Tag:

patient outcomes

Traumatic brain injury
Distinct clinical phenotypes and their neuroanatomic correlates in chronic traumatic brain injury

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Distinct Clinical Phenotypes Chronic traumatic brain injury (TBI) presents a spectrum of clinical phenotypes, each …

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Traumatic brain injury
Association between concomitant traumatic brain injury and unfavorable 1-year outcomes in patients with traumatic spinal cord injury

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Study Overview The investigation centered around the relationship between traumatic brain injury (TBI) and the …

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Traumatic brain injury
Predictive value of peripheral blood inflammatory markers for epilepsy occurrence in traumatic brain injury patients

by myneuronews June 26, 2025

by myneuronews June 26, 2025

Study Overview This study investigates the association between peripheral blood inflammatory markers and the risk …

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Traumatic brain injury
Budget Impact Analysis of the Use of Specific Biomarkers GFAP and UCH-L1 in the Management of Mild Traumatic Brain Injury in Spain

by myneuronews June 26, 2025

by myneuronews June 26, 2025

Background on Mild Traumatic Brain Injury Mild Traumatic Brain Injury (mTBI) is a significant public …

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Traumatic brain injury
Mechanisms Underlying Hyperexcitability: Combining Mossy Fiber Sprouting and Mossy Cell Loss in Neural Network Model of the Dentate Gyrus

by myneuronews June 26, 2025

by myneuronews June 26, 2025

Neurobiological Mechanisms The mechanisms contributing to hyperexcitability in the dentate gyrus—a vital component of the …

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Traumatic brain injury
Bolt gun injury to central forehead, sagittal sinus and frontal lobes: A case report

by myneuronews June 24, 2025

by myneuronews June 24, 2025

Case Presentation A 32-year-old male was admitted to the emergency department following an accidental self-inflicted …

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Traumatic brain injury
Venous thromboembolism prophylaxis in adults with acute traumatic brain injury: a systematic review

by myneuronews June 24, 2025

by myneuronews June 24, 2025

Study Overview This systematic review focuses on the critical issue of venous thromboembolism (VTE) prophylaxis …

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Dementia
Stem Cell-Derived, Fully Differentiated Islets for Type 1 Diabetes

by myneuronews June 22, 2025

by myneuronews June 22, 2025

Background and Rationale The advancement of regenerative medicine has brought to the forefront the potential …

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Traumatic brain injury
Uncovering injury-specific proteomic signatures and neurodegenerative risks in single and repetitive traumatic brain injury

by myneuronews June 22, 2025

by myneuronews June 22, 2025

Injury-Specific Proteomic Signatures In recent research, a growing body of evidence has revealed that distinct …

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Traumatic brain injury
Characterising Postural Orthostatic Tachycardia Syndrome (POTS) triggered by a viral illness compared to concussion or trauma

by myneuronews June 21, 2025

by myneuronews June 21, 2025

Understanding POTS and Its Triggers Postural Orthostatic Tachycardia Syndrome (POTS) is a form of dysautonomia …

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Brain and circulating EV proteome signatures in schizophrenia as prognostic markers for age-related dementia
Prognostic Value of EV Proteome in Schizophrenia The examination of extracellular vesicles (EVs) in schizophrenia…
Are symptoms clustered into latent classes in pediatric functional neurological disorder?
Symptoms Clustering in Pediatric Functional Neurological Disorder Pediatric functional neurological disorder (FND) presents a complex…
An e-Delphi approach to develop a patient-reported outcome measure to assess functional/dissociative seizures severity
Study Overview In recent years, the growing recognition of the impact of functional/dissociative seizures on…
Diagnostic challenges in Burkitt’s lymphoma with skull base and paravertebral involvement, and hearing loss: a case report
Study Overview This case report focuses on Burkitt’s lymphoma, a highly aggressive type of non-Hodgkin…
miR-26b-5p responds to aerobic exercise intervention for concussion recovery in adolescent athletes: a pilot trial
Study Overview The research aimed to investigate the role of miR-26b-5p in the recovery of…

Hyperphosphorylated tau and amyloid-beta proteinopathy in people over age 50: Findings from the Lieber Institute for Brain Development Brain Donation Repository
BackgroundThe Lieber Institute for Brain Development (LIBD) has one of the largest postmortem human brain banks for the study of neuropsychiatric disorders in the world. The postmortem evaluation involves neuropathological assessment for age-related protein accumulations, specifically phosphorylated tau (p-tau) and amyloid-β (Aβ).ObjectivePresent the LIBD semiquantitative assessment methodology for p-tau and Aβ by comparing proteinopathy by […]
Leveraging the Enhanced Sports as a Laboratory Assessment Model to Cross-Validate a Formula Used to Predict Clinical Recovery From Concussion in Collegiate Athletes
CONCLUSIONS: Upon cross-validation, our prognostic formula had limited sensitivity and specificity when predicting clinical recovery after concussion. This formula may be used, with caution, when accompanied by a multidimensional assessment to inform clinical decision making after concussion.
Commentary: Mechanisms of Concussions Among High School Athletes in School-Sponsored Sports: Implications for Safety
No abstract
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This case report describes the clinical response and safety of intranasal esketamine (Spravato®) in a 61-year-old female with treatment-resistant depression (TRD), a history of electroconvulsive therapy (ECT) poor response, and structural brain abnormalities secondary to left frontal lobe tissue loss from traumatic brain injury in 2008. Despite multiple antidepressant trials, atypical antipsychotic augmentation, and 6 […]
Ocular Motor Control and Cognitive Function in Military Veterans With Chronic Mild Traumatic Brain Injury
CONCLUSIONS: Results support the conclusion that OMC and cognitive performance are persistent co-occurring problems in Veterans with chronic mTBI. Notably, these deficits can be detected even after as few as 2 mTBIs that occurred 11 years earlier, indicating that an OMC-cognition axis of sequelae may exist in the chronic stage of mTBI. The results also […]