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patient management

Traumatic brain injury
Comparative analysis of plasma and salivary S100B as predictors of traumatic brain injury severity according to GCS and MAIS/head

by myneuronews July 4, 2025

by myneuronews July 4, 2025

Study Overview This research investigates the roles of plasma and salivary concentrations of S100B protein …

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Traumatic brain injury
The Predictive Value of Heart Rate Variability for the Prognosis of Patients with Mild to Moderate Traumatic Brain Injury

by myneuronews July 4, 2025

by myneuronews July 4, 2025

Predictive Value of Heart Rate Variability Heart rate variability (HRV) refers to the fluctuations in …

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Traumatic brain injury
Comparative analysis of plasma and salivary S100B as predictors of traumatic brain injury severity according to GCS and MAIS/head

by myneuronews July 4, 2025

by myneuronews July 4, 2025

Study Overview The research investigates the efficacy of two biological markers, S100B protein levels in …

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Headaches
The efficacy and safety of intrathecal pemetrexed for leptomeningeal metastasis from non-small cell lung cancer: a single-arm meta-analysis of Chinese patients

by myneuronews July 3, 2025

by myneuronews July 3, 2025

Study Overview This study focuses on evaluating the effectiveness and safety of intrathecal pemetrexed in …

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Traumatic brain injury
Linked alterations in structure and autoimmunity biomarkers in remote mild-to-moderate TBI: A multi-modal brain imaging study

by myneuronews July 3, 2025

by myneuronews July 3, 2025

Study Overview The research focuses on the interrelated effects of structural changes in the brain …

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Functional neurological disorders
Cortical macro- and microstructural changes in isolated rapid eye movement sleep behavior disorder

by myneuronews July 3, 2025

by myneuronews July 3, 2025

Cortical changes in rapid eye movement sleep behavior disorder Recent studies have highlighted significant alterations …

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Functional neurological disorders
A dynamic prediction model for predicting the time at which patients with MCI progress to AD based on time-dependent covariates

by myneuronews July 2, 2025

by myneuronews July 2, 2025

Dynamic Prediction Model Overview The study introduces a dynamic prediction model aimed at forecasting the …

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Functional neurological disorders
Identification of comorbid genes between type 2 diabetes and migraine through peripheral blood single-cell and Mendelian randomization analysis

by myneuronews July 2, 2025

by myneuronews July 2, 2025

Comorbid Gene Identification The identification of comorbid genes linking type 2 diabetes and migraine is …

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Functional neurological disorders
Development of a novel liquid chromatography-tandem mass spectrometry based enzymatic assay of 5,10-methylenetetrahydrofolate reductase

by myneuronews July 2, 2025

by myneuronews July 2, 2025

Enzymatic Assay Development The development of a novel enzymatic assay for 5,10-methylenetetrahydrofolate reductase (MTHFR) taps …

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Traumatic brain injury
Correlation between bispectral index values and the Glasgow Coma Scale in traumatic brain injury patients: a prospective observational study

by myneuronews July 2, 2025

by myneuronews July 2, 2025

Study Overview This study investigates the relationship between the bispectral index (BIS) and the Glasgow …

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Decoding amyloid beta clearance systems at inner blood-retina barrier using three-dimensional ex vivo retinal imaging in Alzheimer’s disease
Amyloid Beta Clearance Mechanisms Amyloid beta (Aβ) is a peptide that plays a crucial role…
Postsurgical psychogenic non-epileptic seizure: a treatment-related functional neurological disorder
Understanding Postsurgical Psychogenic Non-Epileptic Seizures Postsurgical psychogenic non-epileptic seizures (PNES) represent a significant clinical challenge,…
Digital Eye Strain and Associated Risk Factors among Medical Science Students of North India
Digital Eye Strain Prevalence The prevalence of digital eye strain (DES) among medical science students…
Taking Control of Your Functional Cognitive Symptoms: Workbook-A Novel Intervention
Understanding Functional Cognitive Symptoms Functional cognitive symptoms are a complex and often misunderstood aspect of…
Predictors of Skills-Based Psychotherapy Outcomes for Functional Neurological Disorder: A Retrospective Cohort Study
Study Summary The study conducted a thorough investigation into the effectiveness of skills-based psychotherapy for…

Regionally Specific Resting-State Beta Neural Power Predicts Brain Injury and Symptom Recovery in Adolescents with Concussion: A Longitudinal Study
Mild traumatic brain injury (mTBI) is common in adolescents. Magnetoencephalography (MEG) studies (primarily reporting on adult males) have demonstrated abnormal resting-state (RS) brain activity in mTBI. The present study sought to identify RS abnormalities in male and female adolescents with mTBI (no previous Diagnostic and Statistical Manual of Mental Disorders - 5th Edition diagnosis) identified […]
Associations Between Blast Exposures and Intestinal Permeability and Neurotrauma Symptoms During Mortar Fire Military Tactical Training Operations
CONCLUSIONS: The present study in mortarmen corroborates our prior findings showing that exposures to LLB can contribute to IP that is also associated with prior mild traumatic brain injury (mTBI) history, with concomitant decreases in self-reported cognitive functioning. These findings suggest a possible role of blast exposure in gut permeability and the importance of the […]
Midlife plasma proteomic profiles indicate altered amyloid and tau processing in former elite rugby players
CONCLUSIONS: Ex-players showed distinctive plasma biomarker changes, more prominently in ex-forwards, possibly reflecting greater RHI exposure. Plasma KLK6, an endothelial serine protease, was reduced across the ex-player group, with potential diagnostic or prognostic utility in future. Reduced GFAP and SNAP25 in ex-forwards has an uncertain basis, while elevated p-tau-(181) more so than p-tau(217) points towards […]
A Guide to the Interpretation and Reliability of Annual Collegiate ImPACT Baselines by Sex
CONCLUSIONS: This study found sex differences on ImPACT performance, suggesting that sex-specific MDC values are needed to evaluate significant changes in ImPACT scores. Additionally, this study found several ImPACT subtest scores to be unreliable, suggesting only moderate to good scores be used in clinical evaluation.
<em>Taking Control of Your Functional Cognitive Symptoms: Workbook</em>-A Novel Intervention
CONCLUSIONS: This promising new multimodality behavioral health intervention can be considered to be in stage 1 (i.e., intervention generation, refinement, modification, adaptation, and pilot testing). Further pilot testing is being conducted and will need to be followed by traditional efficacy testing (in stage 2).