Tag:

patient outcomes

Functional neurological disorders
Extrapyramidal symptoms as early clinical predictors in first-episode schizophrenia and schizophreniform disorder: findings from the OPTiMiSE trial

by myneuronews July 13, 2025

by myneuronews July 13, 2025

Extrapyramidal Symptoms in First-Episode Schizophrenia Extrapyramidal symptoms (EPS) represent a group of movement disorders that …

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Traumatic brain injury
Integrative Constraint-Based Modeling and Proteomics Uncover Astrocytic Metabolic Adaptations to the Post-TBI Microenvironment

by myneuronews July 12, 2025

by myneuronews July 12, 2025

Study Overview The research explores the metabolic responses of astrocytes, a type of glial cell …

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Functional neurological disorders
Role of ALOX5AP in the pathogenesis of cerebral small vessel disease: impact of inflammation and lipid metabolism dysregulation

by myneuronews July 12, 2025

by myneuronews July 12, 2025

Pathophysiological Mechanisms of ALOX5AP The role of ALOX5AP (Arachidonate 5-Lipoxygenase Activating Protein) in the pathogenesis …

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Functional neurological disorders
Epileptic seizure biophysics: the role of local voltage difference

by myneuronews July 11, 2025

by myneuronews July 11, 2025

Biophysical Mechanisms of Seizures The process of a seizure can be understood through the lens …

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Functional neurological disorders
Mechanical finger sensory stimulation effects on brain function in post-stroke patients: A resting-state fMRI study

by myneuronews July 11, 2025

by myneuronews July 11, 2025

Background and Rationale The recovery process after a stroke can be a challenging journey for …

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Functional neurological disorders
Lance-Adams Syndrome: Current Understanding and Management

by myneuronews July 11, 2025

by myneuronews July 11, 2025

Overview of Lance-Adams Syndrome Lance-Adams Syndrome (LAS) is a rare neurological condition that emerges following …

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Functional neurological disorders
Creutzfeldt-Jakob Disease in South Texas: A Case Series of Three Hispanic Patients

by myneuronews July 11, 2025

by myneuronews July 11, 2025

Case Descriptions In the recent study focusing on Creutzfeldt-Jakob Disease (CJD) among three Hispanic patients …

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Functional neurological disorders
Lance-Adams Syndrome: Current Understanding and Management

by myneuronews July 11, 2025

by myneuronews July 11, 2025

Understanding Lance-Adams Syndrome Lance-Adams Syndrome is characterized by a specific set of neurological symptoms that …

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Functional neurological disorders
Epileptic seizure biophysics: the role of local voltage difference

by myneuronews July 11, 2025

by myneuronews July 11, 2025

Understanding Seizure Mechanisms Seizures are complex neurological events that arise from abnormal electrical activity in …

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Functional neurological disorders
Mechanical finger sensory stimulation effects on brain function in post-stroke patients: A resting-state fMRI study

by myneuronews July 11, 2025

by myneuronews July 11, 2025

Effects of Mechanical Finger Stimulation The study investigated the impact of mechanical finger stimulation on …

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Hidden Threat: A Delayed Diagnosis of an Intracranial Impacted Car Key Leading to Brain Abscess
Case Description A 32-year-old male presented to the emergency department with persistent headaches and episodes…
Associations of diabetes mellitus with primary open angle glaucoma and Alzheimer’s disease: a large cohort study in UK biobank
Study Overview The research investigated the connections between diabetes mellitus, primary open-angle glaucoma (POAG), and…
A Proof-of-Concept Development on Speech Analysis for Concussion Detection
Study Overview This research project aims to explore the potential of speech analysis as a…
Reframing Functional Neurological Disorders in Modern Medicine
Understanding Functional Neurological Disorders Functional Neurological Disorders (FND) represent a category of neurological conditions where…
Youth Ages 4 to 13 Trends of Sports Concussions With Loss of Consciousness From 2014-2023 National Electronic Injury Surveillance System
Study Overview The study investigates the occurrence of sports-related concussions, specifically those leading to loss…

Construct Validity of the Tower of London Test: Generating a Construct Specification Equation Relating Problem Characteristics to Problem Difficulty in a Sample of Veterans with Mild Traumatic Brain Injury
The Tower of London (TOL) is a set of problem-solving tasks that are commonly used to measure cognition. No studies have developed construct specification equations (CSEs) to mathematically quantify how the characteristics of test problems relate to the difficulty of the problem in the TOL. We aimed to investigate the relationship between TOL problem characteristics […]
Vibrational spectroscopy methods reveal biochemical changes associated with the glial scar formation after traumatic brain injury
Traumatic brain injury (TBI) is a serious clinical and social problem. Millions of TBI cases, that require hospitalization and consequently burden social security systems, are reported each year. Analysis of the time course of changes that occur in the brain after primary injury may help indicate therapeutic goals and treatment directions that will minimize severe […]
Functional hearing difficulties in Veterans with blast and blunt head trauma are associated with reduced fractional anisotropy in putative auditory radiations
OBJECTIVES: Veterans of recent military conflicts have experienced a high rate of mild traumatic brain injury (mTBI) due to blast exposure. A debilitating symptom often reported by such patients is an impaired ability to perceive complex sounds (e.g., impaired speech comprehension in noisy environments). In a prior report, we found a continuous measure of historical […]
Clinical outcomes and quality of life after endovascular embolization for vein of Galen aneurysmal malformation (VGAM): a study from a low-and middle-income country
CONCLUSION: The long-term neurological outcomes of VGAM embolization remain variable. While staged embolization was significantly associated with outcomes, other factors may contribute. Larger studies are needed to determine the optimal approach for embolization to improve outcomes.
A Proof-of-Concept Development on Speech Analysis for Concussion Detection
Speech signal analysis to support objective clinical decision-making has gained immense interest, especially in neurological disorders. This research assessed the feasibility of speech analysis on the detection of concussions. Using a speech dataset from 82 concussed and 82 healthy participants, we extracted two speech feature sets focusing on Mel Frequency Cepstral Coefficients (MFCCs) to characterize […]