Tag:

personalized medicine

Headaches
Genome-wide associations spanning 194 in-hospital drug dosage change phenotypes highlight diverse genetic backgrounds in concurrent drug therapy

by myneuronews July 18, 2025

by myneuronews July 18, 2025

Study Overview The research aimed to investigate the genetic factors influencing drug dosage adjustments during …

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Traumatic brain injury
Optimizing pediatric “Mild” traumatic brain injury assessments: A multi-domain random forest analysis of diagnosis and outcomes

by myneuronews July 18, 2025

by myneuronews July 18, 2025

Study Overview The research examines the factors influencing the assessment, diagnosis, and outcomes associated with …

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Traumatic brain injury
Multi-ancestry genome-wide meta-analysis of 56,241 individuals identifies known and novel cross-population and ancestry-specific associations as novel risk loci for Alzheimer’s disease

by myneuronews July 17, 2025

by myneuronews July 17, 2025

Study Overview The study aimed to explore the genetic underpinnings of Alzheimer’s disease (AD) through …

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Headaches
Aggressive Craniospinal Recurrence of a PTEN-Mutated Sinonasal Teratocarcinosarcoma: A Case Report

by myneuronews July 15, 2025

by myneuronews July 15, 2025

Case Presentation A 45-year-old male presented with a persistently obstructed nasal passage and occasional epistaxis …

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Traumatic brain injury
Reconsidering cognitive outcome one year after mild traumatic brain injury: Secondary analysis of TRACK-TBI data

by myneuronews July 9, 2025

by myneuronews July 9, 2025

Cognitive Outcomes Post-Injury Mild traumatic brain injury (mTBI) can lead to a range of cognitive …

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Traumatic brain injury
Editorial: Rehabilitation interventions for mild traumatic brain injury

by myneuronews July 9, 2025

by myneuronews July 9, 2025

Rehabilitation Approaches Rehabilitation for mild traumatic brain injury (mTBI) employs a variety of strategies, tailored …

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Dementia
Early outpatient clinical experience with xanomeline and trospium chloride for schizophrenia: a case report

by myneuronews July 7, 2025

by myneuronews July 7, 2025

Study Overview This article presents a detailed examination of the early outpatient clinical experiences involving …

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Traumatic brain injury
Linked alterations in structure and autoimmunity biomarkers in remote mild-to-moderate TBI: A multi-modal brain imaging study

by myneuronews July 3, 2025

by myneuronews July 3, 2025

Study Overview This research focused on the relationship between structural brain alterations and autoimmunity biomarkers …

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Traumatic brain injury
Distinct clinical phenotypes and their neuroanatomic correlates in chronic traumatic brain injury

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Clinical Phenotypes In chronic traumatic brain injury (TBI), individuals often manifest a variety of clinical …

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Dementia
Uncovering Putative Causal Non-Coding RNAs in Acute and Chronic Myeloid Leukemia: A Genome-Wide Mendelian Randomization Study

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Study Overview The investigation aimed to explore the role of non-coding RNAs in the development …

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Establishing the link between post-concussive symptoms and brain network dysfunction: A systematic scoping review of neuroimaging evidence
Mild traumatic brain injury (mTBI) is a prevalent condition with symptoms spanning physical, psychological, cognitive, and sleep domains. Altered functional brain networks have been implicated in mTBI, but the relationship between these network changes and post-concussive symptoms remains poorly understood. This study is a systematic scoping review, adhering to PRISMA-ScR guidelines, assessing current literature on […]
Effect of prior traumatic brain injury on Alzheimer's disease blood biomarkers in Vietnam Veterans
IMPORTANCE: Traumatic brain injury (TBI) is a risk factor for dementia and is known to impact levels of several Alzheimer's disease (AD) blood biomarkers. Plasma pTau217/ Aβ42 ratio has been reported to be 90% accurate for detection of brain amyloid in civilian cohorts.
Repeated Mild Head Injury Establishes a Senescent Cranial Bone Marrow Niche that Impairs Brain Metabolism
Traumatic brain injury (TBI) of any severity is associated with long-term systemic inflammation and increased risk of peripheral comorbidities, yet the mechanisms driving immune dysregulation and accelerated aging after repeated mild head impacts remain poorly defined. Here, we investigated the acute and chronic effects of repeated mild TBI (rmTBI) on distal and proximal bone marrow […]
Commentary on "Examining and Comparing the Clinical Characteristics of Adults with Persisting Post-Concussion Symptoms Presenting for Outpatient Rehabilitation Following a Mild Traumatic Brain Injury or a Minimal Head Injury"
No abstract
Cumulative effects of mild traumatic brain injury in the general population: persistent post-concussion symptoms and post-traumatic stress
CONCLUSIONS: Multiple mTBIs are linked to increased PPCS and PTSD/C-PTSD severity in the general population. Early identification and tailored interventions are essential to reduce long-term psychological and neurological effects.