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personalized medicine

Traumatic brain injury
Global trends and psychosocial effects of traumatic brain injury: A bibliometric and machine learning analysis

by myneuronews June 2, 2025

by myneuronews June 2, 2025

Global Trends in Traumatic Brain Injury The landscape of traumatic brain injury (TBI) is shaped …

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Functional neurological disorders
Microglia-drive IRF8 upregulates complement pathway in Parkinson’s disease

by myneuronews June 2, 2025

by myneuronews June 2, 2025

Microglia and Parkinson’s Disease Pathophysiology Microglia, the resident immune cells of the central nervous system, …

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Functional neurological disorders
Clinical cohort study of non inflated subclavian approach,axillary approach,and traditional open surgery for unilateral thyroid cancer

by myneuronews May 30, 2025

by myneuronews May 30, 2025

Study Objectives The primary objective of this clinical cohort study was to evaluate the efficacy …

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Functional neurological disorders
Neuron-Inspired Ferroelectric Bioelectronics for Adaptive Biointerfacing

by myneuronews May 30, 2025

by myneuronews May 30, 2025

Overview of Ferroelectric Bioelectronics Ferroelectric bioelectronics represent a fascinating intersection of materials science and biological …

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Functional neurological disorders
A Convergent Pathway for Stimulation-Induced Dyskinesia Following Deep Brain Stimulation

by myneuronews May 30, 2025

by myneuronews May 30, 2025

Pathophysiology of Stimulation-Induced Dyskinesia The phenomenon of Stimulation-Induced Dyskinesia (SID) emerges as a complex interplay …

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Functional neurological disorders
Diagnostic stability of first onset severe mental illness during postpartum period- findings from a mother-baby unit

by myneuronews May 29, 2025

by myneuronews May 29, 2025

Diagnostic Stability in Postpartum Severe Mental Illness The diagnostic stability of severe mental illness during …

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Traumatic brain injury
Elevation of C-reactive protein and homocysteine levels as reliable biomarkers for assessing injury severity and prognosis in traumatic brain injury

by myneuronews May 29, 2025

by myneuronews May 29, 2025

Biomarkers in Traumatic Brain Injury In the context of traumatic brain injury (TBI), biomarkers serve …

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Traumatic brain injury
Combination Therapy of Estrogen and Progesterone Attenuates Behavioral Impairments and Autophagy via circLrp1b/miR-27a-3p/Dram2 Pathway After Traumatic Brain Injury

by myneuronews May 29, 2025

by myneuronews May 29, 2025

Study Overview The research investigates the effects of combination therapy involving estrogen and progesterone on …

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Functional neurological disorders
Deficits of Alzheimer’s Disease Neuropsychological Architecture Correlate with Specific Exosomal mRNA Expression: Evidence of a Continuum?

by myneuronews May 28, 2025

by myneuronews May 28, 2025

Neuropsychological Deficits in Alzheimer’s Disease Alzheimer’s disease (AD) is often characterized by a progressive decline …

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Dementia
A personalized time-resolved 3D mesh generative model for unveiling normal heart dynamics

by myneuronews May 26, 2025

by myneuronews May 26, 2025

Study Overview The study presents a novel approach to understanding human heart dynamics through the …

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Differential DNA Methylation of the Brain-Derived Neurotrophic Factor Gene is Observed after Pediatric Traumatic Brain Injury Compared with Orthopedic Injury
Pediatric traumatic brain injury (TBI) triggers biological changes that may differ from those observed in non-brain injuries. Brain-derived neurotrophic factor (BDNF) DNA methylation (DNAm) may serve as a novel, dynamic biomarker of the brain's response and help identify TBI-specific epigenetic patterns relevant to later recovery. Therefore, the purpose of this study was to examine whether […]
Patterns, severity, and outcomes of traumatic brain injury in a regional referral hospital in Kenya: a retrospective cohort study
CONCLUSION: The study highlights the high burden of preventable TBI from RTAs and assaults in this setting. The high assault rate, low imaging access, and limited neurosurgical intervention capacity are major concerns. While the findings are limited to admitted patients and short-term outcomes, they underscore the urgent need for targeted road safety initiatives, improved access […]
Efficacy and safety of exosomes from Wharton's Jelly-derived mesenchymal stem cells in traumatic brain injury
CONCLUSION: MSCdE therapy is safe and effective in improving motor function, cognition, and quality of life in TBI patients. Larger, controlled trials are needed to further validate these findings and optimize MSCdE therapy for TBI treatment.
Traumatic Brain Injury Across the Lifespan and in Conflict Zones
Traumatic brain injury is increasingly recognized as a chronic, age-dependent and context-dependent neurological condition rather than being just a singular event. Its incidence, mechanisms, and outcomes may vary across the lifespan, with children, adults, and older adults exhibiting distinct clinical trajectories. These injuries can lead to long-term cognitive, behavioral, and psychosocial challenges that may only […]
Sex Differences in Subacute Blood Biomarker Levels and Associations With Post-Concussion Symptom Severity in Adolescents With Concussion
CONCLUSION: This study highlights sex-specific biomarker differences during adolescent concussion recovery and the importance of understanding how sex differences may influence symptom burden and recovery trajectories. Future research should examine hormonal influences on biomarker profiles and prolonged symptomatology.