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patient outcomes

Functional neurological disorders
Clinical and functional outcomes in pediatric patients with Rett syndrome: a 15-year retrospective study

by myneuronews July 3, 2025

by myneuronews July 3, 2025

Clinical Characteristics of Rett Syndrome Rett syndrome is a neurodevelopmental disorder predominantly affecting females, characterized …

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Functional neurological disorders
Changes of functional brain network topology associated with nutritional indicator of patients with recurrent major depressive disorder

by myneuronews July 3, 2025

by myneuronews July 3, 2025

Functional Brain Network Topology and Depression The study of functional brain network topology offers insightful …

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Headaches
The efficacy and safety of intrathecal pemetrexed for leptomeningeal metastasis from non-small cell lung cancer: a single-arm meta-analysis of Chinese patients

by myneuronews July 3, 2025

by myneuronews July 3, 2025

Study Overview This study focuses on evaluating the effectiveness and safety of intrathecal pemetrexed in …

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Traumatic brain injury
Linked alterations in structure and autoimmunity biomarkers in remote mild-to-moderate TBI: A multi-modal brain imaging study

by myneuronews July 3, 2025

by myneuronews July 3, 2025

Study Overview This research focused on the relationship between structural brain alterations and autoimmunity biomarkers …

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Functional neurological disorders
Abnormal static and dynamic regional homogeneity in adolescent major depressive disorder with somatic symptoms: a resting-state fMRI study

by myneuronews July 3, 2025

by myneuronews July 3, 2025

Methodological Overview The study employs a resting-state functional magnetic resonance imaging (fMRI) approach to examine …

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Traumatic brain injury
Proposed Reformulation of Brain Injury Criteria (BrIC) Using Head Rotation-Induced Brain Injury Thresholds Simulated and Derived Directly from A Subhuman Primate Finite Element Model

by myneuronews July 3, 2025

by myneuronews July 3, 2025

Study Overview The investigation presented in this study focuses on redefining the criteria for brain …

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Functional neurological disorders
Quantum magnetization exchange through transient hydrogen bond matrix defines magnetic resonance signal relaxation and anisotropy in central nervous system

by myneuronews July 3, 2025

by myneuronews July 3, 2025

Magnetization Exchange Mechanisms The study explores the intricate processes involved in magnetization exchange mechanisms, which …

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Functional neurological disorders
Unveiling cortical criticality changes along the prodromal to the overt continuum of alpha-synucleinopathy

by myneuronews July 3, 2025

by myneuronews July 3, 2025

Cortical Criticality in Alpha-Synucleinopathy Recent research into alpha-synucleinopathy—disorders associated with the abnormal accumulation of the …

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Functional neurological disorders
Biopsychosocial prognostic indicators in Functional Neurological Disorder: A systematic review

by myneuronews July 3, 2025

by myneuronews July 3, 2025

Prognostic Factors in Functional Neurological Disorder Understanding the prognostic factors associated with Functional Neurological Disorder …

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Traumatic brain injury
Linked alterations in structure and autoimmunity biomarkers in remote mild-to-moderate TBI: A multi-modal brain imaging study

by myneuronews July 3, 2025

by myneuronews July 3, 2025

Study Overview The research focuses on the interrelated effects of structural changes in the brain …

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Cerebral Amyloid Angiopathy-Related Inflammation: Clinical Characteristics and Treatment Experience
Clinical Characteristics Cerebral Amyloid Angiopathy-Related Inflammation (CAA-RI) manifests through a variety of clinical symptoms that…
Collaborative Community Support for People Impacted by Dementia: A Social Return on Investment Analysis
Study Overview This research focuses on understanding the impact of a community-based support program designed…
A cognitive energy crisis: A systematic review & meta-analysis of effective interventions for pediatric cognitive fatigue post-acquired brain injury
Cognitive Fatigue in Pediatric Populations Cognitive fatigue is a significant concern in pediatric populations, particularly…
Investigating the Role of Gut-Derived Neurotoxin TMAO in PTSD Risk Following Traumatic Brain Injury
Study Overview This research investigates the connection between gut-derived neurotoxin trimethylamine N-oxide (TMAO) and the…
ENIGMA’s advanced guide for parcellation error identification (EAGLE-I): An implementation in the context of brain lesions
Study Overview The study focuses on enhancing the accuracy of brain lesion parcellation, a crucial…

Substrate-selective COX-2 inhibition by IMMA attenuates posttraumatic headache via endocannabinoid modulation and neuroinflammatory suppression
CONCLUSION: IMMA effectively attenuates neuroinflammation and pain hypersensitivity in the acute phase of PTH through a distinct mechanism that preserves endocannabinoid tone without suppressing physiological prostaglandins. While these results highlight its promise as a novel therapeutic strategy, further studies are warranted to determine its efficacy during the chronic phase of PTH and across anatomically targeted […]
Intensive exposure therapy for individuals with persistent concussion symptoms following concussion: a replicated single-case experimental design (SCED) study
CONCLUSIONS: The findings of this study further confirmed the efficacy for this intensive exposure therapy for PCS, adding further evidence for exposure therapy in this patient population. Replication in other samples is needed.
Sensory integration processes characterize concussed athletes with balance deficits
Impaired postural control constitutes a major symptom after mild traumatic brain injuries (mTBI/sport-related concussions (SRC)). In order to uphold cognition and behavior during pathological situations, individuals may be characterized by neuronal upregulation. Because postural control necessitates the integration of sensory information within somatosensory (/parietal) cortices, we investigated the hypothesis that athletes with ongoing symptoms after […]
Methods of humane killing of laboratory fish: FELASA Working Group recommendations
As commissioned by the Federation of European Laboratory Animal Science Associations, these working group recommendations define the requirements to achieve the humane killing of fish, compare methods of killing, recommend methods of killing depending on context, and detail protocols leading to good practice. With a review of current practices in a fish laboratory and available […]
Exercise-Induced Symptom Exacerbation and Adverse Events in Moderate-to-Severe Traumatic Brain Injury
CONCLUSIONS: CRF and HLM exertional testing in the early subacute phase of recovery following moderate-to-severe TBI appears to be safe, with low rates of symptom exacerbation and adverse events identified.