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personalized medicine

Functional neurological disorders
Electrophysiological characterisation of intranigral-grafted hiPSC-derived dopaminergic neurons in a mouse model of Parkinson’s disease

by myneuronews May 9, 2025

by myneuronews May 9, 2025

Background and Rationale The treatment and study of Parkinson’s disease (PD) continue to evolve, particularly …

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Functional neurological disorders
GWAS by Subtraction to Disentangle RBD Genetic Background from α-Synucleinopathies

by myneuronews May 7, 2025

by myneuronews May 7, 2025

Background and Rationale The study of genetic factors influencing neurological conditions has gained momentum in …

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Functional neurological disorders
Choosing the right treatment for degenerative cervical myelopathy

by myneuronews May 7, 2025

by myneuronews May 7, 2025

Overview of Degenerative Cervical Myelopathy Degenerative cervical myelopathy (DCM) is a progressive condition characterized by …

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Dementia
Temporal transcriptomic changes in the THY-Tau22 mouse model of tauopathy display cell type- and sex-specific differences

by myneuronews May 7, 2025

by myneuronews May 7, 2025

Study Overview The study investigates the temporal changes in gene expression occurring in the brains …

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Functional neurological disorders
GWAS by Subtraction to Disentangle RBD Genetic Background from α-Synucleinopathies

by myneuronews May 7, 2025

by myneuronews May 7, 2025

Overview of RBD and α-Synucleinopathies As research into neurodegenerative disorders continues to evolve, it becomes …

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Functional neurological disorders
Genetic Sketch of Parkinson’s Disease in India

by myneuronews May 7, 2025

by myneuronews May 7, 2025

Genetic Factors in Parkinson’s Disease Parkinson’s Disease (PD) is a multifactorial neurological disorder, with both …

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Traumatic brain injury
Using baseline MRI radiomic features to predict the efficacy of repetitive transcranial magnetic stimulation in Alzheimer’s patients

by myneuronews May 7, 2025

by myneuronews May 7, 2025

Study Overview This study investigates the potential of baseline MRI radiomic features to predict the …

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Functional neurological disorders
Genetic Sketch of Parkinson’s Disease in India

by myneuronews May 7, 2025

by myneuronews May 7, 2025

Genetic Landscape of Parkinson’s Disease in India Parkinson’s Disease (PD) presents a complex interplay of …

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Traumatic brain injury
Using baseline MRI radiomic features to predict the efficacy of repetitive transcranial magnetic stimulation in Alzheimer’s patients

by myneuronews May 7, 2025

by myneuronews May 7, 2025

Study Overview This study investigates the potential of baseline MRI radiomic features to forecast the …

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Functional neurological disorders
Genetic Sketch of Parkinson’s Disease in India

by myneuronews May 7, 2025

by myneuronews May 7, 2025

Genetic Factors Influencing Parkinson’s Disease Parkinson’s Disease (PD) is a progressive neurodegenerative disorder primarily characterized …

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Clinical characteristics and treatment outcomes in patients with Niemann-Pick disease type C (NP-C): a cross-sectional study
Study Overview This research focuses on the clinical characteristics and treatment outcomes of individuals diagnosed…
Large-scale CSF proteome profiling identifies biomarkers for accurate diagnosis of frontotemporal dementia
Study Overview The research presents an extensive analysis aimed at identifying potential biomarkers for frontotemporal…
Functional Neurological Disorder: A Case of Twisted Toes and Dystonia
Understanding Functional Neurological Disorder Functional Neurological Disorder (FND) is characterized by neurological symptoms that cannot…
Predictors of Morbidity and Mortality After Fall-related Traumatic Brain Injury
Study Overview The research conducted on predictors of morbidity and mortality following fall-related traumatic brain…
The effects of color and neutral density filters on dynamic accommodation in individuals with mild traumatic brain injury
Study Overview This study examines how color and neutral density filters affect the dynamic accommodation…

A pilot study evaluating early psychosocial risk and brain health outcomes in Veterans with mild TBI
The goal of this pilot study was to describe the relationship between early psychosocial risk (i.e., adverse childhood experiences, neighborhood disadvantage, multiple relocations) and brain health outcomes among Veterans with mild TBI. Veterans (N = 76) with mild TBI participated at an outpatient VA. This cross-sectional study involved the collection and analysis of retrospective self-report […]
Chronic traumatic encephalopathy
Chronic traumatic encephalopathy (CTE) is a neurodegenerative disease caused by repetitive head impacts from contact sports, physical violence, and other causes. The urgency of the problem is due to the high incidence of pathology, not only in adults, but, most importantly, in the pediatric population. The paper presents a review of the literature in databases […]
Probing Modulation of Attentional Correlates with Aerobic Exercise in Individuals with a History of Concussion
CONCLUSIONS: The findings demonstrated acute exercise improved accuracy among CH individuals, and performance monitoring is impacted negatively long term following a concussion.
Differential Neuroendocrine Responses and Dysregulation of the Hypothalamic-Pituitary-Adrenal Axis Following Repeated Mild Concussive Impacts and Blast Exposures in a Rat Model
Traumatic brain injury (TBI) remains a significant public health concern, particularly among military personnel and contact sport athletes who are frequently exposed to repeated blast overpressure waves and mild concussive impacts, respectively. While moderate and severe TBIs have been extensively studied, the long-term neuroendocrine consequences of mild, repetitive brain trauma are poorly understood. In this […]
Collision Course: A Decade of Traumatic Brain Injury Trends and the Impact of Urban Safety Initiatives in Eastern Massachusetts
Background/Objectives: Traumatic brain injuries (TBI) account for over a third of all injury-related deaths, predominantly due to motor vehicle collisions (MVC). This study provides a comprehensive analysis of TBI trends in Eastern Massachusetts, focusing on injuries resulting from motorcycle MVCs (mMVC), non-motorcycle MVCs (nmMVC), and pedestrian-vehicle strikes (PVS). Methods: A retrospective analysis was conducted on […]