Tag:

pathophysiology

Functional neurological disorders
Human PrP E219K: a new and promising substrate for robust RT-QuIC amplification of human prions with potential for strain discrimination

by myneuronews July 10, 2025

by myneuronews July 10, 2025

Overview of Prion Amplification Techniques Prion diseases are a group of progressive neurodegenerative disorders characterized …

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Functional neurological disorders
Current Clinical Applications of Structural MRI in Neurological Disorders

by myneuronews July 10, 2025

by myneuronews July 10, 2025

Current Applications in Neurology Structural MRI has emerged as a crucial tool in the diagnosis …

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Functional neurological disorders
Insights into the Diagnosis, Treatment, and Management of Prion Diseases

by myneuronews July 10, 2025

by myneuronews July 10, 2025

Understanding Prion Diseases Prion diseases, a unique category of neurodegenerative disorders, are caused by misfolded …

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Dementia
Discrepancies between CSF biomarker and PET determinations of elevated brain amyloid and their prognostic significance

by myneuronews July 9, 2025

by myneuronews July 9, 2025

Study Overview The ongoing challenge of accurately diagnosing Alzheimer’s disease and other neurodegenerative conditions has …

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Headaches
Idiopathic hypertrophic pachymeningitis (IHP) causing headache in a young female

by myneuronews July 7, 2025

by myneuronews July 7, 2025

Study Overview This study investigates idiopathic hypertrophic pachymeningitis (IHP), a rare neurological condition characterized by …

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Functional neurological disorders
Retrospective Analysis of Factors Associated with a Prolonged Nucleic Acid Conversion Time in Patients with COVID-19 at Fangcang Shelter Hospital

by myneuronews July 7, 2025

by myneuronews July 7, 2025

Background of Nucleic Acid Conversion in COVID-19 The process of nucleic acid conversion in COVID-19 …

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Dementia
Machine-learning based strategy identifies a robust protein biomarker panel for Alzheimer’s disease in cerebrospinal fluid

by myneuronews July 4, 2025

by myneuronews July 4, 2025

Study Overview The study examines the potential for machine-learning techniques to identify a reliable protein …

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Traumatic brain injury
Comparative analysis of plasma and salivary S100B as predictors of traumatic brain injury severity according to GCS and MAIS/head

by myneuronews July 4, 2025

by myneuronews July 4, 2025

Study Overview The research investigates the efficacy of two biological markers, S100B protein levels in …

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Traumatic brain injury
White matter tract differences in persistent post-traumatic headache, migraine, and healthy controls: a diffusion tensor imaging study

by myneuronews July 4, 2025

by myneuronews July 4, 2025

Study Overview This study investigates the differences in white matter tracts among individuals experiencing persistent …

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Functional neurological disorders
Unveiling cortical criticality changes along the prodromal to the overt continuum of alpha-synucleinopathy

by myneuronews July 3, 2025

by myneuronews July 3, 2025

Cortical Criticality in Alpha-Synucleinopathy The concept of cortical criticality refers to the brain’s ability to …

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Clinical characteristics and treatment outcomes in patients with Niemann-Pick disease type C (NP-C): a cross-sectional study
Study Overview This research focuses on the clinical characteristics and treatment outcomes of individuals diagnosed…
Large-scale CSF proteome profiling identifies biomarkers for accurate diagnosis of frontotemporal dementia
Study Overview The research presents an extensive analysis aimed at identifying potential biomarkers for frontotemporal…
Functional Neurological Disorder: A Case of Twisted Toes and Dystonia
Understanding Functional Neurological Disorder Functional Neurological Disorder (FND) is characterized by neurological symptoms that cannot…
Predictors of Morbidity and Mortality After Fall-related Traumatic Brain Injury
Study Overview The research conducted on predictors of morbidity and mortality following fall-related traumatic brain…
The effects of color and neutral density filters on dynamic accommodation in individuals with mild traumatic brain injury
Study Overview This study examines how color and neutral density filters affect the dynamic accommodation…

Probing Modulation of Attentional Correlates with Aerobic Exercise in Individuals with a History of Concussion
CONCLUSIONS: The findings demonstrated acute exercise improved accuracy among CH individuals, and performance monitoring is impacted negatively long term following a concussion.
Differential Neuroendocrine Responses and Dysregulation of the Hypothalamic-Pituitary-Adrenal Axis Following Repeated Mild Concussive Impacts and Blast Exposures in a Rat Model
Traumatic brain injury (TBI) remains a significant public health concern, particularly among military personnel and contact sport athletes who are frequently exposed to repeated blast overpressure waves and mild concussive impacts, respectively. While moderate and severe TBIs have been extensively studied, the long-term neuroendocrine consequences of mild, repetitive brain trauma are poorly understood. In this […]
Collision Course: A Decade of Traumatic Brain Injury Trends and the Impact of Urban Safety Initiatives in Eastern Massachusetts
Background/Objectives: Traumatic brain injuries (TBI) account for over a third of all injury-related deaths, predominantly due to motor vehicle collisions (MVC). This study provides a comprehensive analysis of TBI trends in Eastern Massachusetts, focusing on injuries resulting from motorcycle MVCs (mMVC), non-motorcycle MVCs (nmMVC), and pedestrian-vehicle strikes (PVS). Methods: A retrospective analysis was conducted on […]
The interaction between neck pain and known determinates of delayed return to play among NCAA student-athletes: a CARE consortium study
CONCLUSIONS: These results suggest that independent of an individual's sex, sport contact level, and/or race, the presence of neck pain following a suspected concussion should be further evaluated and differentially diagnosed to rule out comorbid pathologies that may be contributing to PPCS following a suspected concussion.
Triamcinolone-loaded nanocarriers: a novel strategy to mitigate cognitive and emotional sequelae induced by traumatic brain injury via modulation of oxidative stress
INTRODUCTION: Traumatic brain injury is the leading cause of death and disability in individuals under 40 years old. It induces various neuropathological outcomes, including cognitive, emotional, and physiological deficits, likely linked to early neuroinflammatory processes. In an animal model, mild traumatic brain injury (mTBI) has been shown to elevate oxidative stress biomarkers, such as advanced […]