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PCS

Traumatic brain injury
CCL5/RANTES signaling in inflammation dysregulation after mild traumatic brain injury

by myneuronews January 8, 2026

by myneuronews January 8, 2026

CCL5/RANTES Role in Brain Injury CCL5, also known as RANTES (Regulated upon Activation, Normal T …

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Traumatic brain injury
Repetitive mild traumatic brain injury with the closed-head impact model of engineered rotational acceleration (CHIMERA) promotes tau pathology in tau transgenic mice and its propagation in brains injected with tau fibrils

by myneuronews January 8, 2026

by myneuronews January 8, 2026

Study Overview This study investigates the effects of repetitive mild traumatic brain injury (rmTBI) on …

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Traumatic brain injury
IV dexamethasone as adjuvant therapy to metoclopramide for acute posttraumatic headache in the ED: A randomized controlled trial

by myneuronews January 8, 2026

by myneuronews January 8, 2026

Study Overview This study investigates the effectiveness of intravenous (IV) dexamethasone when used as an …

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Traumatic brain injury
A Longitudinal Study of Error-Related Neural Responses in Adolescents Following Mild Traumatic Brain Injury (mTBI)

by myneuronews January 8, 2026

by myneuronews January 8, 2026

Study Overview The study investigates the neural responses associated with error monitoring in adolescents who …

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Traumatic brain injury
Author’s Reply to: Comment on “Orthostatic Tachycardia in Children With and Without Persisting Postconcussion Symptoms Following Mild Traumatic Brain Injury: A Prospective Controlled Study”

by myneuronews January 8, 2026

by myneuronews January 8, 2026

Study Overview The research focused on comparing the presence and severity of orthostatic tachycardia in …

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Traumatic brain injury
Stability of salivary microRNA measures across an NCAA Division I football season: Implications for microRNA as a biomarker of concussion

by myneuronews January 8, 2026

by myneuronews January 8, 2026

Study Overview The focus of this research is on salivary microRNAs and their stability throughout …

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Traumatic brain injury
Preexisting Mental Health Disorders Are Associated With Acute Clinical Presentation and Longitudinal Recovery Trajectories in Adolescents With Concussion

by myneuronews January 8, 2026

by myneuronews January 8, 2026

Study Overview The focus of this research was to investigate the relationship between preexisting mental …

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Traumatic brain injury
Appropriateness of imaging requests for pediatric traumatic brain injury in the emergency department: a retrospective cross-sectional study

by myneuronews January 8, 2026

by myneuronews January 8, 2026

Study Overview This study was designed to evaluate the appropriateness of imaging requests for pediatric …

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Traumatic brain injury
Anti-Inflammatory Potential of Stearidonic Acid Ethanolamide in a Model of Mild Traumatic Brain Injury in Mice

by myneuronews January 8, 2026

by myneuronews January 8, 2026

Study Overview This study investigates the effects of stearidonic acid ethanolamide (SDA-EA) on inflammation following …

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Traumatic brain injury
Brain creatine concentrations are associated with sex and symptom severity after concussion: a cross-sectional MR-spectroscopy investigation of adolescents with concussion

by myneuronews January 8, 2026

by myneuronews January 8, 2026

Study Overview The investigation focused on the relationship between brain creatine concentrations and both sex …

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Extracellular Vesicle-Derived microRNAs as Fluid Biomarkers in Neurodegenerative Diseases: A Systematic Review
Given the absence of curative treatments for neurodegenerative diseases, early detection and therapeutic intervention are critical to slowing disease progression. Extracellular vesicles (EVs) have emerged as promising biomarkers for neurodegeneration, owing to their accessibility in bodily fluids and dynamic molecular cargo, including microRNAs (miRNAs). The last decade has seen accumulating evidence for miRNA dysregulation in […]
P75NTR blockading inhibits Trem2+ M1 phenotype microglia activation and myelin damage following mild traumatic brain injury
The pathological basis underlying mild traumatic brain injury (mTBI)-induced long-term cognitive impairment is not fully understood. It is supposed that mTBI induces residential microglia activation rather than peripheral leukocyte infiltration to promote neuroinflammation, thus triggering myelin damage as well as cognitive impairment. The transformation of microglia towards a pro-inflammatory (M1 type) or anti-inflammatory (M2 type) […]
Biofluid-based predictors of post-concussion symptoms: a narrative review of mild traumatic brain injury biomarkers
Mild traumatic brain injury can disrupt brain function and is associated with high morbidity and healthcare utilization. While many individuals recover from mild traumatic brain injury, a significant proportion experience long-term sequelae, collectively known as post-concussion syndrome. Symptoms of post-concussion syndrome include headache, dizziness, insomnia, cognitive processing difficulties and mental health disturbances. The disease burden […]
Differences in symptom duration and return to sport following sport-related concussion between French-speaking Canadian and European athletes
CONCLUSION: SRC recovery times differ significantly by geography and sex in French-speaking athletes. European athletes and males report shorter symptom and RTS durations.
Using Cervical Spine Proprioception and Vestibular/Oculomotor Assessments to Identify Return-to-Play Clearance Prognosis After Adolescent Concussion
CONCLUSIONS: Cervical spine proprioception and vestibular/oculomotor symptom provocation evaluated within 3 weeks of injury were not associated with RTP clearance time, potentially reflecting the complexity and multifaceted nature of RTP decisions.