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PCS

Traumatic brain injury
Diffusion Alterations at the Gray Matter/White Matter Boundary in Traumatic Encephalopathy Syndrome

by myneuronews November 11, 2025

by myneuronews November 11, 2025

Diffusion Imaging Techniques Diffusion imaging techniques, particularly diffusion tensor imaging (DTI), have revolutionized the way …

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Traumatic brain injury
Parental and Family Functioning as Predictors of Longitudinal Trajectories of Postconcussive Symptoms Following Pediatric Mild Traumatic Brain Injury: An Advancing Concussion Assessment in Pediatrics Study

by myneuronews November 11, 2025

by myneuronews November 11, 2025

Study Overview The investigation focused on understanding how parental and family dynamics influence the recovery …

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Traumatic brain injury
Kerala Brain Injury Questionnaire: Feasibility, Reliability, and Validation Study

by myneuronews November 11, 2025

by myneuronews November 11, 2025

Study Overview The Kerala Brain Injury Questionnaire (KBIQ) study aimed to assess the feasibility, reliability, …

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Traumatic brain injury
Risk of suicidal behaviors following sport-related and non-sport-related concussion: a systematic review and meta-analysis

by myneuronews November 11, 2025

by myneuronews November 11, 2025

Risk Assessment In exploring the risk of suicidal behaviors following concussions, it is critical to …

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Traumatic brain injury
N-Formylmethionine Is a Biologically Active Diagnostic Marker of Mild Traumatic Brain Injury

by myneuronews November 10, 2025

by myneuronews November 10, 2025

Study Overview This research investigates the role of N-Formylmethionine (fMet) as a potential biomarker for …

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Traumatic brain injury
Three-Month Outcomes of Traumatic Brain Injury in the General Population: A Sunnybrook Traumatic Brain Injury Cohort Study

by myneuronews November 10, 2025

by myneuronews November 10, 2025

Study Overview The investigation examines the aftermath of traumatic brain injuries (TBIs) within a diverse …

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Traumatic brain injury
Chronic Traumatic Encephalopathy Neuropathologic Change in Military Veterans

by myneuronews November 10, 2025

by myneuronews November 10, 2025

Pathophysiology of Chronic Traumatic Encephalopathy Chronic Traumatic Encephalopathy (CTE) is a degenerative brain disease commonly …

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Traumatic brain injury
A novel multimodal pharmacologic approach using guanfacine, N-acetylcysteine, and donepezil in severe TBI: a case series

by myneuronews November 10, 2025

by myneuronews November 10, 2025

Study Overview This study presents a novel approach to treating severe traumatic brain injury (TBI) …

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Traumatic brain injury
Exercise intolerance and time to medical clearance to return to sport following sport-related concussion in adolescents

by myneuronews November 10, 2025

by myneuronews November 10, 2025

Exercise Intolerance in Adolescents Exercise intolerance is a significant concern for adolescents recovering from sport-related …

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Traumatic brain injury
Clinical Recommendations for Female Para and Adaptive Athletes: Perspectives from Current Literature

by myneuronews November 9, 2025

by myneuronews November 9, 2025

Clinical Considerations When working with female para and adaptive athletes, there are several critical factors …

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Extracellular Vesicle-Derived microRNAs as Fluid Biomarkers in Neurodegenerative Diseases: A Systematic Review
Given the absence of curative treatments for neurodegenerative diseases, early detection and therapeutic intervention are critical to slowing disease progression. Extracellular vesicles (EVs) have emerged as promising biomarkers for neurodegeneration, owing to their accessibility in bodily fluids and dynamic molecular cargo, including microRNAs (miRNAs). The last decade has seen accumulating evidence for miRNA dysregulation in […]
P75NTR blockading inhibits Trem2+ M1 phenotype microglia activation and myelin damage following mild traumatic brain injury
The pathological basis underlying mild traumatic brain injury (mTBI)-induced long-term cognitive impairment is not fully understood. It is supposed that mTBI induces residential microglia activation rather than peripheral leukocyte infiltration to promote neuroinflammation, thus triggering myelin damage as well as cognitive impairment. The transformation of microglia towards a pro-inflammatory (M1 type) or anti-inflammatory (M2 type) […]
Biofluid-based predictors of post-concussion symptoms: a narrative review of mild traumatic brain injury biomarkers
Mild traumatic brain injury can disrupt brain function and is associated with high morbidity and healthcare utilization. While many individuals recover from mild traumatic brain injury, a significant proportion experience long-term sequelae, collectively known as post-concussion syndrome. Symptoms of post-concussion syndrome include headache, dizziness, insomnia, cognitive processing difficulties and mental health disturbances. The disease burden […]
Comparison of Six Data Cleaning Methods for Determining Repetitive Head Impact Exposure in Youth Tackle Football
CONCLUSIONS: These findings highlight the impact of data cleaning on HAE quantification in youth tackle football. Although video verification remains best practice, it is resource intensive. Time-windowed, algorithm-classified data may serve as an efficient proxy in similar cohorts, though researchers should recognize its limitations. Findings support the need for standardized data cleaning methods and transparent […]
Effect of Dose of Targeted Rehabilitation Exercises for Vestibular (T-REV) Impairments following mTBI on Dizziness Handicap: A Randomized Clinical Trial
BACKGROUND AND PURPOSE: To evaluate the effect of intensity and frequency of vestibular rehabilitation exercises over time on dizziness handicap and secondary outcomes in adults with vestibular impairments following mild traumatic brain injuries (mTBI).