneuronews July 17, 2025

by myneuronews July 17, 2025

Study Overview The study aimed to explore the genetic underpinnings of Alzheimer’s disease (AD) through …

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Functional neurological disorders
A novel cause of type 1 von Willebrand disease: impaired exocytosis of Weibel-Palade bodies due to biallelic MADD variants

by myneuronews July 16, 2025

by myneuronews July 16, 2025

Novel Mechanism of Type 1 Von Willebrand Disease Recent research has uncovered a previously unrecognized …

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Functional neurological disorders
Transcranial magnetic stimulation as a primer for rapid improvement in functional neurological disorder: a case series

by myneuronews July 15, 2025

by myneuronews July 15, 2025

Background on Functional Neurological Disorder Functional Neurological Disorder (FND) is a condition characterized by neurological …

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Functional neurological disorders
Identifying pyroptosis- and inflammation-related genes in spinal cord injury based on bioinformatics analysis

by myneuronews July 14, 2025

by myneuronews July 14, 2025

Gene Identification Methods To identify genes that play a role in pyroptosis and inflammation following …

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Functional neurological disorders
Immunological Correlation in Different Cutaneous Clinical Types of Lupus Erythematosus in the Bulgarian Population

by myneuronews July 14, 2025

by myneuronews July 14, 2025

Immunological Profile of Lupus Erythematosus The immunological profile of Lupus Erythematosus (LE) reveals a complex …

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Functional neurological disorders
Role of ALOX5AP in the pathogenesis of cerebral small vessel disease: impact of inflammation and lipid metabolism dysregulation

by myneuronews July 12, 2025

by myneuronews July 12, 2025

Pathophysiological Mechanisms of ALOX5AP The role of ALOX5AP (Arachidonate 5-Lipoxygenase Activating Protein) in the pathogenesis …

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Functional neurological disorders
Role of ALOX5AP in the pathogenesis of cerebral small vessel disease: impact of inflammation and lipid metabolism dysregulation

by myneuronews July 12, 2025

by myneuronews July 12, 2025

Pathophysiological Mechanisms of ALOX5AP ALOX5AP (Arachidonate 5-Lipoxygenase-Activating Protein) plays a pivotal role in the pathophysiology …

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Functional neurological disorders
Lance-Adams Syndrome: Current Understanding and Management

by myneuronews July 11, 2025

by myneuronews July 11, 2025

Overview of Lance-Adams Syndrome Lance-Adams Syndrome (LAS) is a rare neurological condition that emerges following …

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Functional neurological disorders
Lance-Adams Syndrome: Current Understanding and Management

by myneuronews July 11, 2025

by myneuronews July 11, 2025

Understanding Lance-Adams Syndrome Lance-Adams Syndrome is characterized by a specific set of neurological symptoms that …

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Functional neurological disorders
Insights into the Diagnosis, Treatment, and Management of Prion Diseases

by myneuronews July 10, 2025

by myneuronews July 10, 2025

Understanding Prion Diseases Prion diseases, a unique category of neurodegenerative disorders, are caused by misfolded …

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Clinical characteristics and treatment outcomes in patients with Niemann-Pick disease type C (NP-C): a cross-sectional study
Study Overview This research focuses on the clinical characteristics and treatment outcomes of individuals diagnosed…
Large-scale CSF proteome profiling identifies biomarkers for accurate diagnosis of frontotemporal dementia
Study Overview The research presents an extensive analysis aimed at identifying potential biomarkers for frontotemporal…
Functional Neurological Disorder: A Case of Twisted Toes and Dystonia
Understanding Functional Neurological Disorder Functional Neurological Disorder (FND) is characterized by neurological symptoms that cannot…
Predictors of Morbidity and Mortality After Fall-related Traumatic Brain Injury
Study Overview The research conducted on predictors of morbidity and mortality following fall-related traumatic brain…
The effects of color and neutral density filters on dynamic accommodation in individuals with mild traumatic brain injury
Study Overview This study examines how color and neutral density filters affect the dynamic accommodation…

Probing Modulation of Attentional Correlates with Aerobic Exercise in Individuals with a History of Concussion
CONCLUSIONS: The findings demonstrated acute exercise improved accuracy among CH individuals, and performance monitoring is impacted negatively long term following a concussion.
Differential Neuroendocrine Responses and Dysregulation of the Hypothalamic-Pituitary-Adrenal Axis Following Repeated Mild Concussive Impacts and Blast Exposures in a Rat Model
Traumatic brain injury (TBI) remains a significant public health concern, particularly among military personnel and contact sport athletes who are frequently exposed to repeated blast overpressure waves and mild concussive impacts, respectively. While moderate and severe TBIs have been extensively studied, the long-term neuroendocrine consequences of mild, repetitive brain trauma are poorly understood. In this […]
Collision Course: A Decade of Traumatic Brain Injury Trends and the Impact of Urban Safety Initiatives in Eastern Massachusetts
Background/Objectives: Traumatic brain injuries (TBI) account for over a third of all injury-related deaths, predominantly due to motor vehicle collisions (MVC). This study provides a comprehensive analysis of TBI trends in Eastern Massachusetts, focusing on injuries resulting from motorcycle MVCs (mMVC), non-motorcycle MVCs (nmMVC), and pedestrian-vehicle strikes (PVS). Methods: A retrospective analysis was conducted on […]
The interaction between neck pain and known determinates of delayed return to play among NCAA student-athletes: a CARE consortium study
CONCLUSIONS: These results suggest that independent of an individual's sex, sport contact level, and/or race, the presence of neck pain following a suspected concussion should be further evaluated and differentially diagnosed to rule out comorbid pathologies that may be contributing to PPCS following a suspected concussion.
Triamcinolone-loaded nanocarriers: a novel strategy to mitigate cognitive and emotional sequelae induced by traumatic brain injury via modulation of oxidative stress
INTRODUCTION: Traumatic brain injury is the leading cause of death and disability in individuals under 40 years old. It induces various neuropathological outcomes, including cognitive, emotional, and physiological deficits, likely linked to early neuroinflammatory processes. In an animal model, mild traumatic brain injury (mTBI) has been shown to elevate oxidative stress biomarkers, such as advanced […]