Tag:

patient outcomes

Traumatic brain injury
The role of two brain injury biomarkers, GFAP and UCH-L1, for the management of mTBI in the Emergency Department: an observational study

by myneuronews June 4, 2025

by myneuronews June 4, 2025

Study Overview This observational study focused on the potential role of two specific brain injury …

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Traumatic brain injury
Pain Management in Mild Traumatic Brain Injury: Central Sensitization as a Multispecialty Challenge

by myneuronews June 4, 2025

by myneuronews June 4, 2025

Understanding Central Sensitization Central sensitization is a crucial phenomenon related to the heightened sensitivity to …

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Traumatic brain injury
Abstracts of the 5th Annual Meeting of the Canadian Concussion Network/Reseau Canadien des Commotions (CCN-RCC)

by myneuronews June 2, 2025

by myneuronews June 2, 2025

Study Overview The 5th Annual Meeting of the Canadian Concussion Network (CCN-RCC) gathered researchers, healthcare …

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Traumatic brain injury
Global trends and psychosocial effects of traumatic brain injury: A bibliometric and machine learning analysis

by myneuronews June 2, 2025

by myneuronews June 2, 2025

Global Trends in Traumatic Brain Injury The incidence of traumatic brain injury (TBI) has emerged …

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Dementia
Study of the Spectrum of Treatable Dementias: Insights from a Large South Asian Cohort (TREAT-Dem Study)

by myneuronews May 30, 2025

by myneuronews May 30, 2025

Overview of Treatable Dementias Dementia encompasses a variety of cognitive impairments caused by different medical …

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Traumatic brain injury
Epidemiology of Traumatic brain injury in Ethiopia: A systematic review and meta-analysis of prevalence, mechanisms, and outcomes

by myneuronews May 30, 2025

by myneuronews May 30, 2025

Epidemiological Context The burden of traumatic brain injury (TBI) in Ethiopia represents a significant public …

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Traumatic brain injury
Identifying and predicting headache trajectories among those with acute post-traumatic headache

by myneuronews May 30, 2025

by myneuronews May 30, 2025

Headache Trajectories Headache trajectories refer to the patterns and progression of headache experiences over time, …

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Traumatic brain injury
Post-Concussion Changes in the Functional Brain Connectome Relative to Pre-Injury Baseline: A Prospective Observational Study

by myneuronews May 30, 2025

by myneuronews May 30, 2025

Study Overview This research investigates alterations in the functional connectivity of the brain before and …

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Traumatic brain injury
Combination Therapy of Estrogen and Progesterone Attenuates Behavioral Impairments and Autophagy via circLrp1b/miR-27a-3p/Dram2 Pathway After Traumatic Brain Injury

by myneuronews May 29, 2025

by myneuronews May 29, 2025

Study Overview The research investigates the effects of combination therapy involving estrogen and progesterone on …

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Traumatic brain injury
Elevation of C-reactive protein and homocysteine levels as reliable biomarkers for assessing injury severity and prognosis in traumatic brain injury

by myneuronews May 29, 2025

by myneuronews May 29, 2025

Biomarkers in Traumatic Brain Injury Biomarkers are measurable indicators in the body that can reflect …

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Brain and circulating EV proteome signatures in schizophrenia as prognostic markers for age-related dementia
Prognostic Value of EV Proteome in Schizophrenia The examination of extracellular vesicles (EVs) in schizophrenia…
Are symptoms clustered into latent classes in pediatric functional neurological disorder?
Symptoms Clustering in Pediatric Functional Neurological Disorder Pediatric functional neurological disorder (FND) presents a complex…
An e-Delphi approach to develop a patient-reported outcome measure to assess functional/dissociative seizures severity
Study Overview In recent years, the growing recognition of the impact of functional/dissociative seizures on…
Diagnostic challenges in Burkitt’s lymphoma with skull base and paravertebral involvement, and hearing loss: a case report
Study Overview This case report focuses on Burkitt’s lymphoma, a highly aggressive type of non-Hodgkin…
miR-26b-5p responds to aerobic exercise intervention for concussion recovery in adolescent athletes: a pilot trial
Study Overview The research aimed to investigate the role of miR-26b-5p in the recovery of…

Hyperphosphorylated tau and amyloid-beta proteinopathy in people over age 50: Findings from the Lieber Institute for Brain Development Brain Donation Repository
BackgroundThe Lieber Institute for Brain Development (LIBD) has one of the largest postmortem human brain banks for the study of neuropsychiatric disorders in the world. The postmortem evaluation involves neuropathological assessment for age-related protein accumulations, specifically phosphorylated tau (p-tau) and amyloid-β (Aβ).ObjectivePresent the LIBD semiquantitative assessment methodology for p-tau and Aβ by comparing proteinopathy by […]
Leveraging the Enhanced Sports as a Laboratory Assessment Model to Cross-Validate a Formula Used to Predict Clinical Recovery From Concussion in Collegiate Athletes
CONCLUSIONS: Upon cross-validation, our prognostic formula had limited sensitivity and specificity when predicting clinical recovery after concussion. This formula may be used, with caution, when accompanied by a multidimensional assessment to inform clinical decision making after concussion.
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This case report describes the clinical response and safety of intranasal esketamine (Spravato®) in a 61-year-old female with treatment-resistant depression (TRD), a history of electroconvulsive therapy (ECT) poor response, and structural brain abnormalities secondary to left frontal lobe tissue loss from traumatic brain injury in 2008. Despite multiple antidepressant trials, atypical antipsychotic augmentation, and 6 […]
Commentary: Mechanisms of Concussions Among High School Athletes in School-Sponsored Sports: Implications for Safety
No abstract
Ocular Motor Control and Cognitive Function in Military Veterans With Chronic Mild Traumatic Brain Injury
CONCLUSIONS: Results support the conclusion that OMC and cognitive performance are persistent co-occurring problems in Veterans with chronic mTBI. Notably, these deficits can be detected even after as few as 2 mTBIs that occurred 11 years earlier, indicating that an OMC-cognition axis of sequelae may exist in the chronic stage of mTBI. The results also […]