Signaling pathways driving multiple sclerosis: From mechanisms to natural‑product interventions
Signaling Pathways in Multiple Sclerosis Multiple sclerosis (MS) is a complex autoimmune disease characterized by the immune system’s attack on […]
Distinct remission immune architectures under rituximab and azathioprine in AQP4-IgG-positive neuromyelitis optica spectrum disorder
Study Overview The study focused on examining the distinct immune responses observed in patients with AQP4-IgG-positive neuromyelitis optica spectrum disorder
Machine learning-based identification of concomitant stroke and prognostic analysis in patients with Guillain-Barré syndrome: a retrospective study
Background and Rationale Guillain-Barré syndrome (GBS) is a rare but serious neurological disorder characterized by rapid onset muscle weakness due
Optimizing rare neurological disease trials: Bayesian frameworks and hierarchical models for improved efficiency in clinical trial design
Framework for Bayesian Optimization Bayesian optimization represents a powerful statistical approach that addresses the challenges of designing clinical trials for
Trauma, Emotional Control, Stress Coping Mechanisms, and Illness Acceptance in Individuals With Orofacial Pain, Headache, and Sleep Bruxism
Understanding Orofacial Pain and Associated Conditions Orofacial pain encompasses a range of discomfort localized in the facial and oral regions,
Patent foramen ovale closure, improving fitness after stroke, optimizing hyperacute stroke treatment, and the Global Stroke Action Coalition
Patent Foramen Ovale Closure Techniques Patent foramen ovale (PFO) closure techniques involve a variety of minimally invasive procedures aimed at
Trauma, Emotional Control, Stress Coping Mechanisms, and Illness Acceptance in Individuals With Orofacial Pain, Headache, and Sleep Bruxism
Understanding Orofacial Pain and Related Disorders Orofacial pain encompasses a variety of painful conditions affecting the facial region, particularly the
Late-onset multiple sclerosis is associated with relapse-independent disability accrual: a propensity score-weighted recurrent-event study
Study Overview The investigation centered on understanding the relationship between late-onset multiple sclerosis (MS) and the accumulation of disability independent
CD11c+ CD8 T cells cause IFN-γ-dependent autoimmune neuroinflammation that is restrained by PD-1 signaling
Study Overview This study explores the role of CD11c+ CD8 T cells in the development of autoimmune neuroinflammation, particularly focusing
Viral associations in multiple sclerosis: pathogenetic mechanisms and therapeutic implications
Viral Pathogens and Multiple Sclerosis Multiple sclerosis (MS) is often regarded as an autoimmune disorder where the immune system mistakenly