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patient outcomes

Functional neurological disorders
Brain-wide microglia replacement using a nonconditioning strategy ameliorates pathology in mouse models of neurological disorders

by myneuronews April 30, 2025

by myneuronews April 30, 2025

Microglia Replacement Strategy The study introduces an innovative approach to addressing neurological disorders through the …

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Functional neurological disorders
Mechanical stress contributes to ligamentum flavum hypertrophy by inducing local inflammation and myofibroblast transition in the innovative surgical rabbit model

by myneuronews April 30, 2025

by myneuronews April 30, 2025

Mechanisms of Ligamentum Flavum Hypertrophy The study delves into the complex changes that occur in …

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Traumatic brain injury
Use of physical exertion to enhance objective testing following mild traumatic brain injury: a systematic review

by myneuronews April 30, 2025

by myneuronews April 30, 2025

Physical Exertion as a Rehabilitation Strategy Physical exertion has gained recognition as a potential rehabilitative …

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Traumatic brain injury
Clinical comparisons between post-traumatic headache and migraine: A cross-sectional study

by myneuronews April 30, 2025

by myneuronews April 30, 2025

Study Overview This study examined the clinical characteristics of post-traumatic headaches (PTH) in comparison to …

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Functional neurological disorders
Neuroimaging Biomarkers of Post-acute Sequelae of Covid (PASC)

by myneuronews April 29, 2025

by myneuronews April 29, 2025

Neuroimaging Techniques and PASC Neuroimaging techniques have emerged as powerful tools in understanding the neurological …

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Functional neurological disorders
Silencer variants are key drivers of gene upregulation in Alzheimer’s disease

by myneuronews April 29, 2025

by myneuronews April 29, 2025

Silencer Variants and Gene Regulation Recent advancements in genetic research have shed light on the …

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Functional neurological disorders
Regulation of chronic neuroinflammation through dietary herbal products

by myneuronews April 29, 2025

by myneuronews April 29, 2025

Role of Dietary Herbal Products in Neuroinflammation Dietary herbal products have garnered significant interest in …

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Traumatic brain injury
Early Pupil Abnormality Frequency Predicts Poor Outcomes and Enhances International Mission for Prognosis and Analysis of Clinical Trials in Traumatic Brain Injury (IMPACT) Model Prognostication in Traumatic Brain Injury

by myneuronews April 29, 2025

by myneuronews April 29, 2025

Early Pupil Abnormality and Its Significance Pupil abnormalities, such as asymmetry or non-reactivity to light, …

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Traumatic brain injury
Retinal manifestations of traumatic brain injury

by myneuronews April 29, 2025

by myneuronews April 29, 2025

Retinal Changes Associated with Traumatic Brain Injury Traumatic brain injury (TBI) can lead to various …

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Headaches
Tuberculous meningitis initially presented with low levels of pleocytosis and protein in the cerebrospinal fluid: a case report

by myneuronews April 28, 2025

by myneuronews April 28, 2025

Clinical Presentation In this case report, a patient initially presented with symptoms that are often …

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Bioequivalence of Two Perampanel Oral Suspension Formulations in Healthy Subjects: A Randomized Crossover Study
Study Overview The investigation focused on comparing the bioequivalence of two formulations of perampanel oral…
In an older-age vascular cohort, carotid stenosis is associated with processing speed and executive function cognitive deficits, which correlate with p-tau217
Study Overview The research focused on understanding the relationship between carotid stenosis and cognitive deficits…
Functional Neurological Disorder, Sleep, and Dreaming: A Large Online Questionnaire-Based Study
Background on Functional Neurological Disorder Functional Neurological Disorder (FND) encompasses a range of neurological symptoms…
Treatments for Functional Neurological Disorder: A Practical Guide for Program Development
Overview of Functional Neurological Disorder Functional Neurological Disorder (FND) presents a unique challenge in both…
On-tools for rehabilitation and cognitive care: Development of a brief intervention for chronic cognitive difficulties after mild traumatic brain injury
Study Overview The investigation focused on addressing the often-overlooked cognitive challenges faced by individuals who…

2Innate immune signaling mediates differential acute and long-term outcomes of repeated vs. single TBI in Drosophila
Traumatic brain injuries (TBIs) are a global source of hospitalization, long-term disability, and death. However, age, sex, and other demographics differ widely among patients and the variable characteristics of TBIs further obscure injury outcomes. Here, we used Drosophila melanogaster to assess the effects of mild, repeated TBI (multi-day, MD) compared to single, severe TBI (single-day, […]
On-tools for rehabilitation and cognitive care: Development of a brief intervention for chronic cognitive difficulties after mild traumatic brain injury
CONCLUSION/IMPLICATIONS: Through a multistep process that incorporated stakeholder input and a review of the empirical literature, we developed an evidence-informed intervention that fills a gap in current care for cognitive PPCSs. Future studies are needed to evaluate the efficacy of this intervention for individuals with chronic cognitive difficulties after mTBI. (PsycInfo Database Record (c) 2025 […]
Comparison of Pre-injury and Clinical Characteristics Between Adolescents With Sport-Related Concussion and Non-Sport-Related Concussion Presenting to a Specialty Concussion Clinic
CONCLUSIONS: The most salient factors associated with non-SRC patients presenting to a specialty concussion clinic were a headache/migraine history, a longer time to clinic, and greater initial visit symptoms. These findings suggest that the factors that lead patients with SRC and Non-SRC to present to a specialty clinic differ, and that studies that are interested […]
Physiatry Reviews for Evidence in Practice (PREP) Second-Order Peer Reviews of Clinically Relevant Articles for the Physiatrist: "Context of Injury and Clinical Trajectories After Mild Traumatic Brain Injury"
No abstract
Biomarkers for prediction of chronic traumatic encephalopathy-like pathology following repeated mild traumatic brain injury in rats are partially sex- and age-dependent
INTRODUCTION: Repeated mild traumatic brain injuries (rmTBIs) pose a high risk of developing chronic traumatic encephalopathy (CTE). Since this neurodegenerative disease is diagnosed only post-mortem, new biomarkers for early detection are needed. Although age at injury and biological sex are important factors in many brain pathologies, little is known about their relevance to rmTBI-induced CTE-like […]